S1PR4 Signaling Attenuates ILT 7 Internalization To Limit IFN-α Production by Human Plasmacytoid Dendritic Cells

MHC Class II–Restricted Antigen Presentation by Plasmacytoid Dendritic Cells Drives Proatherogenic T Cell Immunity

(2014) Andrew P. Sage et al.   CIRCULATION

Increased IFN- -Producing Plasmacytoid Dendritic Cells (pDCs) in Human Th1-Mediated Type 1 Diabetes: pDCs Augment Th1 Responses through IFN-  Production

(2014) C.-Q. Xia et al.   JOURNAL OF IMMUNOLOGY

Effect of Immunoglobin-Like Transcript 7 Cross-Linking on Plasmacytoid Dendritic Cells Differentiation into Antigen-Presenting Cells

(2014) Barbara Tavano et al.   PLoS One

Tumor Promotion by Intratumoral Plasmacytoid Dendritic Cells Is Reversed by TLR7 Ligand Treatment

(2013) I. Le Mercier et al.   CANCER RESEARCH

Necrosis in DU145 prostate cancer spheroids induces COX-2/mPGES-1-derived PGE2to promote tumor growth and to inhibit T cell activation

(2013) Weixiao Sha et al.   INTERNATIONAL JOURNAL OF CANCER

IL-12 and type I interferon prolong the division of activated CD8 T cells by maintaining high-affinity IL-2 signaling in vivo

(2013) Gabriel R. Starbeck-Miller et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antiviral Vaccines License T Cell Responses by Suppressing Granzyme B Levels in Human Plasmacytoid Dendritic Cells

(2013) D. Fabricius et al.   JOURNAL OF IMMUNOLOGY

Ig-like Transcript 7, but Not Bone Marrow Stromal Cell Antigen 2 (Also Known as HM1.24, Tetherin, or CD317), Modulates Plasmacytoid Dendritic Cell Function in Primary Human Blood Leukocytes

(2013) B. Tavano et al.   JOURNAL OF IMMUNOLOGY

Targeting the sphingosine-1-phosphate axis in cancer, inflammation and beyond

(2013) Gregory T. Kunkel et al.   NATURE REVIEWS DRUG DISCOVERY

UNC93B1 mediates differential trafficking of endosomal TLRs

(2013) Bettina L Lee et al.   eLife

DEC-205 is a cell surface receptor for CpG oligonucleotides

(2013) Irina Caminschi et al.   OncoImmunology

Human plasmacytoid dendritic cells are equipped with antigen-presenting and tumoricidal capacities

(2012) J. Tel et al.   BLOOD

Impaired IFN-  Production by Plasmacytoid Dendritic Cells Favors Regulatory T-cell Expansion That May Contribute to Breast Cancer Progression

(2012) V. Sisirak et al.   CANCER RESEARCH

Intracytoplasmic detection of TCL1-but not ILT7-by flow cytometry is useful for blastic plasmacytoid dendritic cell leukemia diagnosis

(2012) Fanny Angelot-Delettre et al.   CYTOMETRY PART A

Apoptotic tumor cells induce IL-27 release from human DCs to activate Treg cells that express CD69 and attenuate cytotoxicity

(2012) Divya Sekar et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mitochondrial Transcription Factor A Serves as a Danger Signal by Augmenting Plasmacytoid Dendritic Cell Responses to DNA

(2012) M. W. Julian et al.   JOURNAL OF IMMUNOLOGY

A Sphingosine-1-Phosphate Receptor 1-Directed Agonist Reduces Central Nervous System Inflammation in a Plasmacytoid Dendritic Cell-Dependent Manner

(2012) G. Galicia-Rosas et al.   JOURNAL OF IMMUNOLOGY

CD8 T Cell Priming in the Presence of IFN-  Renders CTLs with Improved Responsiveness to Homeostatic Cytokines and Recall Antigens: Important Traits for Adoptive T Cell Therapy

(2012) S. Hervas-Stubbs et al.   JOURNAL OF IMMUNOLOGY

The role of TRKA signaling in IL-10 production by apoptotic tumor cell-activated macrophages

(2012) S Ley et al.   ONCOGENE

Pharmacology and therapeutic potential of interferons

(2012) Peter M. George et al.   PHARMACOLOGY & THERAPEUTICS

Regulation of TLR7/9 signaling in plasmacytoid dendritic cells

(2012) Musheng Bao et al.   Protein & Cell

Plasmacytoid dendritic cells infiltrating ovarian cancer are associated with poor prognosis

(2012) Sana Intidhar Labidi-Galy et al.   OncoImmunology

Discovery, design and synthesis of the first reported potent and selective sphingosine-1-phosphate 4 (S1P4) receptor antagonists

(2011) Miguel Guerrero et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonists

(2011) Miguel Guerrero et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

DEC-205 mediates antigen uptake and presentation by both resting and activated human plasmacytoid dendritic cells

(2011) Jurjen Tel et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Sphingosine-1-phospate receptor 4 (S1P4) deficiency profoundly affects dendritic cell function and TH17-cell differentiation in a murine model

(2011) Tobias Schulze et al.   FASEB JOURNAL

Host type I IFN signals are required for antitumor CD8+T cell responses through CD8α+dendritic cells

(2011) Mercedes B. Fuertes et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Type I interferon is selectively required by dendritic cells for immune rejection of tumors

(2011) Mark S. Diamond et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

(2011) Maria T Pallotta et al.   NATURE IMMUNOLOGY

BDCA-2 signaling inhibits TLR-9-agonist-induced plasmacytoid dendritic cell activation and antigen presentation

(2010) Peter S. Jähn et al.   CELLULAR IMMUNOLOGY

Human plasmacytoid dendritic cell accumulation amplifies their type 1 interferon production

(2010) Anne P. Liao et al.   CLINICAL IMMUNOLOGY

Inflammatory cytokines as a third signal for T cell activation

(2010) Julie M Curtsinger et al.   CURRENT OPINION IN IMMUNOLOGY

Unraveling the functions of plasmacytoid dendritic cells during viral infections, autoimmunity, and tolerance

(2010) Melissa Swiecki et al.   IMMUNOLOGICAL REVIEWS

Interferon-alpha regulates the dynamic balance between human activated regulatory and effector T cells: implications for antiviral and autoimmune responses

(2010) Amit Golding et al.   IMMUNOLOGY

Granzyme B produced by human plasmacytoid dendritic cells suppresses T-cell expansion

(2009) B. Jahrsdorfer et al.   BLOOD

Dynamic accumulation of plasmacytoid dendritic cells in lymph nodes is regulated by interferon- 

(2009) Y. Gao et al.   BLOOD

Tumour-derived prostaglandin E2and transforming growth factor-β synergize to inhibit plasmacytoid dendritic cell-derived interferon-α

(2009) Isabelle Bekeredjian-Ding et al.   IMMUNOLOGY

Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction

(2009) Wei Cao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IFN-  Enhances Peptide Vaccine-Induced CD8+ T Cell Numbers, Effector Function, and Antitumor Activity

(2009) A. G. Sikora et al.   JOURNAL OF IMMUNOLOGY

Prostaglandin E2 Inhibits IFN-  Secretion and Th1 Costimulation by Human Plasmacytoid Dendritic Cells via E-Prostanoid 2 and E-Prostanoid 4 Receptor Engagement

(2009) D. Fabricius et al.   JOURNAL OF IMMUNOLOGY

Plasmacytoid Dendritic Cells Capture and Cross-Present Viral Antigens from Influenza-Virus Exposed Cells

(2009) Gabrielle Lui et al.   PLoS One

Regulation of cAMP Responses by the G12/13 Pathway Converges on Adenylyl Cyclase VII

(2008) Lily I. Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY