Cooperatively transcriptional and epigenetic regulation of sonic hedgehog overexpression drives malignant potential of breast cancer

Dual targeting of retinoid X receptor and histone deacetylase with DW22 as a novel antitumor approach

(2015) Lihui Wang et al.   Oncotarget

Identification of anaplastic lymphoma kinase as a potential therapeutic target in Basal Cell Carcinoma

(2015) Hanna Ning et al.   Oncotarget

LINE-1 Hypomethylation, DNA Copy Number Alterations, andCDK6Amplification in Esophageal Squamous Cell Carcinoma

(2014) Yoshifumi Baba et al.   CLINICAL CANCER RESEARCH

Combined DNA methylation and gene expression profiling in gastrointestinal stromal tumors reveals hypomethylation ofSPP1as an independent prognostic factor

(2014) Florian Haller et al.   INTERNATIONAL JOURNAL OF CANCER

Sonic hedgehog signaling may promote invasion and metastasis of oral squamous cell carcinoma by activating MMP-9 and E-cadherin expression

(2014) Hai-Xia Fan et al.   MEDICAL ONCOLOGY

Epigenetic Modifications in Breast Cancer and Their Role in Personalized Medicine

(2013) Olafur A. Stefansson et al.   AMERICAN JOURNAL OF PATHOLOGY

Promoter Hypomethylation of EpCAM-Regulated Bone Morphogenetic Protein Gene Family in Recurrent Endometrial Cancer

(2013) Y.-T. Hsu et al.   CLINICAL CANCER RESEARCH

DNA methylation and nucleosome occupancy regulate the cancer germline antigen geneMAGEA11

(2013) Smitha R James et al.   Epigenetics

Folate deprivation enhances invasiveness of human colon cancer cells mediated by activation of sonic hedgehog signaling through promoter hypomethylation and cross action with transcription nuclear factor-kappa B pathway

(2012) Tz-Ping Wang et al.   CARCINOGENESIS

Activation of the Sonic Hedgehog Pathway and Its Prognostic Impact in Patients with Gastric Cancer

(2012) Zenichiro Saze et al.   DIGESTIVE SURGERY

NMR Structure ofCarcinoscorpius rotundicaudaThioredoxin-related Protein 16 and Its Role in Regulating Transcription Factor NF-κB Activity

(2012) Pankaj Kumar Giri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immunohistochemical evidence of the prognostic value of hedgehog pathway components in primary gallbladder carcinoma

(2012) Jinmao Li et al.   SURGERY TODAY

Hedgehog signaling protein expression and its association with prognostic parameters in prostate cancer: A retrospective study from the view point of new 2010 anatomic stage/prognostic groups

(2011) Tae-Jung Kim et al.   JOURNAL OF SURGICAL ONCOLOGY

Prognostic value of hedgehog signaling pathway in patients with colon cancer

(2011) Meihua Xu et al.   MEDICAL ONCOLOGY

Cancer epigenetics reaches mainstream oncology

(2011) Manuel Rodríguez-Paredes et al.   NATURE MEDICINE

Expression of Hedgehog Pathway Components is Associated with Bladder Cancer Progression and Clinical Outcome

(2011) Hui-chan He et al.   PATHOLOGY & ONCOLOGY RESEARCH

The Hedgehog signalling pathway and its prognostic impact in human gliomas

(2010) Qiaoyu Li et al.   ANZ JOURNAL OF SURGERY

Expression and regulation mechanisms of Sonic Hedgehog in breast cancer

(2010) Wei Cui et al.   CANCER SCIENCE

Aberrant Epigenetic Landscape in Cancer: How Cellular Identity Goes Awry

(2010) María Berdasco et al.   DEVELOPMENTAL CELL

Nuclear factor kappaB-activated monocytes contribute to pancreatic cancer progression through the production of Shh

(2009) Akio Yamasaki et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

NF-κB and cancer: how intimate is this relationship

(2009) Sahdeo Prasad et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Hedgehog Signaling in Development and Cancer

(2008) Jin Jiang et al.   DEVELOPMENTAL CELL

Characterization of sonic hedgehog as a novel NF-κB target gene that promotes NF-κB-mediated apoptosis resistance and tumor growth in vivo

(2008) Hubert Kasperczyk et al.   FASEB JOURNAL