Article
Cell Biology
Yu Hao, Xue Li, Ye Zhu, Jianting Ke, Tanqi Lou, Man Li, Cheng Wang
Summary: This study investigated the associations between age-dependent variations in isolated systolic/diastolic hypertension (ISH/IDH) and target organ damage in chronic kidney disease (CKD). It found that ISH was associated with a higher risk of target organ damage regardless of age, while IDH was only correlated with renal injury in younger CKD patients.
Review
Transplantation
Anna Pisano, Francesca Mallamaci, Graziella D'Arrigo, Davide Bolignano, Gregoire Wuerzner, Alberto Ortiz, Michel Burnier, Nada Kanaan, Pantelis Sarafidis, Alexandre Persu, Charles J. Ferro, Charalampos Loutradis, Ioannis N. Boletis, Gerard London, Jean-Michel Halimi, Benedicte Sautenet, Patrick Rossignol, Liffert Vogt, Carmine Zoccali
Summary: This systematic review highlights that ambulatory blood pressure monitoring (ABPM) in kidney transplant recipients (KTRs) is superior to traditional office blood pressure measurements in predicting renal function decline and cardiovascular events. Additionally, an abnormal circadian blood pressure pattern is associated with kidney function loss and cardiovascular abnormalities in KTRs.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2021)
Article
Peripheral Vascular Disease
Jun Zhang, Jun Song, Liping Zhou, Wenying Zhou, Jialing Rao, Yuanqing Li, Jianhao Wu, Hui Peng, Tanqi Lou
Summary: Nocturnal systolic blood pressure (SBP) is independently associated with target organ damage (TOD) in chronic kidney disease (CKD) patients with normotension, while nocturnal diastolic blood pressure (DBP) is not correlated with proteinuria. Targeting a nocturnal SBP to less than 114 mmHg or even less than 104 mmHg may help prevent TOD in patients with CKD.
JOURNAL OF HYPERTENSION
(2021)
Article
Peripheral Vascular Disease
Yi Cheng, Chang-Sheng Sheng, Jian-Feng Huang, Dong-Yan Zhang, Ming-Xuan Li, Yi-Bang Cheng, De-Wei An, Qian-Hui Guo, Ying Wang, Qi-Fang Huang, Ting-Yan Xu, Yan Li, Ji-Guang Wang
Summary: There is seasonal variation in nighttime blood pressure, with the highest levels in summer and the lowest levels in winter. Nighttime blood pressure is positively associated with renal injury in terms of urinary albumin excretion, as well as with other markers of target organ damage. The association between nighttime systolic blood pressure and urinary albumin excretion is stronger in summer compared to winter.
HYPERTENSION RESEARCH
(2023)
Editorial Material
Peripheral Vascular Disease
Cesare Cuspidi, Stefano Carugo, Marijana Tadic
Summary: The study suggests that effective 24-hour blood pressure control and reduction in blood pressure variability may lead to regression of subclinical cardiac damage. However, caution is needed in drawing firm conclusions, and further research is necessary to determine the correlation between reduction of blood pressure variability and regression in cardiac and extracardiac organ damage.
JOURNAL OF CLINICAL HYPERTENSION
(2021)
Article
Peripheral Vascular Disease
Xue Li, Jianting Ke, Xiaoqiu Chen, Mengmeng Yin, Tanqi Lou, Jun Zhang, Hui Peng, Cheng Wang
Summary: Both morning hypertension (MH) and nocturnal hypertension (NH) are associated with severe target organ damage in patients with chronic kidney disease (CKD). The combined presence of MH and NH has stronger effects on target organ damage compared to isolated MH or NH.
JOURNAL OF CLINICAL HYPERTENSION
(2021)
Article
Peripheral Vascular Disease
Janis M. Nolde, Marcio Galindo Kiuchi, Revathy Carnagarin, Shaun Frost, Dennis Kannenkeril, Leslie Marisol Lugo-Gavidia, Justine Chan, Anu Joyson, Vance B. Matthews, Lakshini Y. Herat, Omar Azzam, Markus P. Schlaich
Summary: The study revealed that supine blood pressure measurements may be a valid surrogate for night-time blood pressure when ambulatory monitoring is not accessible, and might be more closely related to hypertensive-mediated organ damage compared to other blood pressure measurement modalities.
JOURNAL OF CLINICAL HYPERTENSION
(2021)
Article
Peripheral Vascular Disease
Julieta S. Del Mauro, Paula D. Prince, Yanina Santander Plantamura, Miguel A. Allo, Luciano Parola, Nahuel Fernandez Machulsky, Marcela A. Moretton, Eliana P. Bin, German E. Gonzalez, Facundo M. Bertera, Andrea Carranza, Gabriela Berg, Carlos A. Taira, Martin Donato, Diego A. Chiappetta, Ariel H. Polizio, Christian Hocht
Summary: By comparing the effects of nebivolol and atenolol on hypertensive rats, it was found that nebivolol was more effective in reducing central systolic blood pressure and blood pressure variability, as well as providing greater protection against target organ damage.
HYPERTENSION RESEARCH
(2021)
Article
Medicine, General & Internal
Tiantian Yu, Shicong Song, Xiaoqiu Chen, Tanqi Lou, Jun Zhang, Hui Peng, Man Li, Cheng Wang
Summary: This study compared the characteristics of ABPM and its relationship with TOD in DKD and PGD patients. The results showed that DKD patients had a higher prevalence of abnormal blood-pressure patterns and were more closely related to target organ damage compared to PGD patients. Further analysis indicated that DKD patients with white-coat hypertension, masked hypertension, and sustained hypertension had closer relationships with TOD.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Peripheral Vascular Disease
George Bakris, Pablo E. Pergola, Belkis Delgado, Diyan Genov, Tamar Doliashvili, Nam Vo, Y. Fred Yang, James McCabe, Vincent Benn, Bertram Pitt
Summary: In patients with resistant or poorly controlled hypertension and advanced chronic kidney disease, the nonsteroidal mineralocorticoid receptor antagonist KBP-5074 effectively lowers blood pressure with some risk of hyperkalemia.
Article
Cardiac & Cardiovascular Systems
Luca Monzo, Joao Pedro Ferreira, Zohra Lamiral, Erwan Bozec, Jean-Marc Boivin, Olivier Huttin, Marilucy Lopez-Sublet, Nicolas Girerd, Faiez Zannad, Patrick Rossignol
Summary: This study aimed to investigate the relationship between isolated diastolic hypertension (IDH) and hypertension-related target organ damage (TOD), finding that IDH was not significantly associated with TOD. Further studies are needed to clarify the clinical role of IDH.
CLINICAL CARDIOLOGY
(2021)
Article
Medicine, General & Internal
Cheol Ho Park, Hyung Woo Kim, Jung Tak Park, Tae Ik Chang, Tae-Hyun Yoo, Sue Kyung Park, Yaeni Kim, Ji Yong Jung, Jong Cheol Jeong, Kook-Hwan Oh, Shin-Wook Kang, Seung Hyeok Han
Summary: The 2021 KDIGO guideline recommends a target systolic blood pressure of <120 mmHg for managing hypertension in chronic kidney disease. It is uncertain whether implementing this target can improve kidney outcomes.
JOURNAL OF INTERNAL MEDICINE
(2023)
Article
Peripheral Vascular Disease
Anping Cai, Lin Liu, Mohammed Siddiqui, Dan Zho, Jiyan Chen, David A. Calhoun, Songtao Tang, Yingling Zhou, Yingqing Feng
Summary: The study found no correlation between serum uric acid levels and 24-hour ambulatory blood pressure monitoring, blood pressure phenotypes, and target organ damage in treated hypertensive patients. This suggests that routine use of 24-hour ABPM in hypertensive patients with increased SUA may not be necessary.
AMERICAN JOURNAL OF HYPERTENSION
(2021)
Article
Peripheral Vascular Disease
Dimone Botha, Yolandi Breet, Aletta E. Schutte
Summary: The study found that in young healthy adults, clinic brachial blood pressure is more strongly correlated with early target organ damage, surpassing central or ambulatory blood pressure. There were no significant differences in the correlations between blood pressure and measures of target organ damage among different ethnic groups.
HYPERTENSION RESEARCH
(2021)
Article
Peripheral Vascular Disease
Young Su Joo, Hyung Woo Kim, Ki Heon Nam, Jee Young Lee, Tae Ik Chang, Jung Tak Park, Tae-Hyun Yoo, Joongyub Lee, Soo Wan Kim, Yun Kyu Oh, Kook-Hwan Oh, Yong-Soo Kim, Curie Ahn, Shin-Wook Kang, Seung Hyeok Han
Summary: In this longitudinal study on CKD, individuals with an increasing SBP trajectory had a significantly higher risk for adverse kidney outcomes compared to those with a stable SBP trajectory, while those with a decreasing SBP trajectory showed a similar risk of adverse kidney outcomes as the stable group.