Danhong injection combined with tPA protects the BBB through Notch-VEGF signaling pathway on long-term outcomes of thrombolytic therapy

Nogo-B promotes angiogenesis and improves cardiac repair after myocardial infarction via activating Notch1 signaling

(2022) Yanjun Zheng et al.   Cell Death & Disease

Notch signalling in healthy and diseased vasculature

(2022) Francesca Del Gaudio et al.   Open Biology

The Prognostic Role and Significance of Dll4 and Toll-like Receptors in Cancer Development

(2022) Zacharias Fasoulakis et al.   Cancers

Notch Signaling in Vascular Endothelial Cells, Angiogenesis, and Tumor Progression: An Update and Prospective

(2021) Abdellah Akil et al.   Frontiers in Cell and Developmental Biology

Efficacy and Safety of TCMI in Patients With Combined Coronary Heart Disease and Heart Failure: A Systematic Review and Network Meta-Analysis

(2021) Penglu Wei et al.   Frontiers in Pharmacology

Pharmacological potential of the combination of Salvia miltiorrhiza (Danshen) and Carthamus tinctorius (Honghua) for diabetes mellitus and its cardiovascular complications

(2020) John O. Orgah et al.   PHARMACOLOGICAL RESEARCH

Neuroprotective Effect of Danhong Injection on Cerebral Ischemia-Reperfusion Injury in Rats by Activation of the PI3K-Akt Pathway

(2020) Chen Feng et al.   Frontiers in Pharmacology

Danhong Injection Protects Hemorrhagic Brain by Increasing Peroxiredoxin 1 in Aged Rats

(2020) Shang Wang et al.   Frontiers in Pharmacology

Slug regulates the Dll4-Notch-VEGFR2 axis to control endothelial cell activation and angiogenesis

(2020) Nan W. Hultgren et al.   Nature Communications

NOTCH signalling in ovarian cancer angiogenesis

(2020) Jose Alejandro Perez-Fidalgo et al.   Annals of Translational Medicine

The Notch pathway: a novel therapeutic target for cardiovascular diseases?

(2019) Giorgio Aquila et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Notch Signaling in Osteogenesis, Osteoclastogenesis, and Angiogenesis

(2019) Zhengliang Luo et al.   AMERICAN JOURNAL OF PATHOLOGY

Danhong Injection Combined With t-PA Improves Thrombolytic Therapy in Focal Embolic Stroke

(2018) Min Li et al.   Frontiers in Pharmacology

Danhong injection in cardiovascular and cerebrovascular diseases: Pharmacological actions, molecular mechanisms, and therapeutic potential

(2018) Xiaojun Feng et al.   PHARMACOLOGICAL RESEARCH

The emerging role of Notch pathway in ageing: Focus on the related mechanisms in age-related diseases

(2016) Carmela Rita Balistreri et al.   AGEING RESEARCH REVIEWS

Effects of Danhong Injection (丹红注射液) and its main components on anticoagulation and fibrinolysis in cultured vein endothelial cells

(2016) Yu-yan Zhang et al.   Chinese Journal of Integrative Medicine

Targeting Notch degradation system provides promise for breast cancer therapeutics

(2016) Jing Liu et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Regional extravasation of Evans blue dye in the brain across the blood-brain barrier during cerebral hypoperfusion

(2016) Sekaran Hema et al.   Frontiers in Cellular Neuroscience

Notch Signaling in Neuroendocrine Tumors

(2016) Judy S. Crabtree et al.   Frontiers in Oncology

DanHong injection dose-dependently varies amino acid metabolites and metabolic pathways in the treatment of rats with cerebral ischemia

(2015) Zhi-li Guo et al.   ACTA PHARMACOLOGICA SINICA

Blood–brain barrier dysfunction following traumatic brain injury

(2015) Himakarnika Alluri et al.   METABOLIC BRAIN DISEASE

Transmembrane proteins of the tight junctions at the blood–brain barrier: Structural and functional aspects

(2015) Reiner F. Haseloff et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Alteplase Reduces Downstream Microvascular Thrombosis and Improves the Benefit of Large Artery Recanalization in Stroke

(2015) Jean-Philippe Desilles et al.   STROKE

Markers for blood-brain barrier integrity: how appropriate is Evans blue in the twenty-first century and what are the alternatives?

(2015) Norman R. Saunders et al.   Frontiers in Neuroscience

Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials

(2014) Jonathan Emberson et al.   LANCET

Danhong Injection Attenuates Ischemia/Reperfusion-Induced Brain Damage Which is Associating with Nrf2 Levels In Vivo and In Vitro

(2014) Hong Guo et al.   NEUROCHEMICAL RESEARCH

A novel multi-target ligand (JM-20) protects mitochondrial integrity, inhibits brain excitatory amino acid release and reduces cerebral ischemia injury in vitro and in vivo

(2014) Yanier Nuñez-Figueredo et al.   NEUROPHARMACOLOGY

Melittin enhances radiosensitivity of hypoxic head and neck squamous cell carcinoma by suppressing HIF-1α

(2014) Xi Yang et al.   TUMOR BIOLOGY

Off-label thrombolysis versus full adherence to the current European Alteplase license: impact on early clinical outcomes after acute ischemic stroke

(2013) Manuel Cappellari et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Hypoxia, notch signalling and prostate cancer

(2013) Laure Marignol et al.   Nature Reviews Urology

Evidence that collaboration between HIF-1α and Notch-1 promotes neuronal cell death in ischemic stroke

(2013) Yi-Lin Cheng et al.   NEUROBIOLOGY OF DISEASE

Vascular remodeling after ischemic stroke: Mechanisms and therapeutic potentials

(2013) Jialing Liu et al.   PROGRESS IN NEUROBIOLOGY

Effects of Tissue Plasminogen Activator and Annexin A2 Combination Therapy on Long-Term Neurological Outcomes of Rat Focal Embolic Stroke

(2013) Xiaoshu Wang et al.   STROKE

VEGF and Notch in Tip and Stalk Cell Selection

(2013) R. Blanco et al.   Cold Spring Harbor Perspectives in Medicine

Protective effect of Danhong injection on cerebral ischemia–reperfusion injury in rats

(2012) Yu He et al.   JOURNAL OF ETHNOPHARMACOLOGY

Prognostic significance of vascular endothelial growth factor expression in adult patients with acute myeloid leukemia: a meta-analysis

(2012) Baoping Guo et al.   LEUKEMIA & LYMPHOMA

Blood-brain barrier, reperfusion injury, and hemorrhagic transformation in acute ischemic stroke

(2012) R. Khatri et al.   NEUROLOGY

Thrombolysis with Alteplase 4.5–6 Hours after Acute Ischemic Stroke

(2011) Bin Zhang et al.   EUROPEAN NEUROLOGY

Recombinant Human Angiopoietin-1 Ameliorates the Expressions of ZO-1, Occludin, VE-cadherin, and PKCα Signaling after Focal Cerebral Ischemia/Reperfusion in Rats

(2011) Hang Yu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Specific Role of Tight Junction Proteins Claudin-5, Occludin, and ZO-1 of the Blood–Brain Barrier in a Focal Cerebral Ischemic Insult

(2011) Haixia Jiao et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Caveolin-1 regulates nitric oxide-mediated matrix metalloproteinases activity and blood-brain barrier permeability in focal cerebral ischemia and reperfusion injury

(2011) Yong Gu et al.   JOURNAL OF NEUROCHEMISTRY

Dynamics of endothelial cell behavior in sprouting angiogenesis

(2010) Hanna M Eilken et al.   CURRENT OPINION IN CELL BIOLOGY

Annexin A2 Combined with Low-Dose tPA Improves Thrombolytic Therapy in a Rat Model of Focal Embolic Stroke

(2010) Haihao Zhu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Implementation and outcome of thrombolysis with alteplase 3–4·5 h after an acute stroke: an updated analysis from SITS-ISTR

(2010) Niaz Ahmed et al.   LANCET NEUROLOGY

Red blood cell-coupled tissue plasminogen activator prevents impairment of cerebral vasodilatory responses through inhibition of c-Jun-N-terminal kinase and potentiation of p38 mitogen-activated protein kinase after cerebral photothrombosis in the newborn pig

(2010) William M. Armstead et al.   Pediatric Critical Care Medicine

The Notch Ligands Dll4 and Jagged1 Have Opposing Effects on Angiogenesis

(2009) Rui Benedito et al.   CELL

Wnt/Notch signalling and information processing during development

(2008) P. Hayward et al.   DEVELOPMENT

Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke

(2008) Werner Hacke et al.   NEW ENGLAND JOURNAL OF MEDICINE

Thrombolysis with alteplase for acute ischemic stroke: safe and effective outside the 3-hour time window?

(2008) Thomas WH Leung et al.   Nature clinical practice. Neurology