Journal
CLIMACTERIC
Volume 25, Issue 6, Pages 570-578Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/13697137.2022.2122792
Keywords
Menopause; perimenopause; cognition; memory; menopausal hormone therapy; dementia
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Midlife women often experience changes in cognitive function during menopause, and healthcare practitioners play a crucial role in guiding and normalizing these changes. This paper provides an overview of clinical data and a framework for clinical counseling for menopausal women.
Midlife women commonly experience changes in their cognitive function as they transition through menopause and express concern about whether these changes represent the initial stages of a more serious cognitive disorder. Health-care practitioners play an important role in counseling women on cognitive changes at midlife and normalizing women's experience. The aim of this commissioned International Menopause Society White Paper on cognition is to provide practitioners with an overview of data informing the clinical care of menopausal women and a framework for clinical counseling and decision-making. Among the topics presented are the specific cognitive changes occurring in menopause, the duration of such changes and their severity. The role of estrogen and menopause symptoms is reviewed. We present talking points for clinical counseling on the effects of hormone therapy on cognition and dementia risk in women, including discussion of absolute risk. Lastly, a brief review of modifiable risk factors for age-related cognitive decline and dementia is presented, with guidance for counseling patients on optimizing their brain health at midlife and beyond.
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