Germinal Center B Cell and T Follicular Helper Cell Responses to Viral Vector and Protein-in-Adjuvant Vaccines

Vaccine Induction of Lymph Node–Resident Simian Immunodeficiency Virus Env-Specific T Follicular Helper Cells in Rhesus Macaques

(2016) Diego A. Vargas-Inchaustegui et al.   JOURNAL OF IMMUNOLOGY

A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA

(2016) Katie Ewer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling

(2015) Kylie M. Quinn et al.   JOURNAL OF CLINICAL INVESTIGATION

Protective Efficacy of Recombinant Modified Vaccinia Virus Ankara Delivering Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein

(2015) Asisa Volz et al.   JOURNAL OF VIROLOGY

Chimpanzee adenovirus– and MVA-vectored respiratory syncytial virus vaccine is safe and immunogenic in adults

(2015) Christopher A. Green et al.   Science Translational Medicine

T Follicular Helper Cell Differentiation, Function, and Roles in Disease

(2014) Shane Crotty   IMMUNITY

Adjuvant-specific regulation of long-term antibody responses by ZBTB20

(2014) Yinan Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Adenovirus Vector-Induced Innate Inflammatory Mediators, MAPK Signaling, As Well As Adaptive Immune Responses Are Dependent upon Both TLR2 and TLR9 In Vivo

(2014) D. M. Appledorn et al.   JOURNAL OF IMMUNOLOGY

Combining Viral Vectored and Protein-in-adjuvant Vaccines Against the Blood-stage Malaria Antigen AMA1: Report on a Phase 1a Clinical Trial

(2014) Susanne H Hodgson et al.   MOLECULAR THERAPY

Rational design of small molecules as vaccine adjuvants

(2014) T. Y.- H. Wu et al.   Science Translational Medicine

Phase II randomized, double-blinded comparison of a single high dose (5×108 TCID50) of modified vaccinia Ankara compared to a standard dose (1×108 TCID50) in healthy vaccinia-naïve individuals

(2014) Sharon E. Frey et al.   VACCINE

Recent advances in antibody-inducing poxviral and adenoviral vectored vaccine delivery platforms for difficult disease targets

(2013) Simone C de Cassan et al.   Expert Review of Vaccines

Comparative Analysis of the Magnitude, Quality, Phenotype, and Protective Capacity of Simian Immunodeficiency Virus Gag-Specific CD8+ T Cells following Human-, Simian-, and Chimpanzee-Derived Recombinant Adenoviral Vector Immunization

(2013) K. M. Quinn et al.   JOURNAL OF IMMUNOLOGY

Utilizing poxviral vectored vaccines for antibody induction—Progress and prospects

(2013) Simon J. Draper et al.   VACCINE

Development and evaluation of AS03, an Adjuvant System containing α-tocopherol and squalene in an oil-in-water emulsion

(2012) Nathalie Garçon et al.   Expert Review of Vaccines

Germinal center selection and the development of memory B and plasma cells

(2012) Mark J. Shlomchik et al.   IMMUNOLOGICAL REVIEWS

Modified Vaccinia Virus Ankara-Based Vaccine Vectors Induce Apoptosis in Dendritic Cells Draining from the Skin via both the Extrinsic and Intrinsic Caspase Pathways, Preventing Efficient Antigen Presentation

(2012) E. Guzman et al.   JOURNAL OF VIROLOGY

ChAd63-MVA–vectored Blood-stage Malaria Vaccines Targeting MSP1 and AMA1: Assessment of Efficacy Against Mosquito Bite Challenge in Humans

(2012) Susanne H Sheehy et al.   MOLECULAR THERAPY

Vaccine Vectors Derived from a Large Collection of Simian Adenoviruses Induce Potent Cellular Immunity Across Multiple Species

(2012) S. Colloca et al.   Science Translational Medicine

The Requirement for Potent Adjuvants To Enhance the Immunogenicity and Protective Efficacy of Protein Vaccines Can Be Overcome by Prior Immunization with a Recombinant Adenovirus

(2011) S. C. de Cassan et al.   JOURNAL OF IMMUNOLOGY

Combining Liver- and Blood-Stage Malaria Viral-Vectored Vaccines: Investigating Mechanisms of CD8+ T Cell Interference

(2011) E. K. Forbes et al.   JOURNAL OF IMMUNOLOGY

Phase Ia Clinical Evaluation of the Plasmodium falciparum Blood-stage Antigen MSP1 in ChAd63 and MVA Vaccine Vectors

(2011) Susanne H Sheehy et al.   MOLECULAR THERAPY

Germinal center B and follicular helper T cells: siblings, cousins or just good friends?

(2011) Stephen L Nutt et al.   NATURE IMMUNOLOGY

Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses

(2011) James J. Moon et al.   NATURE MATERIALS

Transgene Optimization, Immunogenicity and In Vitro Efficacy of Viral Vectored Vaccines Expressing Two Alleles of Plasmodium falciparum AMA1

(2011) Sumi Biswas et al.   PLoS One

Enhancing Blood-Stage Malaria Subunit Vaccine Immunogenicity in Rhesus Macaques by Combining Adenovirus, Poxvirus, and Protein-in-Adjuvant Vaccines

(2010) S. J. Draper et al.   JOURNAL OF IMMUNOLOGY

Multiple Innate Immune Pathways Contribute to the Immunogenicity of Recombinant Adenovirus Vaccine Vectors

(2010) E. G. Rhee et al.   JOURNAL OF VIROLOGY

Tailoring subunit vaccine immunogenicity: Maximizing antibody and T cell responses by using combinations of adenovirus, poxvirus and protein-adjuvant vaccines against Plasmodium falciparum MSP1

(2010) Alexander D. Douglas et al.   VACCINE

The path to a successful vaccine adjuvant – ‘The long and winding road’

(2009) Derek T. O’Hagan et al.   DRUG DISCOVERY TODAY

Kinetics of Recombinant Adenovirus Type 5, Vaccinia Virus, Modified Vaccinia Ankara Virus, and DNA Antigen Expression In Vivo and the Induction of Memory T-Lymphocyte Responses

(2008) R. Geiben-Lynn et al.   Clinical and Vaccine Immunology

Single-Dose Protection against Plasmodium berghei by a Simian Adenovirus Vector Using a Human Cytomegalovirus Promoter Containing Intron A

(2008) S. Sridhar et al.   JOURNAL OF VIROLOGY

Effective induction of high-titer antibodies by viral vector vaccines

(2008) Simon J Draper et al.   NATURE MEDICINE

Development and characterization of a standardized ELISA including a reference serum on each plate to detect antibodies induced by experimental malaria vaccines

(2007) Kazutoyo Miura et al.   VACCINE