Induction, decay, and determinants of functional antibodies following vaccination with the RTS,S malaria vaccine in young children

Breadth of humoral immune responses to the C-terminus of the circumsporozoite protein is associated with protective efficacy induced by the RTS,S malaria vaccine

(2021) Sidhartha Chaudhury et al.   VACCINE

Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites

(2021) Gaoqian Feng et al.   Nature Communications

Multi-functional antibody profiling for malaria vaccine development and evaluation

(2021) D. Herbert Opi et al.   Expert Review of Vaccines

Seasonal Malaria Vaccination with or without Seasonal Malaria Chemoprevention

(2021) Daniel Chandramohan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neutrophils dominate in opsonic phagocytosis of P. falciparum blood-stage merozoites and protect against febrile malaria

(2021) Asier Garcia-Senosiain et al.   Communications Biology

Antibody Targets and Properties for Complement-Fixation Against the Circumsporozoite Protein in Malaria Immunity

(2021) Liriye Kurtovic et al.   Frontiers in Immunology

There Is (Scientific) Strength in Numbers: A Comprehensive Quantitation of Fc Gamma Receptor Numbers on Human and Murine Peripheral Blood Leukocytes

(2020) Christina Kerntke et al.   Frontiers in Immunology

Multifunctional Antibodies Are Induced by the RTS,S Malaria Vaccine and Associated With Protection in a Phase 1/2a Trial

(2020) Liriye Kurtovic et al.   JOURNAL OF INFECTIOUS DISEASES

Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination

(2020) Todd J. Suscovich et al.   Science Translational Medicine

Challenges and strategies for developing efficacious and long-lasting malaria vaccines

(2019) James G. Beeson et al.   Science Translational Medicine

Induction and decay of functional complement-fixing antibodies by the RTS,S malaria vaccine in children, and a negative impact of malaria exposure

(2019) Liriye Kurtovic et al.   BMC Medicine

Concentration and avidity of antibodies to different circumsporozoite epitopes correlate with RTS,S/AS01E malaria vaccine efficacy

(2019) Carlota Dobaño et al.   Nature Communications

Human antibodies activate complement against Plasmodium falciparum sporozoites, and are associated with protection against malaria in children

(2018) Liriye Kurtovic et al.   BMC Medicine

RTS,S malaria vaccine efficacy and immunogenicity during Plasmodium falciparum challenge is associated with HLA genotype

(2018) C.M. Nielsen et al.   VACCINE

Baseline exposure, antibody subclass, and hepatitis B response differentially affect malaria protective immunity following RTS,S/AS01E vaccination in African children

(2018) Itziar Ubillos et al.   BMC Medicine

Antibody-Mediated Protection against Plasmodium Sporozoites Begins at the Dermal Inoculation Site

(2018) Yevel Flores-Garcia et al.   mBio

Neutrophils and Malaria

(2018) Elizabeth H. Aitken et al.   Frontiers in Immunology

Structural basis for antibody recognition of the NANP repeats inPlasmodium falciparumcircumsporozoite protein

(2017) David Oyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Opsonic Phagocytosis Assay for Plasmodium falciparum Sporozoites

(2016) Ryan W. J. Steel et al.   Clinical and Vaccine Immunology

Dimeric FcγR Ectodomains as Probes of the Fc Receptor Function of Anti-Influenza Virus IgG

(2016) Bruce D. Wines et al.   JOURNAL OF IMMUNOLOGY

The biological function of antibodies induced by the RTS,S/AS01 malaria vaccine candidate is determined by their fine specificity

(2016) Sidhartha Chaudhury et al.   MALARIA JOURNAL

Seven-Year Efficacy of RTS,S/AS01 Malaria Vaccine among Young African Children

(2016) Ally Olotu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial

(2015)   LANCET

Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial

(2015) Michael T White et al.   LANCET INFECTIOUS DISEASES

Molecular properties of human IgG subclasses and their implications for designing therapeutic monoclonal antibodies against infectious diseases

(2015) Vashti Irani et al.   MOLECULAR IMMUNOLOGY

Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine

(2015) Daniel E. Neafsey et al.   NEW ENGLAND JOURNAL OF MEDICINE

Opsonic phagocytosis of Plasmodium falciparummerozoites: mechanism in human immunity and a correlate of protection against malaria

(2014) Faith HA Osier et al.   BMC Medicine

Duration of vaccine efficacy against malaria: 5th year of follow-up in children vaccinated with RTS,S/AS02 in Mozambique

(2014) Joseph J. Campo et al.   VACCINE

Efficacy and Safety of the RTS,S/AS01 Malaria Vaccine during 18 Months after Vaccination: A Phase 3 Randomized, Controlled Trial in Children and Young Infants at 11 African Sites

(2014)   PLOS MEDICINE

Vaccine-induced monoclonal antibodies targeting circumsporozoite protein prevent Plasmodium falciparum infection

(2013) Lander Foquet et al.   JOURNAL OF CLINICAL INVESTIGATION

Full-Length Plasmodium falciparum Circumsporozoite Protein Administered with Long-Chain Poly(I·C) or the Toll-Like Receptor 4 Agonist Glucopyranosyl Lipid Adjuvant-Stable Emulsion Elicits Potent Antibody and CD4+T Cell Immunity and Protection in Mice

(2012) Kathrin Kastenmüller et al.   INFECTION AND IMMUNITY

Chronic Exposure to Plasmodium falciparum Is Associated with Phenotypic Evidence of B and T Cell Exhaustion

(2012) J. Illingworth et al.   JOURNAL OF IMMUNOLOGY

Safety and efficacy of the RTS,S/AS01 E candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised, open-label, phase 2 trial

(2011) Kwaku Poku Asante et al.   LANCET INFECTIOUS DISEASES

First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Nomenclature of monocytes and dendritic cells in blood

(2010) L. Ziegler-Heitbrock et al.   BLOOD

Using an Improved Phagocytosis Assay to Evaluate the Effect of HIV on Specific Antibodies to Pregnancy-Associated Malaria

(2010) Ricardo Ataíde et al.   PLoS One

The RTS,S malaria vaccine

(2010) Sofia Casares et al.   VACCINE

Efficacy of RTS,S/AS01E Vaccine against Malaria in Children 5 to 17 Months of Age

(2008) Philip Bejon et al.   NEW ENGLAND JOURNAL OF MEDICINE