Article
Chemistry, Physical
Muhammad Ishfaq, Muhammad Aadil, Syeda Rabia Ejaz, Warda Hassan, Nadia Masaya Panduro-Tenazoa, Mohamed E. El Sayed, Mohammad N. Murshed, Zeinhom M. El-Bahy
Summary: In this study, a copper and bismuth co-doped CeO2 nanostructure was synthesized using subcritical hydrothermal method for water remediation application. The co-doping of copper and bismuth synergistically improved the conductivity and light-harvesting capabilities of the co-doped CeO2, as confirmed through current-voltage and optical studies. The microstructural, compositional, and morphological information of the photocatalyst were analyzed using powder XRD and spectroscopic techniques. The as-prepared co-doped CeO2-based photocatalyst demonstrated efficient mineralization of the anionic dye methyl orange under solar irradiation, outperforming a CeO2 photocatalyst in terms of effectiveness and rate of dye mineralization. The co-doped CeO2 photocatalyst also exhibited excellent robustness and retained its photocatalytic activity after multiple reusability tests.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Physics, Multidisciplinary
T. Gnanasekar, S. Valanarasu, Ramesh Ade, A. Vimala Juliet, V Ganesh, T. H. AlAbdulaal, Yugandhar Bitla
Summary: We investigated the co-doping effects of transition metal elements (Ni, Co) on the opto-electronic properties of CuO thin films. Our findings showed that co-doping significantly enhances the optical and electrical properties of the films.
Article
Chemistry, Multidisciplinary
Zhouhao Zhu, Hengcong Tao, Jingbin Fu, Yingtang Zhou, Jian Guo, Chunyang Zhai
Summary: Developing a convenient, fast-response, and high-performance formaldehyde detection sensor is significant but challenging. In this study, various CeO2 phases, facets, and adsorption sites were selected as substrates, and transition metals were doped on CeO2 surfaces. The results showed that the cubic fluorite structure of CeO2 and TM-CeO2(100) (TM = Au, Hf, Nb, Ta, Zr) exhibited superior abilities in adsorbing formaldehyde. The mechanism of TM-doped CeO2 improving the performance of formaldehyde adsorption was clarified using various analysis methods. This work provides theoretical guidance and experimental motivation for the development of novel formaldehyde sensors based on metal oxide semiconductor materials.
CHINESE CHEMICAL LETTERS
(2023)
Article
Chemistry, Physical
Myeong Gon Jang, Sinmyung Yoon, Dongjae Shin, Hyung Jun Kim, Rui Huang, Euiseob Yang, Jihun Kim, Kug-Seung Lee, Kwangjin An, Jeong Woo Han
Summary: In this study, the activity and selectivity of oxide-supported metal catalysts were enhanced by controlling the catalyst's facet and doping methods. The WGSR activity of Pd supported on Cu-doped CeO2 (CDC) was found to synergistically increase, exceeding the sum of the effects of morphology and Cu doping. The effect of each tuning method on the activity was further investigated from a mechanistic perspective.
Article
Materials Science, Ceramics
Chae Eun Lee, Seo Hyun Choi, Hyun Young Kim, Sun Sook Lee, Seong K. Kim, Ki-Seok An
Summary: In this study, a method to enhance the performance of cerium oxide (CeO2) based electrode materials was reported by doping Fe into CeO2 synthesized using a safe co-precipitation method. The specific capacitance of the electrode increased significantly after Fe doping, with 10FDC showing excellent cycling stability and a high specific capacitance at a high rate. This study suggests a new possibility for developing high-performance environmentally friendly energy storage materials through acceptor doping.
CERAMICS INTERNATIONAL
(2021)
Article
Nanoscience & Nanotechnology
Ounjit Sodpiban, Tanika Kessaratikoon, Jacob Smith, Guodong Ren, Silvano Del Gobbo, Sonali Das, Miaofang Chi, Valerio D'Elia, Bruce C. Gates
Summary: This study prepares atomically dispersed cerium catalysts to enhance their activity in CO oxidation reaction. By using Ce-(III) and Ce-(IV) precursors, the cerium catalysts on MgO support were successfully prepared and characterized before and after catalysis using various techniques. The results show that the excellent catalyst maintains stable activity during the 2-day reaction time and exhibits improved reducibility with the transformation of cerium ions.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Biophysics
Fang Cheng, Shenqiang Wang, Hua Zheng, Shaowei Yang, Li Zhou, Kangkai Liu, Qiuyu Zhang, Hepeng Zhang
Summary: Cu-doped cerium oxide nanoparticles loaded with doxorubicin and coated with breast cancer cell membrane were designed as a novel antitumor controlled drug release system, showing enhanced peroxidase-mimicking activity in the tumor microenvironment. This system demonstrated selective and nearly complete tumor suppression both in vitro and in vivo, while also protecting normal cells from oxidative stress.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Zhicheng Liu, Tian Zhang, Yan Lin, Hongrui Jia, Yaqun Wang, Yiyan Wang, Guoxin Zhang
Summary: Developing an inexpensive bifunctional electrocatalyst is crucial for generating scalable green hydrogen and achieving carbon neutrality. In this study, a versatile approach is proposed to synthesize highly N-doped binary FeCo-phosphides (N-FeCoP) with hierarchical superstructure, enabling enhanced water splitting electrocatalysis through high N/defect-doping, strong coupling interaction between Fe and Co components, and a 3D hierarchical superstructure. Electrochemical measurements demonstrate that N-FeCoP exhibits low overpotentials for hydrogen and oxygen evolution reactions. Remarkably, overall water splitting can be achieved on N-FeCoP using a commercial primary Zn-MnO2 battery. This synthesis strategy may inspire the development of other N-doped metal-based nanostructures for a wide range of electrocatalytic applications.
Article
Engineering, Environmental
J. Kennedy, J. Dean, I. Okeme, D. Sapsford
Summary: This study introduces the novel application of sodium carbonate dosing for the semi-passive precipitation of zinc from circum-neutral mine water. The research demonstrates that Na2CO3 can effectively precipitate zinc within environmental quality standards, achieving over 95% zinc removal for each mine drainage investigated. The use of sodium carbonate as a reagent for treating zinc-bearing mine waters could have widespread application and be advantageous due to reductions in sludge volume.
JOURNAL OF WATER PROCESS ENGINEERING
(2023)
Article
Materials Science, Ceramics
Linh T. Tr Nguyen, Khanh D. M. Nguyen, Tien A. Nguyen, Kwangsoo No
Summary: The study explored the synthesis of Zinc ferrite nanomaterial through co-precipitation method and the importance of pH in achieving pure ZnFe2O4 spinel structure. Results showed that within a pH range of 7 to 12, a single-phase spinel ferrite structure was obtained, while deviations in pH at 6 and 13 led to the appearance of unwanted phases in the product, reflecting an incomplete stoichiometric ratio.
CERAMICS INTERNATIONAL
(2022)
Article
Chemistry, Applied
Rabia Kirkgecit, Handan Ozlu Torun, Fatma Kilic Dokan, Esra Ozturk
Summary: In this research, undoped CeO2 and Ce0.85La0.10M0.05O2 (M: Sm, Er, Y) compounds were synthesized by the hydrothermal method and their multi-functional properties were investigated. The addition of rare earth ions created oxygen defects in the compounds, affecting their electrical and luminescence behaviors. Characterization techniques such as XRD, BET, UV-vis DRS, SEM, PL spectroscopy, and EIS were employed to analyze the synthesized products. The compounds were found to be nanostructured and have a cubic phase. The total conductivity and bandgap energy of the compounds were calculated, and the emission spectra showed different colors depending on the additive type.
JOURNAL OF RARE EARTHS
(2022)
Article
Chemistry, Physical
Liuxin Xu, Ya Pan, Hongmei Li, Ruichao Xu, Zhihu Sun
Summary: In this study, a La-doping strategy was proposed to enhance the water resistance of Pt-based catalysts. A Pt-CoO/Al2O3 catalyst was synthesized and tested for CO oxidation under dry conditions, showing rapid deactivation under moisture. La-doping overcame this issue and resulted in boosted activity and long-term stability.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2023)
Article
Chemistry, Physical
Joel Y. Y. Loh, Moein Shayegannia, Nazir P. Kherani
Summary: The study shows that doping with bismuth as a substitution of indium can significantly increase the CO production rate in the reverse water gas shift reaction under illumination, enhancing the photo-thermalization effect. High-doped In2O3-x(OH)(y) materials exhibit a longer persistent CO yield post-illumination, with increased yield, while low-doped and undoped systems have shorter duration and lower yield. Additionally, undoped systems show a slower decay trend in photocurrent for 1-2 hours, while high-doped systems exhibit a decay trend of more than 2 hours.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2021)
Article
Chemistry, Physical
E. Hannachi, M. Sayyed, Yassine Slimani, M. Elsafi
Summary: The widespread use of ionizing radiation has increased the demand for effective methods of reducing its risks. This study proposes the use of YBCO ceramic mixed with transition metal oxides for radiation shielding. The ceramic composites were successfully prepared and their structural and optical properties were examined. The results show that the current ceramic composites have potential for use as shielding materials against low-energy radiation.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Nanoscience & Nanotechnology
Zichen Xu, Yuanjuan Jiang, Jeng-Lung Chen, Ryan Yeh-Yung Lin
Summary: In this study, a heterostructured electrocatalyst is developed for overall water splitting. The combination of Co-FeOOH and Ir-Co(OH)F creates abundant active sites, accelerates reaction kinetics, improves charge transfer abilities, and optimizes adsorption energies, leading to enhanced catalytic activity. The electrocatalyst exhibits low overpotentials and excellent stability for OER, HER, and overall water splitting in 1.0 M KOH electrolyte. This research provides a promising strategy for advanced heterostructured bifunctional electrocatalysts in alkaline water splitting.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Neurosciences
Fayyaz Ahmad, Muqaddas Javed, Muhammad Athar, Samra Shahzadi
Summary: The study aimed to identify brain areas affected during each stage of Alzheimer's disease (AD). Six areas were affected during mild cognitive impairment, four during the first stage, and six during each of the second and third stages. The common brain regions in all stages were identified. The resting state fMRI data of 18 AD patients from the ADNI database were analyzed using independent component analysis and a deep learning convolutional neural network algorithm. The proposed CNN model achieved high accuracy in classifying the stages of AD.
NEUROSCIENCE RESEARCH
(2023)
Article
Materials Science, Multidisciplinary
Muhammad Rashid, Warda Hassan, Muhammad Aadil, H. H. Somaily, Noor Mahmood Mahdi, Rahiam Lataef, Anmar Ghanim Taki, Khaysy Srithilat, Doaa F. Baamer, Soha M. Albukhari, Mohamed Abdel Salam, Asif Llyas
Summary: Semi-conductive photocatalysts are highly efficient and cost-effective for water treatment applications. Material scientists are working on developing nanostructured Mn-doped cobalt ferrite as a magnetically recyclable photocatalytic material that is active in visible light and has high conductivity. The study investigates the crystal structure, chemical composition, functionality, and morphology of the prepared ferrite samples, as well as their thermal stability, electrical conductivity, light-harvesting capability, charge transport performance, and charge separation efficiency.
Article
Chemistry, Physical
Asma D. D. Alomari, Dalal Alezi, Mohamed Abdel Salam
Summary: A terbium-based metal-organic framework (Tb-FTZB-MOF) with high surface area was successfully synthesized and characterized. It was found to effectively remove direct violet 31 dye from both model and real solutions, with optimal conditions being ambient temperature, pH value of 8.0, and a dosage of 35 mg Tb-FTZB-MOF.
Article
Chemistry, Medicinal
Bilal Ahmad Khan, Syeda Shamila Hamdani, Saquib Jalil, Syeda Abida Ejaz, Jamshed Iqbal, Ahmed M. M. Shawky, Alaa M. M. Alqahtani, Gamal A. A. Gabr, Mahmoud A. A. Ibrahim, Peter A. A. Sidhom
Summary: New S-alkyl phthalimide and S-benzyl analogs of 5-(2-phenylquinolin-4-yl)-1,3,4-oxadiazole-2-thiol were successfully synthesized. The synthesized molecules were characterized using spectroscopic techniques. The inhibition activity of these compounds against MAO-A, MAO-B, and AChE enzymes was evaluated, and they showed submicromolar activity against all enzymes. Compounds 5a, 5f, and 5c exhibited the most potent inhibition activity and promising docking scores, making them potential candidates for the treatment of Alzheimer's disease.
Article
Biochemistry & Molecular Biology
Syeda Abida Ejaz, Mubashir Aziz, Aftab Ahmed, Saqer S. S. Alotaibi, Sarah M. M. Albogami, Farhan Siddique, Gaber El-Saber Batiha
Summary: The aim of this research is to investigate the quantum geometric properties and chemical reactivity of atropine. Computational methods were used to determine the stable geometry of atropine and calculate various molecular parameters. Molecular docking analysis showed that atropine has greater inhibitory action against AKR1B1 than AKR1B10. Simulation data and ADMET characteristics were used to predict the drug likeness of atropine. This research suggests that atropine has potential as an inhibitor of AKR1B1 for the treatment of colon cancer associated with AKR1B1 expression.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Parvez Ali Mahesar, Pervaiz Ali Channar, Syeda Abida Ejaz, Aamer Saeed, F. F. Alharbi, Tahira Shamim, Mubashir Aziz, Rabail Ujan, Ghulam Abbas Kandhro, Sajid Ali Channar, Qamar Abbas, Mumtaz Hussain
Summary: In this study, a new series of pyridine substituted 1,2,4-triazoles was synthesized and evaluated for their acetylcholinesterase (AChE) inhibition activity. Compound 5f showed the strongest inhibition activity with an IC50 value of 0.0249 μM. The kinetics mechanism studies revealed that compound 5f competitively inhibited the enzyme, and its Ki value was determined to be 0.025 μM. Molecular docking and molecular dynamics simulations supported these findings and demonstrated the stability of the protein-ligand complex. These derivatives have great potential as lead molecules for drug discovery in the management of age-related neurodegenerative diseases.
Article
Biochemistry & Molecular Biology
Bushra Bashir, Naheed Riaz, Syeda Abida Ejaz, Muhammad Saleem, Ambar Iqbal, Muhammad Ashraf, Samina Ejaz, Aziz-ur Aziz-ur-Rehman, Mubashir Aziz, Keshab Bhattarai
Summary: This study focuses on the synthesis of a new series of N-alkyl/aralkyl/aryl derivatives and their inhibiting potential against soybean 15-lipoxygenase enzyme. The compounds 7a, 7n, 7g, 7e, 7h, 7i, 7j, and 7b showed potent inhibitory activities, while compounds 7o, 7m, 7k, 7f, 7c, 7l, and 7d exhibited good inhibitory activities. Pharmacokinetic profiles indicated good oral bioavailability and drug-likeness properties of the compounds.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Chemistry, Physical
Mohamed Abdel Salam, Eman Saleem Imdadulhaq, Abeer Nasser Al-Romaizan, Tamer S. Saleh, Mohamed Mokhtar M. Mostafa
Summary: Ultrasound-assisted synthesis of novel pyrazoles using Ni-Mg-Fe LDH as a catalyst in cyclopentyl methyl ether (CPME) is described. Different LDHs were evaluated for their catalytic activity in the synthesis of pyrazoles via 1,3-dipolar cycloaddition reaction, with Ni-Mg-Fe LDH proving to be the most effective catalyst. The protocol offered high yields, short reaction time, and a green solvent, and the catalyst could be reused six times without significant loss of activity, demonstrating its eco-friendly and sustainable nature. A plausible mechanism for the reaction over the Ni-Mg-Fe LDH catalyst is proposed.
Article
Chemistry, Physical
Atteeque Ahmed, Aftab Ahmed, Pervaiz Ali Channar, Syeda Abida Ejaz, Aisha A. Alsfouk, Aamer Saeed, Rabail Ujan, Qamar Abbas, Tuncer Hokelek, Michael Bolte
Summary: Carbonic anhydrases (CAs) are widely expressed metalloenzymes that play a crucial role in various physiological and pathological processes. An alkyl substituted acyl thiourea compound was synthesized and characterized using NMR spectroscopy and single crystal X-ray diffraction. The synthesized compound showed hydrogen bonding and H···H interactions, and demonstrated inhibition of carbonic anhydrase activity. Quantum mechanical descriptors, molecular docking, and ADMET analysis were performed to analyze the compound's properties and potential as a drug inhibitor of carbonic anhydrase.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Physical
Ghulam Nazik, Muhammad Aadil, Sonia Zulfiqar, Warda Hassan, Abdur Rahman, Sobhy M. Ibrahim, Khalida Naseem, Tahir Ali Sheikh, Muhammad Nadeem Akhtar
Summary: This paper explores different techniques to improve the electrochemical sensing activities of transition metal chalcogenides. Surface-assisted nanotechnology and doping are used to enhance the properties of the materials, and graphene nanoplates are mixed to improve charge flow and stability. Physicochemical techniques are used to determine the structure and properties of the materials. The composite material shows superior surface area, conductivity, and charge transport properties, and exhibits excellent sensing activity for Pb(II) ions.
ZEITSCHRIFT FUR PHYSIKALISCHE CHEMIE-INTERNATIONAL JOURNAL OF RESEARCH IN PHYSICAL CHEMISTRY & CHEMICAL PHYSICS
(2023)
Article
Chemistry, Physical
Kashuf Shafiq, Muhammad Aadil, Warda Hassan, Qurshia Choudhry, Safia Gul, Afroz Rais, Alaa A. Fattah, Khaled H. Mahmoud, Mohd Zahid Ansari
Summary: This study reports nickel ferrite-based photocatalysts with enhanced light utilizing electrical charge transport properties. The co-doping of cobalt and holmium in the nickel ferrite nanoparticles enables the absorption of maximum wavelengths from the UV and visible regions, leading to improved photocatalytic activity. The co-doped ferrite photocatalyst also contains structural defects that act as reservoirs for charge species, preventing charge recombination and enhancing the degradation of crystal violet dye.
ZEITSCHRIFT FUR PHYSIKALISCHE CHEMIE-INTERNATIONAL JOURNAL OF RESEARCH IN PHYSICAL CHEMISTRY & CHEMICAL PHYSICS
(2023)
Article
Environmental Sciences
Carlos Villaorduna, Mariano Mendoza-Carlos, Manuel Chuyma, Jhon Aviles, Ayda Avalos-Diaz, Ronald Lozano-Reategui, Juan Garcia-Ruiz, Nadia Panduro-Tenazoa, Jessy Vargas, Ysabel Moran-Quintanilla, Jose-Luis Rodriguez
Summary: Ipconazole, an antifungal agrochemical, poses a hazard to human, animal, and environmental health due to its widespread use in agriculture and easy accumulation in the environment. Our study investigated the cytotoxic effects of ipconazole on SH-SY5Y neuroblastoma cells, revealing a dose-dependent reduction in cell viability, increased ROS production, and induction of cell death. These findings suggest that ipconazole exposure may contribute to neurotoxicity or neurodegeneration.
Article
Chemistry, Multidisciplinary
Syeda Abida Ejaz, Aftab Farid, Seema Zargar, Pervaiz Ali Channar, Mubashir Aziz, Tanveer A. Wani, Hafiz Muhammad Attaullah, Rabail Ujhan, Arfa Tehzeeb, Aamer Saeed, Hafiz Saqib Ali, Mauricio F. Erben
Summary: Energetic heterocycles, such as pyridines, triazoles, and tetrazoles, show higher density, heats of formation, and oxygen balance than their carbocyclic counterparts, making them a promising method for synthesizing novel bis-tetrazole acetamides. The analysis of synthesized compounds A-F showed their potential as valuable synthons for aryl coupling reactions. Molecular docking studies demonstrated the anti-cancer potential of the synthesized heterocyclic compounds against caspase 3, NF-KAPPA-B, and P53 protein.
Article
Chemistry, Multidisciplinary
Muhammad Naeem Mustafa, Pervaiz Ali Channar, Syeda Abida Ejaz, Saira Afzal, Mubashir Aziz, Tahira Shamim, Aamer Saeed, Aisha A. Alsfouk, Rabail Ujan, Qamar Abbas, Tuncer Hoekelek
Summary: A new compound, C23H20BrN3OS, was synthesized and its crystal and molecular structures were analyzed through single crystal X-ray analysis. The compound showed potential as a novel inhibitor of elastase enzyme, exhibiting stronger activity than oleanolic acid. Both theoretical and experimental findings suggested that this compound could have a number of biological activities.
