The Acute-on-Chronic Liver Failure Syndrome, or When the Innate Immune System Goes Astray

Gastrointestinal and hepatic mechanisms limiting entry and dissemination of lipopolysaccharide into the systemic circulation

(2016) Mathilde Guerville et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Systemic inflammation in decompensated cirrhosis: Characterization and role in acute-on-chronic liver failure

(2016) Joan Clària et al.   HEPATOLOGY

Macrophage activation markers predict mortality in patients with liver cirrhosis without or with acute-on-chronic liver failure (ACLF)

(2016) Henning Grønbæk et al.   JOURNAL OF HEPATOLOGY

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

(2016) Xing Liu et al.   NATURE

Lower number and decreased function of natural killer cells in hepatitis B virus related acute-on-chronic liver failure

(2016) Fangfang Liu et al.   Clinics and Research in Hepatology and Gastroenterology

Acute-on-chronic liver failure in cirrhosis

(2016) Vicente Arroyo et al.   Nature Reviews Disease Primers

Patients With Acute-on-Chronic Liver Failure Have Increased Numbers of Regulatory Immune Cells Expressing the Receptor Tyrosine Kinase MERTK

(2015) Christine Bernsmeier et al.   GASTROENTEROLOGY

Clinical Course of acute-on-chronic liver failure syndrome and effects on prognosis

(2015) Thierry Gustot et al.   HEPATOLOGY

Dysbiosis-induced intestinal inflammation activates tumor necrosis factor receptor I and mediates alcoholic liver disease in mice

(2015) Peng Chen et al.   HEPATOLOGY

Mechanisms of decompensation and organ failure in cirrhosis: From peripheral arterial vasodilation to systemic inflammation hypothesis

(2015) Mauro Bernardi et al.   JOURNAL OF HEPATOLOGY

Control of adaptive immunity by the innate immune system

(2015) Akiko Iwasaki et al.   NATURE IMMUNOLOGY

Sepsis-Associated Acute Kidney Injury

(2015) Rashid Alobaidi et al.   SEMINARS IN NEPHROLOGY

Mitochondrial Function and Disturbances in the Septic Kidney

(2015) Samir M. Parikh et al.   SEMINARS IN NEPHROLOGY

RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis

(2014) James A. Rickard et al.   CELL

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

G-CSF: From granulopoietic stimulant to bone marrow stem cell mobilizing agent

(2014) Linda J. Bendall et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Cirrhosis-associated immune dysfunction: Distinctive features and clinical relevance

(2014) Agustín Albillos et al.   JOURNAL OF HEPATOLOGY

Development and validation of a prognostic score to predict mortality in patients with acute-on-chronic liver failure

(2014) Rajiv Jalan et al.   JOURNAL OF HEPATOLOGY

High-mobility group box-1 in sterile inflammation

(2014) A. Tsung et al.   JOURNAL OF INTERNAL MEDICINE

Stress, Inflammation, and Defense of Homeostasis

(2014) Raj Chovatiya et al.   MOLECULAR CELL

Immunosuppression in acutely decompensated cirrhosis is mediated by prostaglandin E2

(2014) Alastair J O'Brien et al.   NATURE MEDICINE

Therapeutic Role of Anakinra, an Interleukin-1 Receptor Antagonist, in the Management of Secondary Hemophagocytic Lymphohistiocytosis/Sepsis/Multiple Organ Dysfunction/Macrophage Activating Syndrome in Critically Ill Children*

(2014) Surender Rajasekaran et al.   Pediatric Critical Care Medicine

Acute-on-Chronic Liver Failure Is a Distinct Syndrome That Develops in Patients With Acute Decompensation of Cirrhosis

(2013) Richard Moreau et al.   GASTROENTEROLOGY

Gene- and exon-expression profiling reveals an extensive LPS-induced response in immune cells in patients with cirrhosis

(2013) Sonia Gandoura et al.   JOURNAL OF HEPATOLOGY

Pathological bacterial translocation in liver cirrhosis

(2013) Reiner Wiest et al.   JOURNAL OF HEPATOLOGY

Natural killer cell recognition and killing of activated hepatic stellate cells

(2012) Joan Clària   GUT

Positive cardiac inotropic effect of albumin infusion in rodents with cirrhosis and ascites: molecular mechanisms

(2012) Alessia Bortoluzzi et al.   HEPATOLOGY

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Disease Tolerance as a Defense Strategy

(2012) R. Medzhitov et al.   SCIENCE

Multiple organ failure in sepsis: prognosis and role of systemic inflammatory response

(2011) Thierry Gustot   Current Opinion in Critical Care

Eosinophils Preserve Parasitic Nematode Larvae by Regulating Local Immunity

(2011) N. G. Gebreselassie et al.   JOURNAL OF IMMUNOLOGY

IL-1  and IL-1  Recruit Different Myeloid Cells and Promote Different Stages of Sterile Inflammation

(2011) P. Rider et al.   JOURNAL OF IMMUNOLOGY

Nomenclature of monocytes and dendritic cells in blood

(2010) L. Ziegler-Heitbrock et al.   BLOOD

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Hepatic Expression of CXC Chemokines Predicts Portal Hypertension and Survival in Patients With Alcoholic Hepatitis

(2009) Marlene Dominguez et al.   GASTROENTEROLOGY

Severe sepsis in cirrhosis

(2009) Thierry Gustot et al.   HEPATOLOGY

Interleukin-1β and the Autoinflammatory Diseases

(2009) Charles A. Dinarello   NEW ENGLAND JOURNAL OF MEDICINE

Alcoholic Hepatitis

(2009) Michael R. Lucey et al.   NEW ENGLAND JOURNAL OF MEDICINE

IL-1, IL-18, and IL-33 families of cytokines

(2008) William P. Arend et al.   IMMUNOLOGICAL REVIEWS

A calculated response: control of inflammation by the innate immune system

(2008) Gregory M. Barton   JOURNAL OF CLINICAL INVESTIGATION

Hepatopulmonary Syndrome — A Liver-Induced Lung Vascular Disorder

(2008) Roberto Rodríguez-Roisin et al.   NEW ENGLAND JOURNAL OF MEDICINE