Cytostatic effects of structurally different ginsenosides on yeast cells with altered sterol biosynthesis and transport

Maintaining symbiotic homeostasis: how do plants engage with beneficial microorganisms while at the same time restricting pathogens?

(2021) David Thoms et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

The Candida glabrata Upc2A transcription factor is a global regulator of antifungal drug resistance pathways

(2021) Bao Gia Vu et al.   PLoS Genetics

LAM Genes Contribute to Environmental Stress Tolerance but Sensibilize Yeast Cells to Azoles

(2020) Svyatoslav S. Sokolov et al.   Frontiers in Microbiology

Comparative assessment of purified saponins as permeabilization agents during respirometry

(2020) Corinna Dawid et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Lipid Membranes as Key Targets for the Pharmacological Actions of Ginsenosides

(2020) Sandrine L. Verstraeten et al.   Frontiers in Pharmacology

Do Multiple Drug Resistance Transporters Interfere with Cell Functioning under Normal Conditions?

(2020) D. A. Knorre et al.   BIOCHEMISTRY-MOSCOW

Ergosterol Turnover in Yeast: An Interplay between Biosynthesis and Transport

(2019) S. S. Sokolov et al.   BIOCHEMISTRY-MOSCOW

Regulation of targeting determinants in interorganelle communication

(2019) Ganiyu O Alli-Balogun et al.   CURRENT OPINION IN CELL BIOLOGY

The activity of the saponin ginsenoside Rh2 is enhanced by the interaction with membrane sphingomyelin but depressed by cholesterol

(2019) Sandrine L. Verstraeten et al.   Scientific Reports

The wide‐ranging phenotypes of ergosterol biosynthesis mutants, and implications for microbial cell factories

(2019) Emily J. Johnston et al.   YEAST

Molecular basis for sterol transport by StART‐like lipid transfer domains

(2018) Florian A Horenkamp et al.   EMBO JOURNAL

TOR Complex 2-regulated protein kinase Ypk1 controls sterol distribution by inhibiting StARkin domain-containing proteins located at plasma membrane-endoplasmic reticulum contact sites

(2018) Françoise M. Roelants et al.   MOLECULAR BIOLOGY OF THE CELL

Identification of candidate UDP-glycosyltransferases involved in protopanaxadiol-type ginsenoside biosynthesis in Panax ginseng

(2018) Kyo Bin Kang et al.   Scientific Reports

Antifungal activity and mechanism of heat-transformed ginsenosides from notoginseng against Epidermophyton floccosum, Trichophyton rubrum, and Trichophyton mentagrophytes

(2017) Peng Xue et al.   RSC Advances

Lipid transfer proteins do their thing anchored at membrane contact sites… but what is their thing?

(2016) Louise H. Wong et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Modeling Yeast Organelle Membranes and How Lipid Diversity Influences Bilayer Properties

(2015) Viviana Monje-Galvan et al.   BIOCHEMISTRY

Structural mechanism of ergosterol regulation by fungal sterol transcription factor Upc2

(2015) Huiseon Yang et al.   Nature Communications

A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport

(2015) Alberto T Gatta et al.   eLife

Mechanistic Investigation of Interactions between Steroidal Saponin Digitonin and Cell Membrane Models

(2014) Nataliya Frenkel et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Induction of Highly Curved Structures in Relation to Membrane Permeabilization and Budding by the Triterpenoid Saponins, α- and δ-Hederin

(2013) Joseph Lorent et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Studies on the interactions between ginsenosides and liposome by equilibrium dialysis combined with ultrahigh performance liquid chromatography-tandem mass spectrometry

(2013) Guangyue Hou et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

CHARMM36 all-atom additive protein force field: Validation based on comparison to NMR data

(2013) Jing Huang et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Saponins can perturb biologic membranes and reduce the surface tension of aqueous solutions: A correlation?

(2012) Stefan Böttger et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Bioavailability Challenges Associated with Development of Saponins As Therapeutic and Chemopreventive Agents

(2012) Song Gao et al.   CURRENT DRUG TARGETS

The production of ginsenosides in hairy root cultures of American Ginseng, Panax quinquefolium L. and their antimicrobial activity

(2012) Ewa Kochan et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-PLANT

Fungal sensitivity to and enzymatic deglycosylation of ginsenosides

(2012) Xuesong Zhao et al.   PHYTOCHEMISTRY

Enhancement of Oral Bioavailability of 20(S)-Ginsenoside Rh2 through Improved Understanding of Its Absorption and Efflux Mechanisms

(2011) Z. Yang et al.   DRUG METABOLISM AND DISPOSITION

Steroid-transforming enzymes in fungi

(2011) Katja Kristan et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Repression of ergosterol biosynthesis is essential for stress resistance and is mediated by the Hog1 MAP kinase and the Mot3 and Rox1 transcription factors

(2010) Fernando Martínez Montañés et al.   MOLECULAR MICROBIOLOGY

Ginsenoside Rh2 induces ligand-independent Fas activation via lipid raft disruption

(2009) Jae-Sung Yi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Functional Interactions between Sphingolipids and Sterols in Biological Membranes Regulating Cell Physiology

(2009) Xue Li Guan et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanistic role of ergosterol in membrane rigidity and cycloheximide resistance in Saccharomyces cerevisiae

(2008) Fumiyoshi Abe et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Study on ginsenosides in different parts and ages of Panax quinquefolius L.

(2008) Chenling Qu et al.   FOOD CHEMISTRY