Superior anti-tumor activity of the MDM2 antagonist idasanutlin and the Bcl-2 inhibitor venetoclax in p53 wild-type acute myeloid leukemia models
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Title
Superior anti-tumor activity of the MDM2 antagonist idasanutlin and the Bcl-2 inhibitor venetoclax in p53 wild-type acute myeloid leukemia models
Authors
Keywords
BCL-2, MDM2, AML, Cell cycle kinetics, Apoptosis, Idasanutlin, Venetoclax, p53, MCL-1, Synergism
Journal
Journal of Hematology & Oncology
Volume 9, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-06-28
DOI
10.1186/s13045-016-0280-3
References
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