IL-10 alleviates radicular pain by inhibiting TNF-α/p65 dependent Nav1.7 up-regulation in DRG neurons of rats

Sex differences in neuroimmune and glial mechanisms of pain

(2021) Ann M. Gregus et al.   PAIN

Addressing the gender pain gap

(2021) John M. Dawes et al.   NEURON

Qualitative sex differences in pain processing: emerging evidence of a biased literature

(2020) Jeffrey S. Mogil   NATURE REVIEWS NEUROSCIENCE

Analgesic effects of calcitonin on radicular pain in male rats

(2019) Yoshinori Terashima et al.   Journal of Pain Research

SFKs/p38 Pathway is Involved in Radicular Pain by Promoting Spinal Expression of Pro-Inflammatory Cytokines in a Rat Model of Lumbar Disc Herniation

(2019) Yi Zhong et al.   SPINE

Comorbidity of Pain and Depression in a Lumbar Disc Herniation Model: Biochemical Alterations and the Effects of Fluoxetine

(2019) Lun Cai et al.   Frontiers in Neurology

Upregulation of N-type calcium channels in the soma of uninjured dorsal root ganglion neurons contributes to neuropathic pain by increasing neuronal excitability following peripheral nerve injury

(2018) Jie Yang et al.   BRAIN BEHAVIOR AND IMMUNITY

IL-33/ST2 signaling contributes to radicular pain by modulating MAPK and NF-κB activation and inflammatory mediator expression in the spinal cord in rat models of noncompressive lumber disk herniation

(2018) Si-Jian Huang et al.   Journal of Neuroinflammation

Neuroinflammation of the spinal cord and nerve roots in chronic radicular pain patients

(2018) Daniel S. Albrecht et al.   PAIN

Puerarin alleviate radicular pain from lumbar disc herniation by inhibiting ERK-dependent spinal microglia activation

(2018) Yi Zhong et al.   NEUROPEPTIDES

Src-family kinases activation in spinal microglia contributes to central sensitization and chronic pain after lumbar disc herniation

(2017) Yangliang Huang et al.   Molecular Pain

Upregulation of the sodium channel NaVβ4 subunit and its contributions to mechanical hypersensitivity and neuronal hyperexcitability in a rat model of radicular pain induced by local dorsal root ganglion inflammation

(2016) Wenrui Xie et al.   PAIN

Voltage-Gated Ion Channels in the PNS: Novel Therapies for Neuropathic Pain?

(2016) Gareth R. Tibbs et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Hyperexcitability and sensitization of sodium channels of dorsal root ganglion neurons in a rat model of lumber disc herniation

(2015) Jun Yan et al.   EUROPEAN SPINE JOURNAL

Gender Influences Radicular Pain Perception in Patients with Lumbar Disc Herniation

(2015) Anja Tschugg et al.   JOURNAL OF WOMENS HEALTH

The role of TNF-alpha/NF-kappa B pathway on the up-regulation of voltage-gated sodium channel Nav1.7 in DRG neurons of rats with diabetic neuropathy

(2014) Yangliang Huang et al.   NEUROCHEMISTRY INTERNATIONAL

Tactile allodynia in patients with lumbar radicular pain (sciatica)

(2014) Ruth Defrin et al.   PAIN

Evaluation of behavior and expression of NaV1.7 in dorsal root ganglia after sciatic nerve compression and application of nucleus pulposus in rats

(2013) Michiaki Mukai et al.   EUROPEAN SPINE JOURNAL

Interleukin-10 down-regulates voltage gated sodium channels in rat dorsal root ganglion neurons

(2013) Kai-Feng Shen et al.   EXPERIMENTAL NEUROLOGY

Randomized, Double-blind, Placebo-Controlled, Trial of Transforaminal Epidural Etanercept for the Treatment of Symptomatic Lumbar Disc Herniation

(2013) Brian J. C. Freeman et al.   SPINE

Chronic compression of mouse dorsal root ganglion alters voltage-gated sodium and potassium currents in medium-sized dorsal root ganglion neurons

(2011) Ni Fan et al.   JOURNAL OF NEUROPHYSIOLOGY

Abnormal Spontaneous Activities on Needle Electromyography and Their Relation With Pain Behavior and Nerve Fiber Pathology in a Rat Model of Lumbar Disc Herniation

(2011) Su-Jeong Kim et al.   SPINE

Sciatica

(2010) Jean-Pierre Valat et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

TNF-α enhances the currents of voltage gated sodium channels in uninjured dorsal root ganglion neurons following motor nerve injury

(2010) Xi Chen et al.   EXPERIMENTAL NEUROLOGY

TNF-α contributes to up-regulation of Nav1.3 and Nav1.8 in DRG neurons following motor fiber injury

(2010) Xin-Hua He et al.   PAIN

Gait Abnormalities and Inflammatory Cytokines in an Autologous Nucleus Pulposus Model of Radiculopathy

(2009) Mohammed F. Shamji et al.   SPINE