4.1 Article

Diagnosis and Management of Acute Pancreatitis in Pregnancy

Journal

CLINICAL OBSTETRICS AND GYNECOLOGY
Volume 66, Issue 1, Pages 237-249

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/GRF.0000000000000737

Keywords

acute pancreatitis; pregnancy; biliary disease

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Acute pancreatitis is a rare condition during pregnancy, but due to its associated morbidity and mortality, it is crucial to diagnose and manage it promptly. Mild cases can be improved with limited interventions, while severe cases require a multidisciplinary approach in a critical care setting. The main principles of management include identifying the cause, fluid resuscitation, electrolyte repletion, early nutritional support, and pain management. Antibiotics are not recommended for prophylaxis and should only be used if there is a suspected infectious process. Surgical management may be necessary in certain cases. The management of pregnant patients has some unique considerations which will be outlined below.
Acute pancreatitis is rare in pregnancy; however, the associated morbidity and mortality make prompt diagnosis and appropriate management essential.(1,2) Although most cases are mild and improve with limited interventions, severe cases require a multidisciplinary approach in a critical care setting. The main principles of management include identification of an etiology to guide therapy, fluid resuscitation, electrolyte repletion, early nutritional support, and pain management. Antibiotics are not indicated for prophylaxis and should be reserved for cases with a suspected infectious process. Surgical management is indicated in select cases. Management in pregnant patients has few differences which are outlined below.

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