Epidermal growth factor receptor and AKT1 gene copy numbers by multi-gene fluorescencein situhybridization impact on prognosis in breast cancer

PI3K/AKT/mTOR signaling pathway as a therapeutic target for ovarian cancer

(2014) HaiXia Li et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Multi-gene fluorescence in situ hybridization to detect cell cycle gene copy number aberrations in young breast cancer patients

(2014) Chunyan Li et al.   CELL CYCLE

High EGFR gene copy number predicts poor outcome in triple-negative breast cancer

(2014) Heae Surng Park et al.   MODERN PATHOLOGY

Heterogeneous EGFR Gene Copy Number Increase Is Common in Colorectal Cancer and Defines Response to Anti-EGFR Therapy

(2014) Annika Ålgars et al.   PLoS One

EGFR and TTF-1 Gene Amplification in Surgically Resected Lung Adenocarcinomas: Clinicopathologic Significance and Effect on Response to EGFR-Tyrosine Kinase Inhibitors in Recurred Cases

(2013) Jae Seok Lee et al.   ANNALS OF SURGICAL ONCOLOGY

Epidermal growth factor receptor gene copy number may predict lapatinib sensitivity in HER2-positive metastatic breast cancer

(2013) Alessandra Fabi et al.   EXPERT OPINION ON PHARMACOTHERAPY

The descriptive epidemiology of female breast cancer: An international comparison of screening, incidence, survival and mortality

(2012) Danny R. Youlden et al.   Cancer Epidemiology

Molecular alterations in AKT and its protein activation in human lung carcinomas

(2012) Yoh Dobashi et al.   HUMAN PATHOLOGY

Proximity ligation assays for isoform-specific Akt activation in breast cancer identify activated Akt1 as a driver of progression

(2012) Melanie Spears et al.   JOURNAL OF PATHOLOGY

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Epidermal growth factor receptor in breast carcinoma: association between gene copy number and mutations

(2011) Ning Lv et al.   Diagnostic Pathology

Intratumoral Expression Level of Epidermal Growth Factor Receptor and Cytokeratin 5/6 Is Significantly Associated With Nodal and Distant Metastases in Patients With Basal-like Triple-Negative Breast Carcinoma

(2010) Lisa M. Sutton et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Molecular alterations inAKT1,AKT2andAKT3detected in breast and prostatic cancer by FISH

(2009) Tove Kirkegaard et al.   HISTOPATHOLOGY

Molecular Predictors of Outcome With Gefitinib and Docetaxel in Previously Treated Non–Small-Cell Lung Cancer: Data From the Randomized Phase III INTEREST Trial

(2009) Jean-Yves Douillard et al.   JOURNAL OF CLINICAL ONCOLOGY

PIK3CA Exon 20 Mutation is Independently Associated with a Poor Prognosis in Breast Cancer Patients

(2008) Yuen-Liang Lai et al.   ANNALS OF SURGICAL ONCOLOGY

Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity

(2008) N. Rhodes et al.   CANCER RESEARCH

IncreasedEGFRGene Copy Number Detected by Fluorescent In Situ Hybridization Predicts Outcome in Non–Small-Cell Lung Cancer Patients Treated With Cetuximab and Chemotherapy

(2008) Fred R. Hirsch et al.   JOURNAL OF CLINICAL ONCOLOGY

Molecular analysis of metaplastic breast carcinoma: high EGFR copy number via aneusomy

(2008) J. A. Gilbert et al.   MOLECULAR CANCER THERAPEUTICS

Drug discovery approaches targeting the PI3K/Akt pathway in cancer

(2008) C Garcia-Echeverria et al.   ONCOGENE

PIK3CAcancer mutations display gender and tissue specificity patterns

(2007) Silvia Benvenuti et al.   HUMAN MUTATION