Obeticholic Acid Protects against Lipopolysaccharide-Induced Fetal Death and Intrauterine Growth Restriction through Its Anti-Inflammatory Activity

Obeticholic acid reduces bacterial translocation and inhibits intestinal inflammation in cirrhotic rats

(2016) María Úbeda et al.   JOURNAL OF HEPATOLOGY

Rosiglitazone pretreatment protects against lipopolysaccharide-induced fetal demise through inhibiting placental inflammation

(2016) Qing-Li Bo et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Obeticholic acid, a synthetic bile acid agonist of the farnesoid X receptor, attenuates experimental autoimmune encephalomyelitis

(2016) Peggy P. Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The FXR Agonist Obeticholic Acid Prevents Gut Barrier Dysfunction and Bacterial Translocation in Cholestatic Rats

(2015) Len Verbeke et al.   AMERICAN JOURNAL OF PATHOLOGY

TLR4 at the Crossroads of Nutrients, Gut Microbiota, and Metabolic Inflammation

(2015) Licio A. Velloso et al.   ENDOCRINE REVIEWS

CXCR3 blockade protects against Listeria monocytogenes infection–induced fetal wastage

(2015) Vandana Chaturvedi et al.   JOURNAL OF CLINICAL INVESTIGATION

Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial

(2015) Brent A Neuschwander-Tetri et al.   LANCET

Lipopolysaccharide-induced murine embryonic resorption involves changes in endocannabinoid profiling and alters progesterone secretion and inflammatory response by a CB1-mediated fashion

(2015) Manuel L. Wolfson et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Agonist of farnesoid X receptor protects against bile acid induced damage and oxidative stress in mouse placenta – A study on maternal cholestasis model

(2015) W.-B. Wu et al.   PLACENTA

Supplementation With Vitamin D3 During Pregnancy Protects Against Lipopolysaccharide-Induced Neural Tube Defects Through Improving Placental Folate Transportation

(2015) Yuan-Hua Chen et al.   TOXICOLOGICAL SCIENCES

Vitamin D3 pretreatment regulates renal inflammatory responses during lipopolysaccharide-induced acute kidney injury

(2015) Shen Xu et al.   Scientific Reports

Vitamin D3 inhibits lipopolysaccharide-induced placental inflammation through reinforcing interaction between vitamin D receptor and nuclear factor kappa B p65 subunit

(2015) Yuan-Hua Chen et al.   Scientific Reports

The integrative roles of chemokines at the maternal–fetal interface in early pregnancy

(2014) Mei-Rong Du et al.   Cellular & Molecular Immunology

Nuclear bile acid signaling through the farnesoid X receptor

(2014) Claire Mazuy et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Transcriptional dynamics of bile salt export pump during pregnancy: Mechanisms and implications in intrahepatic cholestasis of pregnancy

(2014) Xiulong Song et al.   HEPATOLOGY

Inhibition of infection-mediated preterm birth by administration of broad spectrum chemokine inhibitor in mice

(2014) Oksana Shynlova et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Inflammation in rat pregnancy inhibits spiral artery remodeling leading to fetal growth restriction and features of preeclampsia

(2014) Tiziana Cotechini et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Decidual Neutrophil Infiltration Is Not Required for Preterm Birth in a Mouse Model of Infection-Induced Preterm Labor

(2014) S. F. Rinaldi et al.   JOURNAL OF IMMUNOLOGY

TLR4 Activation Enhances the PD-L1–Mediated Tolerogenic Capacity of Colonic CD90+Stromal Cells

(2014) Ellen J. Beswick et al.   JOURNAL OF IMMUNOLOGY

Maternal LPS Exposure during Pregnancy Impairs Testicular Development, Steroidogenesis and Spermatogenesis in Male Offspring

(2014) Hua Wang et al.   PLoS One

Orally Administered Melatonin Prevents Lipopolysaccharide-Induced Neural Tube Defects in Mice

(2014) Lin Fu et al.   PLoS One

Farnesoid X receptor (FXR) gene deficiency impairs urine concentration in mice

(2014) Xiaoyan Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrahepatic cholestasis of pregnancy and associated adverse pregnancy and fetal outcomes: a 12-year population-based cohort study

(2013) E Wikström Shemer et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Interleukin-15 is required for maximal lipopolysaccharide-induced abortion

(2013) Amanda J. Lee et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Folic Acid Protects against Lipopolysaccharide-Induced Preterm Delivery and Intrauterine Growth Restriction through Its Anti-Inflammatory Effect in Mice

(2013) Mei Zhao et al.   PLoS One

Folic acid supplementation during pregnancy protects against lipopolysaccharide-induced neural tube defects in mice

(2013) Mei Zhao et al.   TOXICOLOGY LETTERS

Anti-inflammatory and metabolic actions of FXR: Insights into molecular mechanisms

(2012) Danielle A.A. Hollman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Zinc Supplementation during Pregnancy Protects against Lipopolysaccharide-Induced Fetal Growth Restriction and Demise through Its Anti-inflammatory Effect

(2012) Y.-H. Chen et al.   JOURNAL OF IMMUNOLOGY

Cytokines and the Risk of Preterm Delivery in Twin Pregnancies

(2012) Line Rode et al.   OBSTETRICS AND GYNECOLOGY

Lipopolysaccharide-induced murine embryonic resorption involves nitric oxide-mediated inhibition of the NAD+-dependent 15-hydroxyprostaglandin dehydrogenase

(2012) Julieta Aisemberg et al.   REPRODUCTION

N-acetyl-cysteine (NAC) attenuates LPS-induced maternal and amniotic fluid oxidative stress and inflammatory responses in the preterm gestation

(2011) Nibal Awad et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

(2011) R. M. Gadaleta et al.   GUT

Characterisation of the nuclear receptors FXR, PXR and CAR in normal and cholestatic placenta

(2011) V.L. Geenes et al.   PLACENTA

Umbilical Cord Serum Cytokine Levels and Risks of Small-for-Gestational-Age and Preterm Birth

(2010) G. I. Neta et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Dual effect of nitric oxide on uterine prostaglandin synthesis in a murine model of preterm labour

(2010) M Cella et al.   BRITISH JOURNAL OF PHARMACOLOGY

Alcoholic liver disease and the gut-liver axis

(2010) Gyongyi Szabo   WORLD JOURNAL OF GASTROENTEROLOGY

Farnesoid X receptor agonist WAY-362450 attenuates liver inflammation and fibrosis in murine model of non-alcoholic steatohepatitis

(2009) Songwen Zhang et al.   JOURNAL OF HEPATOLOGY

Age- and gender-dependent impairments of neurobehaviors in mice whose mothers were exposed to lipopolysaccharide during pregnancy

(2009) Hua Wang et al.   TOXICOLOGY LETTERS

Early patterning of the chorion leads to the trilaminar trophoblast cell structure in the placental labyrinth

(2008) D. G. Simmons et al.   DEVELOPMENT

Reactive Oxygen Species Contribute to Lipopolysaccharide-Induced Teratogenesis in Mice

(2008) Lei Zhao et al.   TOXICOLOGICAL SCIENCES