Review
Microbiology
Jessica A. Plante, Brooke M. Mitchell, Kenneth S. Plante, Kari Debbink, Scott C. Weaver, Vineet D. Menachery
Summary: Despite the development of vaccines, COVID-19 caused by SARS-CoV-2 continues to be a global concern due to the emergence of new variants, raising worries about increased spread and potential impacts on immunity.
CELL HOST & MICROBE
(2021)
Review
Clinical Neurology
Rania Daroische, Mathilde S. Hemminghyth, Thomas H. Eilertsen, Monica H. Breitve, Luiza J. Chwiszczuk
Summary: A literature review revealed that patients post COVID-19 may experience global cognitive impairment, memory difficulties, attention and executive function impairment, and verbal fluency issues. It is recommended that clinicians evaluate the need for cognitive assessment in patients with recent COVID-19 infection, and further studies are needed to investigate the condition.
FRONTIERS IN NEUROLOGY
(2021)
Review
Immunology
Yanting Chen, Wenren Yang, Feng Chen, Lili Cui
Summary: COVID-19, caused by SARS-CoV-2, may invade the brains of patients and cause cognitive impairment. The virus can affect cranial nerves and potentially interact with the brain through infected nerve endings and the blood-brain barrier.
JOURNAL OF NEUROINFLAMMATION
(2022)
Review
Multidisciplinary Sciences
Xiaoyu Zhang, Xiao Ge, Fangyuan Shen, Jinjuan Qiao, Yubo Zhang, Heng Li
Summary: This study evaluated the diagnostic value of RPA/RAA integrated with CRISPR technology for COVID-19. The results showed that it can accurately diagnose COVID-19 and can be used for large-scale population screening.
Article
Public, Environmental & Occupational Health
Heather P. McLaughlin, Brian C. Hiatt, Denny Russell, Christina M. Carlson, Jesica R. Jacobs, Ailyn C. Perez-Osorio, Michelle L. Holshue, Sung W. Choi, Romesh K. Gautom
Summary: The paper discusses the collaboration between the Washington State Public Health Laboratory and the Centers for Disease Control and Prevention in responding to the COVID-19 outbreak, highlighting factors contributing to an effective laboratory response and discussing challenges, successful steps, and lessons learned.
AMERICAN JOURNAL OF PUBLIC HEALTH
(2021)
Article
Clinical Neurology
Natalia Gomes Goncalves, Marlon Juliano Romero Aliberti, Laiss Bertola, Thiago Avelino-Silva, Murilo Bacchini Dias, Daniel Apolinario, Geraldo Busatto, Orestes Forlenza, Ricardo Nitrini, Sonia Maria Dozzi Brucki, Andre Russowsky Brunoni, Kallene Summer Moreira Vidal, Wilson Jacob-Filho, Claudia Kimie Suemoto
Summary: Cognitive impairment is common after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. This study explores the associations between post-hospital discharge risk factors and cognitive trajectories in COVID-19 patients. The study found three groups of cognitive trajectories, with older age, female sex, previous dementia diagnosis or memory complaints, frailty before hospitalization, higher platelet count, and delirium as predictors of cognitive decline.
ALZHEIMERS & DEMENTIA
(2023)
Article
Medicine, General & Internal
Tim J. Hartung, Christian Neumann, Thomas Bahmer, Irina Chaplinskaya-Sobol, Matthias Endres, Johanna Geritz, Karl Georg Haeusler, Peter U. Heuschmann, Hanna Hildesheim, Andreas Hinz, Sina Hopff, Anna Horn, Michael Krawczak, Lilian Krist, Jennifer Kudelka, Wolfgang Lieb, Corina Maetzler, Anja Mehnert-Theuerkauf, Felipe A. Montellano, Caroline Morbach, Sein Schmidt, Stefan Schreiber, Flo Steigerwald, Stefan Stoerk, Walter Maetzler, Carsten Finke
Summary: This study aimed to assess the frequency and associated factors of fatigue and cognitive impairment after COVID-19. The results showed that fatigue was more common in COVID-19 patients, especially in females, younger individuals, those with a history of depression, and those with more acute COVID-19 symptoms. Cognitive impairment was also a common sequelae of COVID-19, and it was associated with older age, male gender, lower education level, and a history of neuropsychiatric disease. There was no significant correlation between fatigue and cognitive impairment, and only a small percentage of patients experienced both conditions.
Article
Multidisciplinary Sciences
Xiaojuan Peng, Qi Liu, Zhaolin Chen, Guiyan Wen, Qing Li, Yanfang Chen, Jie Xiong, Xinzhou Meng, Yuanjin Ding, Ying Shi, Shaohui Tang
Summary: Patients with moderate cases of SARS-CoV-2 have a good prognosis with active treatment, but a small proportion of recovered patients may still be virus carriers, necessitating additional rounds of viral detection.
Review
Chemistry, Analytical
Rabia Asghar, Madiha Rasheed, Jalees ul Hassan, Mohsin Rafique, Mashooq Khan, Yulin Deng
Summary: This review discusses the diagnostic platforms for COVID-19, including imaging, molecular-based detection, serological testing, and biosensors. Each platform's principle, advancement, and challenges are discussed in detail, along with an overview of the impact of variants on detection, commercially available kits, and readout signal analysis.
Review
Gastroenterology & Hepatology
Tarik Asselah, David Durantel, Eric Pasmant, George Lau, Raymond F. Schinazi
Summary: COVID-19 started in Wuhan in 2019 and has become a global pandemic. The virus responsible, SARS-CoV-2, shares a high sequence identity with bat- and pangolin-derived coronaviruses. Risk factors for SARS-CoV-2 infection include age, obesity, diabetes, and hypertension.
JOURNAL OF HEPATOLOGY
(2021)
Review
Clinical Neurology
Ezekiel Gonzalez-Fernandez, Juebin Huang
Summary: This narrative review summarizes the cognitive aspects of COVID-19. Studies have consistently identified attention, memory, and executive functions as the most often affected cognitive domains. COVID-19 infection may increase the risks of Alzheimer's disease, suggesting bidirectional relationships.
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS
(2023)
Article
Clinical Neurology
Massimiliano Ruggeri, Monica Ricci, Michela Pagliaro, Carmela Gerace
Summary: Recovered COVID-19 patients commonly experience cognitive disorders, and anosmia may be a good predictor for memory impairments, suggesting a potential route for the virus to infect the brain.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2023)
Article
Clinical Neurology
Joome Suh, Shibani S. Mukerji, Sarah Collens, Robert F. Padera, Geraldine S. Pinkus, Anthony A. Amato, Isaac H. Solomon
Summary: In patients who died after SARS-CoV-2 infection, muscle and nerve tissues showed various pathological changes, predominantly indicating inflammatory/immune-mediated damage possibly related to cytokine release. There was no evidence of direct viral invasion of these tissues.
Article
Multidisciplinary Sciences
Xiao Xiao, Chris Newman, Christina D. Buesching, David W. Macdonald, Zhao-Min Zhou
Summary: The study documents the sale of 47,381 individuals from 38 species in Wuhan's markets, noting the absence of pangolins and bats which supports the theory that they are not the source of the COVID-19 pandemic. China implemented a temporary ban on wildlife trade and a permanent ban on eating and trading terrestrial wild animals to protect human health, address past inconsistencies, and benefit global biodiversity conservation and animal welfare.
SCIENTIFIC REPORTS
(2021)
Review
Microbiology
Jakob J. Malin, Isabelle Suarez, Vanessa Priesner, Gerd Fatkenheuer, Jan Rybniker
Summary: Remdesivir is the first approved treatment for COVID-19, showing therapeutic and prophylactic effects in animal models of various viruses. However, it failed in a clinical trial on ebolavirus disease but showed beneficial effects for patients with COVID-19 in a placebo-controlled trial.
CLINICAL MICROBIOLOGY REVIEWS
(2021)
Article
Clinical Neurology
Emanuela Formaggio, Michele Tonellato, Angelo Antonini, Leonora Castiglia, Laura Gallo, Paolo Manganotti, Stefano Masiero, Alessandra Del Felice
Summary: This study aims to explore the pathophysiological mechanisms of Parkinson disease (PD) by examining changes in EEG rhythms after transcranial magnetic stimulation (TMS). The study found that TMS can temporarily normalize brain oscillations in PD patients, providing a theoretical basis for the development of practical, portable techniques to treat PD symptoms.
JOURNAL OF CLINICAL NEUROPHYSIOLOGY
(2023)
Article
Psychology, Biological
Stefano Vicentin, Giorgia Cona, Giorgio Arcara, Patrizia Bisiacchi
Summary: This study explored the effects of auditory stimuli on prospective memory (PM) and found modality-dependent differences in PM processing. The results showed that auditory and visual stimuli had similar effects on PM processing for low demanding prospective instructions. However, significant differences were found when the prospective load was increased and monitoring requests enhanced, with participants being slower and less accurate with acoustic stimuli.
QUARTERLY JOURNAL OF EXPERIMENTAL PSYCHOLOGY
(2023)
Article
Hospitality, Leisure, Sport & Tourism
Fabio Cannas Aghedu, Mariapia Ghedina, Jais Adam-Troian, Laurence Lux-Sterrit, Pierluigi Graziani, Patrizia S. Bisiacchi
Summary: In recent years, research on high-risk athletes has mainly focused on their personality traits, but there is still a lack of investigation into their affective aspect. This study explores romantic relationship patterns among high-risk athletes and finds that extreme sports athletes tend to display less intense feelings compared to athletes in other sports. However, their sentimental relationships are characterized by positive emotions and stable feelings, avoiding negative emotions.
INTERNATIONAL JOURNAL OF SPORTS SCIENCE & COACHING
(2023)
Review
Psychology, Developmental
Margherita Bertuccelli, Francesca Cantele, Stefano Masiero
Summary: Alterations in body representations, such as body image and body schema, are often overlooked in clinical practice, especially in adolescents affected by idiopathic scoliosis. This scoping review highlights the prevalence of psychological distress and body schema alterations in this clinical population, emphasizing the need for proper evaluation.
ADOLESCENT RESEARCH REVIEW
(2023)
Article
Biophysics
Maria Chiara Maccarone, Giacomo Magro, Claudio Albertin, Giovanni Barbetta, Salvatore Barone, Camilla Castaldelli, Patrizia Manica, Silvia Marcoli, Magda Mediati, Domenico Minuto, Patrizia Poli, Christian Sigurta, Gloria Raffaeta, Stefano Masiero
Summary: This is the first observational study in Italy to evaluate the short-term effects of spa rehabilitation on pain, mood, and quality of life in patients with musculoskeletal disorders. The study found that water-based exercise training alone or in combination with traditional thermal therapy can significantly improve pain, mood, and quality of life in degenerative or post-surgery musculoskeletal disorder patients.
INTERNATIONAL JOURNAL OF BIOMETEOROLOGY
(2023)
Letter
Anesthesiology
Daniele Coraci, Lucrezia Tognolo, Federica Gottardello, Elena Posanti, Stefano Masiero
Article
Surgery
Maria Chiara Maccarone, Erika Venturini, Erica Menegatti, Sergio Gianesini, Stefano Masiero
Summary: This scoping review evaluated the effects of water-based exercise on lymphedema patients by examining clinical studies and randomized controlled trials. Water-based exercise showed potential in improving pain, limb motor function, quality of life, and limb volume in lymphedema patients, but further research is needed to define specific protocols due to the heterogeneity in study populations and physical activity protocols.
JOURNAL OF VASCULAR SURGERY-VENOUS AND LYMPHATIC DISORDERS
(2023)
Article
Clinical Neurology
Marta Campagnolo, Luca Weis, Carmelo Fogliano, Valeria Cianci, Michela Garon, Eleonora Fiorenzato, Miryam Carecchio, Florinda Ferreri, Patrizia Bisiacchi, Angelo Antonini, Roberta Biundo
Summary: The International Parkinson's and Movement Disorder Society (MDS) criteria has expanded the clinical spectrum of progressive supranuclear palsy (PSP) and established phenotypic characterization based on the predominant manifestation at onset. This study aimed to describe the clinical/cognitive and imaging features of a monocentric cohort of PSP patients, highlighting different patterns of functional disability according to the assigned phenotype. The findings support the concept of discrete patterns of Tau pathology within the PSP spectrum and emphasize the importance of tailored approaches in terms of follow-up and treatment.
JOURNAL OF NEURAL TRANSMISSION
(2023)
Article
Neurosciences
Andrea Buccellato, Di Zang, Federico Zilio, Javier Gomez-Pilar, Zhe Wang, Zengxin Qi, Ruizhe Zheng, Zeyu Xu, Xuehai Wu, Patrizia Bisiacchi, Alessandra Del Felice, Ying Mao, Georg Northoff
Summary: Our study examines the role of temporal input processing in consciousness by analyzing different timescales of input processing on resting-state high-density EEG recordings. We found that longer autocorrelation window values and slower alpha peak frequency values were consistently present in unconscious states. Additionally, there was a significant correlation between autocorrelation window and alpha peak frequency in the conscious state, which was disrupted in unconscious states. These findings highlight the importance of brain's capacity for input processing on different timescales for consciousness.
Article
Clinical Neurology
Maria Rubega, Massimiliano Facca, Vittorio Curci, Giovanni Sparacino, Franco Molteni, Eleonora Guanziroli, Stefano Masiero, Emanuela Formaggio, Alessandra Del Felice
Summary: Stroke recovery trajectories vary substantially. The need for tracking and prognostic biomarkers in stroke is utmost for prognostic and rehabilitative goals: electroencephalography (EEG) advanced signal analysis may provide useful tools toward this aim.
Article
Psychology
Giovanni Cantarella, Giovanna Mioni, Patrizia Silvia Bisiacchi
Summary: This study aimed to examine the behavior of healthy young adults performing a time-perception task. Experiment 1 tested the effects of temporary sensory deprivation on visual and auditory senses in young adults, while Experiment 2 compared the temporal performances of young adults with those of children in the auditory modality. The results showed that young adults overestimated time and were more sensitive to it in the auditory modality compared to the visual modality. Restricting visual and auditory input did not affect their time sensitivity. Children were also more accurate at estimating time than young adults after transient visual deprivation.
ATTENTION PERCEPTION & PSYCHOPHYSICS
(2023)
Article
Physics, Multidisciplinary
Andrea Buccellato, Yasir Catal, Patrizia Bisiacchi, Di Zang, Federico Zilio, Zhe Wang, Zengxin Qi, Ruizhe Zheng, Zeyu Xu, Xuehai Wu, Alessandra Del Felice, Ying Mao, Georg Northoff
Summary: In this study, the use of permutation entropy (PE) is proposed to estimate time delays from neural time series, which is a more robust alternative to autocorrelation window (ACW). The validity of this approach is demonstrated on synthetic neural data and hd-EEG human data, suggesting its potential use for characterizing conscious states.
Article
Engineering, Biomedical
Stefano Tortora, Luca Tonin, Sebastian Sieghartsleitner, Rupert Ortner, Christoph Guger, Olive Lennon, Damien Coyle, Emanuele Menegatti, Alessandra Del Felice
Summary: Neurorehabilitation with robotic devices requires a paradigm shift to enhance human-robot interaction. The coupling of robot assisted gait training (RAGT) with a brain-machine interface (BMI) represents an important step in this direction but requires better elucidation of the effect of RAGT on the user's neural modulation.
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2023)
Article
Engineering, Biomedical
Roberto Di Marco, Maria Rubega, Olive Lennon, Asja Vianello, Stefano Masiero, Emanuela Formaggio, Alessandra Del Felice
Summary: Robot-aided gait training (RAGT) is important in physical therapy and it is necessary to understand its impact on brain activity and motor learning. This study measured the neuromuscular effect of a single RAGT session in healthy middle-aged individuals.
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2023)
Article
Behavioral Sciences
Andrea Gajardo-Vidal, Maxime Montembeault, Diego L. Lorca-Puls, Abigail E. Licata, Rian Bogley, Sabrina Erlhoff, Buddhika Ratnasiri, Zoe Ezzes, Giovanni Battistella, Elena Tsoy, Christa Watson Pereira, Jessica Deleon, Boon Lead Tee, Maya L. Henry, Zachary A. Miller, Katherine P. Rankin, Maria Luisa Mandelli, Katherine L. Possin, Maria Luisa Gorno-Tempini
Summary: This study investigates the potential differences in processing speed and neural correlates among the three variants of Primary Progressive Aphasia (PPA). The findings reveal that non-verbal cognitive abilities, such as processing speed, are significantly impacted in nfvPPA and lvPPA patients compared to healthy controls and svPPA patients. Neuroimaging results confirm the importance of fronto-parietal regions associated with processing speed and executive control.
Article
Behavioral Sciences
Holger Wiese, Tsvetomila Popova, Maya Schipper, Deni Zakriev, Mike Burton, Andrew W. Young
Summary: Previous experiments have shown that brief exposure to unfamiliar individuals leads to the formation of new facial representations, which undergo changes and consolidation within the first day after learning.
Article
Behavioral Sciences
Astrid Prochnow, Xianzhen Zhou, Foroogh Ghorbani, Paul Wendiggensen, Veit Roessner, Bernhard Hommel, Christian Beste
Summary: Individuals organize events in their environment by partitioning them into discrete units. This study reveals that the neural activity in the brain plays a critical role in this process, reflecting the key elements of event segmentation.
Article
Behavioral Sciences
Zhenzhen Huo, Zhiyi Chen, Rong Zhang, Junye Xu, Tingyong Feng
Summary: Procrastination has adverse effects on personal growth and social development. Reward sensitivity is positively correlated with procrastination. This study used VBM and RSFC analyses to investigate the neural substrates underlying the association between reward sensitivity and procrastination. The results showed that the functional connectivity of the right parahippocampal gyrus-precuneus mediated the relationship between reward sensitivity and procrastination.
Article
Behavioral Sciences
Stefano Lasaponara, Gabriele Scozia, Silvana Lozito, Mario Pinto, David Conversi, Marco Costanzi, Tim Vriens, Massimo Silvetti, Fabrizio Doricchi
Summary: Cholinergic (Ach), Noradrenergic (NE), and Dopaminergic (DA) pathways are crucial in regulating spatial attention and determining inter-individual differences in temperamental traits. This study found that temperamental traits predict individual differences in the ability to orient spatial attention based on the probabilistic association between cues and targets. These findings highlight the importance of considering temperamental and personality traits in social and professional environments where attention control is essential.
Article
Behavioral Sciences
Darren J. Yeo, Courtney Pollack, Benjamin N. Conrad, Gavin R. Price
Summary: The processing of numerals as visual objects is supported by an Inferior Temporal Numeral Area (ITNA) in the bilateral inferior temporal gyri (ITG). Extant findings suggest some degree of hemispheric asymmetry in how the bilateral ITNAs process numerals. The study found that digit sensitivity did not differ between ITNAs, and digit sensitivity in both left and right ITNAs was associated with calculation skills. The study also revealed a right lateralization in engagement in alphanumeric categorization, and that the right ITNA showed greater discriminability between digits and letters.
Review
Behavioral Sciences
Beste Gulsuna, Abuzer Gungor, Alp O. Borcer, Ugur Ture
Summary: The fiber dissection technique has been used to study the internal structures of the brain, with less focus on white matter. The sagittal stratum, a white matter structure, has not received enough attention and has been a subject of controversy. Recent studies suggest potential functions of the sagittal stratum, emphasizing the importance of understanding this structure accurately.
Article
Behavioral Sciences
Nora Geiser, Brigitte Charlotte Kaufmann, Samuel Elia Johannes Knobel, Dario Cazzoli, Tobias Nef, Thomas Nyffeler
Summary: This study compared the effects of auditory and visual motion stimulation on spatial neglect and found that both interventions were equally effective in improving neglect. Multimodal motion stimulation also improved neglect, but did not show greater improvement than unimodal auditory or visual motion stimulation alone.
Article
Behavioral Sciences
Anna E. Hughes, Anna Nowakowska, Alasdair D. F. Clarke
Summary: This study examines the relationship between search slopes and search efficiency in visual search tasks, introduces the Target Contrast Signal (TCS) Theory, and extends it to a Bayesian multi-level framework. The findings demonstrate that TCS can predict data well, but distinguishing between contrast combination models proves to be difficult.
