Metabolism of 3-Chlorobiphenyl (PCB 2) in a Human-Relevant Cell Line: Evidence of Dechlorinated Metabolites
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Metabolism of 3-Chlorobiphenyl (PCB 2) in a Human-Relevant Cell Line: Evidence of Dechlorinated Metabolites
Authors
Keywords
-
Journal
ENVIRONMENTAL SCIENCE & TECHNOLOGY
Volume 56, Issue 17, Pages 12460-12472
Publisher
American Chemical Society (ACS)
Online
2022-08-22
DOI
10.1021/acs.est.2c03687
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Characterization of the Metabolic Pathways of 4-Chlorobiphenyl (PCB3) in HepG2 Cells Using the Metabolite Profiles of Its Hydroxylated Metabolites
- (2021) Chun-Yun Zhang et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Passive sampler derived polychlorinated biphenyls (PCBs) in indoor and outdoor air in Bursa, Turkey: Levels and an assessment of human exposure via inhalation
- (2020) Mehmet Ferhat Sari et al. Atmospheric Pollution Research
- Quantification for non-targeted LC/MS screening without standard substances
- (2020) Jaanus Liigand et al. Scientific Reports
- A Critical Review of Polychlorinated Biphenyls Metabolism, Metabolites, and Their Correlation with Oxidative Stress
- (2020) Jing Liu et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Atropselective Partitioning of Polychlorinated Biphenyls in a HepG2 Cell Culture System: Experimental and Modeling Results
- (2020) Chun-Yun Zhang et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Polychlorinated Biphenyls in Food
- (2020) Panithi Saktrakulkla et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- 3,3′-Dichlorobiphenyl Is Metabolized to a Complex Mixture of Oxidative Metabolites, Including Novel Methoxylated Metabolites, by HepG2 Cells
- (2020) Chun-Yun Zhang et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- First polychlorinated biphenyls (PCBs) monitoring in seawater, surface sediments and marine fish communities of the Persian Gulf: Distribution, levels, congener profile and health risk assessment
- (2019) Ali Ranjbar Jafarabadi et al. ENVIRONMENTAL POLLUTION
- In vitro profiling of toxic effects of prominent environmental lower-chlorinated PCB congeners linked with endocrine disruption and tumor promotion
- (2018) Kateřina Pěnčíková et al. ENVIRONMENTAL POLLUTION
- Association of blood polychlorinated biphenyls and cholesterol levels among Canadian Inuit
- (2018) Kavita Singh et al. ENVIRONMENTAL RESEARCH
- Human Liver Microsomes Atropselectively Metabolize 2,2′,3,4′,6-Pentachlorobiphenyl (PCB 91) to a 1,2-Shift Product as the Major Metabolite
- (2018) Eric Uwimana et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Gut Microbiota Modulates Interactions between Polychlorinated Biphenyls and Bile Acid Homeostasis
- (2018) Sunny Lihua Cheng et al. TOXICOLOGICAL SCIENCES
- Identification of a sulfate metabolite of PCB 11 in human serum
- (2017) Fabian A. Grimm et al. ENVIRONMENT INTERNATIONAL
- Microsomal Metabolism of Prochiral Polychlorinated Biphenyls Results in the Enantioselective Formation of Chiral Metabolites
- (2017) Eric Uwimana et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Sources and toxicities of phenolic polychlorinated biphenyls (OH-PCBs)
- (2017) Kiran Dhakal et al. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
- 2,2′,3,5′,6-Pentachlorobiphenyl (PCB 95) Is Atropselectively Metabolized to para-Hydroxylated Metabolites by Human Liver Microsomes
- (2016) Eric Uwimana et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Serum polychlorinated biphenyls and their hydroxylated metabolites are associated with demographic and behavioral factors in children and mothers
- (2016) Wen Xin Koh et al. ENVIRONMENT INTERNATIONAL
- KEGG: new perspectives on genomes, pathways, diseases and drugs
- (2016) Minoru Kanehisa et al. NUCLEIC ACIDS RESEARCH
- Polychlorinated biphenyls
- (2016) Obaid Faroon et al. TOXICOLOGY AND INDUSTRIAL HEALTH
- Metabolism and metabolites of polychlorinated biphenyls
- (2015) Fabian A. Grimm et al. CRITICAL REVIEWS IN TOXICOLOGY
- Human Health Effects of Biphenyl: Key Findings and Scientific Issues
- (2015) Zheng Li et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Tissue Distribution, Metabolism, and Excretion of 3,3′-Dichloro-4′-sulfooxy-biphenyl in the Rat
- (2015) Fabian A. Grimm et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- Disposition of Phenolic and Sulfated Metabolites after Inhalation Exposure to 4-Chlorobiphenyl (PCB3) in Female Rats
- (2014) Kiran Dhakal et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Identifying Small Molecules via High Resolution Mass Spectrometry: Communicating Confidence
- (2014) Emma L. Schymanski et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Phytoremediation and bioremediation of polychlorinated biphenyls (PCBs): State of knowledge and research perspectives
- (2014) Laura Passatore et al. JOURNAL OF HAZARDOUS MATERIALS
- xMSanalyzer: automated pipeline for improved feature detection and downstream analysis of large-scale, non-targeted metabolomics data
- (2013) Karan Uppal et al. BMC BIOINFORMATICS
- Sulfate Conjugates Are Urinary Markers of Inhalation Exposure to 4-Chlorobiphenyl (PCB3)
- (2013) Kiran Dhakal et al. CHEMICAL RESEARCH IN TOXICOLOGY
- The fate of inhaled 14C-labeled PCB11 and its metabolites in vivo
- (2013) Xin Hu et al. ENVIRONMENT INTERNATIONAL
- Sulfated Metabolites of Polychlorinated Biphenyls Are High-Affinity Ligands for the Thyroid Hormone Transport Protein Transthyretin
- (2013) Fabian A. Grimm et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Stereoselective Formation of Mono- and Dihydroxylated Polychlorinated Biphenyls by Rat Cytochrome P450 2B1
- (2013) Zhe Lu et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Elimination of Inhaled 3,3′-Dichlorobiphenyl and the Formation of the 4-Hydroxylated Metabolite
- (2013) Xin Hu et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Predicting Network Activity from High Throughput Metabolomics
- (2013) Shuzhao Li et al. PLoS Computational Biology
- Polychlorinated biphenyls (PCBs) as initiating agents in hepatocellular carcinoma
- (2012) Gabriele Ludewig et al. CANCER LETTERS
- Identification of Sulfated Metabolites of 4-Chlorobiphenyl (PCB3) in the Serum and Urine of Male Rats
- (2012) Kiran Dhakal et al. CHEMICAL RESEARCH IN TOXICOLOGY
- HMDB 3.0—The Human Metabolome Database in 2013
- (2012) David S. Wishart et al. NUCLEIC ACIDS RESEARCH
- New hydroxylated metabolites of 4-monochlorobiphenyl in whole poplar plants
- (2011) Guangshu Zhai et al. Chemistry Central Journal
- Investigation of mechanism(s) of DNA damage induced by 4-monochlorobiphenyl (PCB3) metabolites
- (2010) Wei Xie et al. ENVIRONMENT INTERNATIONAL
- Polyploidy-induction by dihydroxylated monochlorobiphenyls: Structure–activity-relationships
- (2010) Susanne Flor et al. ENVIRONMENT INTERNATIONAL
- In Vitro Assay Shows That PCB Metabolites Completely Saturate Thyroid Hormone Transport Capacity in Blood of Wild Polar Bears (Ursus maritimus)
- (2010) Arno C. Gutleb et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Measuring and modeling of binary mixture effects of pharmaceuticals and nickel on cell viability/cytotoxicity in the human hepatoma derived cell line HepG2
- (2010) S. Rudzok et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- apLCMS—adaptive processing of high-resolution LC/MS data
- (2009) Tianwei Yu et al. BIOINFORMATICS
- Development of a synthetic PCB mixture resembling the average polychlorinated biphenyl profile in Chicago air
- (2009) H.X. Zhao et al. ENVIRONMENT INTERNATIONAL
- Oxidative DNA adducts after Cu2+-mediated activation of dihydroxy PCBs: Role of reactive oxygen species
- (2009) Wendy A. Spencer et al. FREE RADICAL BIOLOGY AND MEDICINE
- Polychlorinated biphenyls emission from a medical waste incinerator in China
- (2009) Tong Chen et al. JOURNAL OF HAZARDOUS MATERIALS
- Contamination and Congener Profiles of Polychlorinated Biphenyls from different agricultural top soils in a county of the Tailake Region, China
- (2009) Hui Wang et al. JOURNAL OF HAZARDOUS MATERIALS
- Nonenzymatic displacement of chlorine and formation of free radicals upon the reaction of glutathione with PCB quinones
- (2009) Y. Song et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Discovery of Non-Aroclor PCB (3,3′-Dichlorobiphenyl) in Chicago Air
- (2008) Dingfei Hu et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Vertical distribution of polychlorinated biphenyl congeners in sediment core from Thane Creek area of Mumbai, India
- (2008) S.K. Sahu et al. JOURNAL OF HAZARDOUS MATERIALS
- Metabolic activation of PCBs to carcinogens in vivo—A review
- (2007) Gabriele Ludewig et al. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started