Staphylococcus lugdunensis Uses the Agr Regulatory System to Resist Killing by Host Innate Immune Effectors

Inactivation of the Response Regulator AgrA Has a Pleiotropic Effect on Biofilm Formation, Pathogenesis and Stress Response in Staphylococcus lugdunensis

(2022) Marion Aubourg et al.   Microbiology Spectrum

Rational Development of Bacterial Ureases Inhibitors

(2022) Saurabh Loharch et al.   CHEMICAL RECORD

In vivo growth of Staphylococcus lugdunensis is facilitated by the concerted function of heme and non-heme iron acquisition mechanisms

(2022) Ronald S. Flannagan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coagulase-negative staphylococci release a purine analog that inhibits Staphylococcus aureus virulence

(2021) Denny Chin et al.   Nature Communications

Macrophage‐driven nutrient delivery to phagosomal Staphylococcus aureus supports bacterial growth

(2020) Ronald S Flannagan et al.   EMBO REPORTS

An ECF-type transporter scavenges heme to overcome iron-limitation in Staphylococcus lugdunensis

(2020) Angelika Jochim et al.   eLife

Staphylococcus lugdunensis: a Skin Commensal with Invasive Pathogenic Potential

(2020) Simon Heilbronner et al.   CLINICAL MICROBIOLOGY REVIEWS

The surreptitious survival of the emerging pathogen Staphylococcus lugdunensis within macrophages as an immune evasion strategy.

(2018) Ronald S. Flannagan et al.   CELLULAR MICROBIOLOGY

Staphylococcus aureus Uses the GraXRS Regulatory System To Sense and Adapt to the Acidified Phagolysosome in Macrophages

(2018) Ronald S. Flannagan et al.   mBio

Is Staphylococcus lugdunensis Significant in Clinical Samples?

(2017) Xavier Argemi et al.   JOURNAL OF CLINICAL MICROBIOLOGY

The Staphylococcus aureus superantigen SElX is a bifunctional toxin that inhibits neutrophil function

(2017) Stephen W. Tuffs et al.   PLoS Pathogens

Phagocytosis Enhances Lysosomal and Bactericidal Properties by Activating the Transcription Factor TFEB

(2016) Matthew A. Gray et al.   CURRENT BIOLOGY

Shear-Resistant Binding to von Willebrand Factor AllowsStaphylococcus lugdunensisto Adhere to the Cardiac Valves and Initiate Endocarditis

(2016) Laurens Liesenborghs et al.   JOURNAL OF INFECTIOUS DISEASES

Competing for Iron: Duplication and Amplification of the isd Locus in Staphylococcus lugdunensis HKU09-01 Provides a Competitive Advantage to Overcome Nutritional Limitation

(2016) Simon Heilbronner et al.   PLoS Genetics

Intracellular replication ofStaphylococcus aureusin mature phagolysosomes in macrophages precedes host cell death, and bacterial escape and dissemination

(2015) Ronald S. Flannagan et al.   CELLULAR MICROBIOLOGY

Carriage niches and molecular epidemiology of Staphylococcus lugdunensis and methicillin-resistant S. lugdunensis among patients undergoing long-term renal replacement therapy

(2015) Pak-Leung Ho et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

The adhesive properties of the Staphylococcus lugdunensis multifunctional autolysin AtlL and its role in biofilm formation and internalization

(2015) Muzaffar Hussain et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

IsdC from Staphylococcus lugdunensis Induces Biofilm Formation under Low-Iron Growth Conditions

(2014) A. Missineo et al.   INFECTION AND IMMUNITY

Contrasting phagosome pH regulation and maturation in human M1 and M2 macrophages

(2014) Johnathan Canton et al.   MOLECULAR BIOLOGY OF THE CELL

A Secreted Bacterial Protease Tailors the Staphylococcus aureus Virulence Repertoire to Modulate Bone Remodeling during Osteomyelitis

(2013) James E. Cassat et al.   Cell Host & Microbe

Staphylococcus aureus Leukotoxin ED Targets the Chemokine Receptors CXCR1 and CXCR2 to Kill Leukocytes and Promote Infection

(2013) Tamara Reyes-Robles et al.   Cell Host & Microbe

Bacterial Urease and its Role in Long-Lasting Human Diseases

(2013) Iwona Konieczna et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Identification of a Crucial Residue Required for Staphylococcus aureus LukAB Cytotoxicity and Receptor Recognition

(2013) Ashley L. DuMont et al.   INFECTION AND IMMUNITY

Diacylglycerol Kinases Terminate Diacylglycerol Signaling during the Respiratory Burst Leading to Heterogeneous Phagosomal NADPH Oxidase Activation

(2013) Daniel Schlam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Pore-Forming Toxins in Bacterial Infectious Diseases

(2013) F. C. O. Los et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Staphylococcus aureus LukAB cytotoxin kills human neutrophils by targeting the CD11b subunit of the integrin Mac-1

(2013) A. L. DuMont et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell targeting by the Staphylococcus aureus pore-forming toxins: it's not just about lipids

(2013) Ashley L. DuMont et al.   TRENDS IN MICROBIOLOGY

Staphylococcus Lugdunensis, An Aggressive Coagulase-Negative Pathogen not to be Underestimated

(2012) Stefano Ravaioli et al.   INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS

Iron-Regulated Surface Determinant (Isd) Proteins of Staphylococcus lugdunensis

(2012) Marta Zapotoczna et al.   JOURNAL OF BACTERIOLOGY

CCR5 is a receptor for Staphylococcus aureus leukotoxin ED

(2012) Francis Alonzo III et al.   NATURE

Role of the Accessory Gene Regulatoragrin Community-Associated Methicillin-Resistant Staphylococcus aureus Pathogenesis

(2011) Gordon Y. C. Cheung et al.   INFECTION AND IMMUNITY

Staphylococcus lugdunensis IsdG Liberates Iron from Host Heme

(2011) K. P. Haley et al.   JOURNAL OF BACTERIOLOGY

Comparative Analysis of USA300 Virulence Determinants in a Rabbit Model of Skin and Soft Tissue Infection

(2011) Scott D. Kobayashi et al.   JOURNAL OF INFECTIOUS DISEASES

Direct and synergistic hemolysis caused by Staphylococcus phenol-soluble modulins: implications for diagnosis and pathogenesis

(2011) Gordon Y.C. Cheung et al.   MICROBES AND INFECTION

Staphylococcus aureus leucocidin ED contributes to systemic infection by targeting neutrophils and promoting bacterial growth in vivo

(2011) Francis Alonzo III et al.   MOLECULAR MICROBIOLOGY

PtdIns3P and Rac direct the assembly of the NADPH oxidase on a novel, pre-phagosomal compartment during FcR-mediated phagocytosis in primary mouse neutrophils

(2010) K. E. Anderson et al.   BLOOD

Complete Genome Sequence of Staphylococcus lugdunensis Strain HKU09-01

(2010) H. Tse et al.   JOURNAL OF BACTERIOLOGY

A Novel Mechanism of Rapid Nuclear Neutrophil Extracellular Trap Formation in Response to Staphylococcus aureus

(2010) F. H. Pilsczek et al.   JOURNAL OF IMMUNOLOGY

Targeting of Alpha‐Hemolysin by Active or Passive Immunization Decreases Severity of USA300 Skin Infection in a Mouse Model

(2010) Adam D. Kennedy et al.   JOURNAL OF INFECTIOUS DISEASES

Neutrophil Apoptosis: Relevance to the Innate Immune Response and Inflammatory Disease

(2010) Sarah Fox et al.   Journal of Innate Immunity

Importance of the Global Regulators Agr and SaeRS in the Pathogenesis of CA-MRSA USA300 Infection

(2010) Christopher P. Montgomery et al.   PLoS One

From Clinical Microbiology to Infection Pathogenesis: How Daring To Be Different Works for Staphylococcus lugdunensis

(2008) K. L. Frank et al.   CLINICAL MICROBIOLOGY REVIEWS

Microbiological Characteristics, Presumptive Identification, and Antibiotic Susceptibilities of Staphylococcus lugdunensis

(2008) T. Y. Tan et al.   JOURNAL OF CLINICAL MICROBIOLOGY

agr function in clinical Staphylococcus aureus isolates

(2008) K. E. Traber et al.   MICROBIOLOGY-SGM

RNAIII-Independent Target Gene Control by the agr Quorum-Sensing System: Insight into the Evolution of Virulence Regulation in Staphylococcus aureus

(2008) Shu Y. Queck et al.   MOLECULAR CELL