The selenocysteine toolbox: A guide to studying the 21st amino acid

Expressed Protein Selenoester Ligation

(2022) Sameer S. Kulkarni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The expression of essential selenoproteins during development requires SECIS-binding protein 2–like

(2022) Nora T Kiledjian et al.   Life Science Alliance

Integrated Top-Down and Bottom-Up Mass Spectrometry for Characterization of Diselenide Bridging Patterns of Synthetic Selenoproteins

(2022) Eleanor Watts et al.   ANALYTICAL CHEMISTRY

Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon

(2022) Tarek Hilal et al.   SCIENCE

Site‐specific selenocysteine incorporation into proteins by genetic engineering

(2021) Yuchuan Wang et al.   CHEMBIOCHEM

Selenoproteome Expression Studied by Non-Radioactive Isotopic Selenium-Labeling in Human Cell Lines

(2021) Jordan Sonet et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Intein-based Design Expands Diversity of Selenocysteine Reporters

(2021) Christina Z. Chung et al.   JOURNAL OF MOLECULAR BIOLOGY

Acetylated Thioredoxin Reductase 1 Resists Oxidative Inactivation

(2021) David. E. Wright et al.   Frontiers in Chemistry

Production and purification of homogenous recombinant human selenoproteins reveals a unique codon skipping event in E. coli and GPX4-specific affinity to bromosulfophthalein

(2021) Qing Cheng et al.   Redox Biology

Generation of Recombinant Mammalian Selenoproteins through Genetic Code Expansion with Photocaged Selenocysteine

(2020) Jennifer C. Peeler et al.   ACS Chemical Biology

Naturally Occurring tRNAs With Non-canonical Structures

(2020) Natalie Krahn et al.   Frontiers in Microbiology

Cell‐free synthesis of selenoproteins in high yield and purity for selective protein tagging

(2020) Adarshi P. Welegedara et al.   CHEMBIOCHEM

Selenoprotein M promotes hypothalamic leptin signaling and thioredoxin antioxidant activity

(2019) Ting Gong et al.   ANTIOXIDANTS & REDOX SIGNALING

Selenium–Fascinating Microelement, Properties and Sources in Food

(2019) Marek Kieliszek   MOLECULES

Chemical Biology Approaches to Interrogate the Selenoproteome

(2019) Jennifer C. Peeler et al.   ACCOUNTS OF CHEMICAL RESEARCH

Selenocysteine Substitution in a Class I Ribonucleotide Reductase

(2019) Brandon L. Greene et al.   BIOCHEMISTRY

Bioluminescence Imaging of Selenocysteine in Vivo with a Highly Sensitive Probe

(2019) Ling Zhang et al.   ACS Sensors

Detection of Selenocysteine with a Ratiometric near-Infrared Fluorescent Probe in Cells and in Mice Thyroid Diseases Model

(2019) Xianzhu Luo et al.   ANALYTICAL CHEMISTRY

A Facile Method for Producing Selenocysteine-Containing Proteins

(2018) Takahito Mukai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Site-Specific Incorporation of Selenocysteine by Genetic Encoding as a Photocaged Unnatural Amino Acid

(2018) Adarshi P. Welegedara et al.   BIOCONJUGATE CHEMISTRY

Synthesis and semisynthesis of selenopeptides and selenoproteins

(2018) Jun Liu et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Rapid and selective detection of selenocysteine with a known readily available colorimetric and fluorescent turn-on probe

(2018) Haiyan Zhang et al.   DYES AND PIGMENTS

Site-Specific Incorporation of Selenocysteine Using an Expanded Genetic Code and Palladium-Mediated Chemical Deprotection

(2018) Jun Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Custom selenoprotein production enabled by laboratory evolution of recoded bacterial strains

(2018) Ross Thyer et al.   NATURE BIOTECHNOLOGY

The interaction of selenoprotein F (SELENOF) with retinol dehydrogenase 11 (RDH11) implied a role of SELENOF in vitamin A metabolism

(2018) Jing Tian et al.   Nutrition & Metabolism

Selenium-Encoded Isotopic Signature Targeted Profiling

(2018) Jinjun Gao et al.   ACS Central Science

The Selenium Transport Protein, Selenoprotein P, Requires Coding Sequence Determinants to Promote Efficient Selenocysteine Incorporation

(2018) Sumangala P. Shetty et al.   JOURNAL OF MOLECULAR BIOLOGY

Selenocysteine Insertion at a Predefined UAG Codon in a Release Factor 1 (RF1)-depletedEscherichia coliHost Strain Bypasses Species Barriers in Recombinant Selenoprotein Translation

(2017) Qing Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Utilizing Selenocysteine for Expressed Protein Ligation and Bioconjugations

(2017) Jun Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Accessing human selenoproteins through chemical protein synthesis

(2017) L. Dery et al.   Chemical Science

Selenophosphate synthetase 1 (SPS1) is required for the development and selenium homeostasis of central nervous system in chicken (Gallus gallus)

(2017) Jin-Long Li et al.   Oncotarget

Efficient Expression of Glutathione Peroxidase with Chimeric tRNA in Amber-less Escherichia coli

(2017) Zhenlin Fan et al.   ACS Synthetic Biology

Accelerated Protein Synthesis via One-Pot Ligation-Deselenization Chemistry

(2017) Nicholas J. Mitchell et al.   Chem

Why Nature Chose Selenium

(2016) Hans J. Reich et al.   ACS Chemical Biology

A far-red fluorescent protein evolved from a cyanobacterial phycobiliprotein

(2016) Erik A Rodriguez et al.   NATURE METHODS

Biosynthetic selenoproteins with genetically-encoded photocaged selenocysteines

(2015) Rasa Rakauskaitė et al.   CHEMICAL COMMUNICATIONS

Construction of a Near-Infrared Fluorescent Turn-On Probe for Selenol and Its Bioimaging Application in Living Animals

(2015) Hua Chen et al.   CHEMISTRY-A EUROPEAN JOURNAL

A synthetic tRNA for EF-Tu mediated selenocysteine incorporationin vivoandin vitro

(2015) Corwin Miller et al.   FEBS LETTERS

Selective Selenol Fluorescent Probes: Design, Synthesis, Structural Determinants, and Biological Applications

(2015) Baoxin Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly sensitive and selective detection of biothiols by a new low dose colorimetric and fluorescent probe

(2015) Qiong Zhang et al.   RSC Advances

Intrinsic Expression of a Multiexon Type 3 Deiodinase Gene Controls Zebrafish Embryo Size

(2014) Cuicui Guo et al.   ENDOCRINOLOGY

Evolving tRNASec for Efficient Canonical Incorporation of Selenocysteine

(2014) Ross Thyer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Engineering the elongation factor Tu for efficient selenoprotein synthesis

(2014) Ken-ichi Haruna et al.   NUCLEIC ACIDS RESEARCH

Selenoproteins: Molecular Pathways and Physiological Roles

(2014) Vyacheslav M. Labunskyy et al.   PHYSIOLOGICAL REVIEWS

The SBP2 protein central to selenoprotein synthesis contacts the human ribosome at expansion segment 7L of the 28S rRNA

(2014) O. Kossinova et al.   RNA

Selenocysteine Confers Resistance to Inactivation by Oxidation in Thioredoxin Reductase: Comparison of Selenium and Sulfur Enzymes

(2013) Gregg W. Snider et al.   BIOCHEMISTRY

Contribution of Selenocysteine to the Peroxidase Activity of Selenoprotein S

(2013) Jun Liu et al.   BIOCHEMISTRY

The Intrinsically Disordered Membrane Protein Selenoprotein S Is a Reductase in Vitro

(2013) Jun Liu et al.   BIOCHEMISTRY

Recent progress in the development of near-infrared fluorescent probes for bioimaging applications

(2013) Zhiqian Guo et al.   CHEMICAL SOCIETY REVIEWS

Synthesis and decoding of selenocysteine and human health

(2013) Rachel L. Schmidt et al.   CROATIAN MEDICAL JOURNAL

Different Forms of Selenoprotein M Differentially Affect Aβ Aggregation and ROS Generation

(2013) Ping Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Expression and characterization of recombinant human phospholipid hydroperoxide glutathione peroxidase

(2013) Xiao Han et al.   IUBMB LIFE

Reconstitution of Selenocysteine Incorporation Reveals Intrinsic Regulation by SECIS Elements

(2013) Nirupama Gupta et al.   JOURNAL OF MOLECULAR BIOLOGY

Chemical Methods for Peptide and Protein Production

(2013) Saranya Chandrudu et al.   MOLECULES

SelenoDB 2.0: annotation of selenoprotein genes in animals and their genetic diversity in humans

(2013) Frédéric Romagné et al.   NUCLEIC ACIDS RESEARCH

Wobble decoding by the Escherichia coli selenocysteine insertion machinery

(2013) J. Xu et al.   NUCLEIC ACIDS RESEARCH

SECISearch3 and Seblastian: new tools for prediction of SECIS elements and selenoproteins

(2013) Marco Mariotti et al.   NUCLEIC ACIDS RESEARCH

Decameric SelAbullettRNASec Ring Structure Reveals Mechanism of Bacterial Selenocysteine Formation

(2013) Y. Itoh et al.   SCIENCE

Genomically Recoded Organisms Expand Biological Functions

(2013) M. J. Lajoie et al.   SCIENCE

Rewiring Translation for Elongation Factor Tu-Dependent Selenocysteine Incorporation

(2012) Caroline Aldag et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Characterization of selenium-containing glutathione transferase zeta1-1 with high GPX activity prepared in eukaryotic cells

(2012) Li Yin et al.   JOURNAL OF MOLECULAR RECOGNITION

Engineered rRNA Enhances the Efficiency of Selenocysteine Incorporation during Translation

(2012) Ross Thyer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Expression of selenocysteine-containing glutathione S-transferase in eukaryote

(2012) Huijuan Liu et al.   PROTEIN EXPRESSION AND PURIFICATION

Thiol Reactive Probes and Chemosensors

(2012) Hanjing Peng et al.   SENSORS

Reduced Utilization of Selenium by Naked Mole Rats Due to a Specific Defect in GPx1 Expression

(2011) Marina V. Kasaikina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Highly Efficient and More Generalcis- andtrans-Splicing Inteins through Sequential Directed Evolution

(2011) Julia H. Appleby-Tagoe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selenoprofiles: profile-based scanning of eukaryotic genome sequences for selenoprotein genes

(2010) M. Mariotti et al.   BIOINFORMATICS

Selenoproteins—What unique properties can arise with selenocysteine in place of cysteine?

(2010) Elias S.J. Arnér   EXPERIMENTAL CELL RESEARCH

Quantitative reactivity profiling predicts functional cysteines in proteomes

(2010) Eranthie Weerapana et al.   NATURE

An anaerobic bacterial MsrB model reveals catalytic mechanisms, advantages, and disadvantages provided by selenocysteine and cysteine in reduction of methionine-R-sulfoxide

(2008) Tae-Hyung Lee et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

SelenoDB 1.0 : a database of selenoprotein genes, proteins and SECIS elements

(2008) Sergi Castellano et al.   NUCLEIC ACIDS RESEARCH