Selenium status and type 2 diabetes risk

SELENOF is a new tumor suppressor in breast cancer

(2022) Alexandra Zigrossi et al.   ONCOGENE

Dietary Selenium Requirement for the Prevention of Glucose Intolerance and Insulin Resistance in Middle-Aged Mice

(2021) Ying-Chen Huang et al.   JOURNAL OF NUTRITION

A systematic review and dose-response meta-analysis of exposure to environmental selenium and the risk of type 2 diabetes in nonexperimental studies

(2021) Marco Vinceti et al.   ENVIRONMENTAL RESEARCH

Hepatic Proteomic Analysis of Selenoprotein T Knockout Mice by TMT: Implications for the Role of Selenoprotein T in Glucose and Lipid Metabolism

(2021) Ke Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Therapeutic opportunities for pancreatic β-cell ER stress in diabetes mellitus

(2021) Jing Yong et al.   Nature Reviews Endocrinology

Loss of Selenov predisposes mice to extra fat accumulation and attenuated energy expenditure

(2021) Ling-Li Chen et al.   Redox Biology

Female Mice with Selenocysteine tRNA Deletion in Agrp Neurons Maintain Leptin Sensitivity and Resist Weight Gain While on a High-Fat Diet

(2021) Daniel J. Torres et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Delivery of therapeutic agents and cells to pancreatic islets: Towards a new era in the treatment of diabetes

(2021) Elnaz Zeynaloo et al.   MOLECULAR ASPECTS OF MEDICINE

Selenium, copper, zinc and hypertension: an analysis of the National Health and Nutrition Examination Survey (2011–2016)

(2020) Mrigendra M. Bastola et al.   BMC Cardiovascular Disorders

Selenoprotein P as Biomarker of Selenium Status in Clinical Trials with Therapeutic Dosages of Selenite

(2020) Ola Brodin et al.   Nutrients

Selenoprotein F knockout leads to glucose and lipid metabolism disorders in mice

(2020) Xiaoxiang Zheng et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Gene Set Enrichment Analysis of Selenium-Deficient and High-Selenium Rat Liver Transcript Expression and Comparison With Turkey Liver Expression

(2020) Roger A Sunde   JOURNAL OF NUTRITION

Revisiting Selenium Toxicity

(2020) Wen-Hsing Cheng   JOURNAL OF NUTRITION

Thyroid Dysfunction and Diabetes Mellitus : Two Closely Associated Disorders

(2019) Bernadette Biondi et al.   ENDOCRINE REVIEWS

SELENON (SEPN1) protects skeletal muscle from saturated fatty acid-induced ER stress and insulin resistance

(2019) Ersilia Varone et al.   Redox Biology

Selenoprotein W Deficiency Does Not Affect Oxidative Stress and Insulin Sensitivity in the Skeletal Muscle of High-fat Diet-fed Obese Mice

(2019) Min-Gyeong Shin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

SBP2 deficiency in adipose tissue macrophages drives insulin resistance in obesity

(2019) Ning Wang et al.   Science Advances

Comparison of Human Selenoprotein P Determinants in Serum between Our Original Methods and Commercially Available Kits

(2018) Yoshiro Saito et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis

(2018) Irina Ingold et al.   CELL

Endoplasmic reticulum-resident selenoproteins as regulators of calcium signaling and homeostasis

(2018) Matthew W. Pitts et al.   CELL CALCIUM

Effect of long-term selenium supplementation on mortality: Results from a multiple-dose, randomised controlled trial

(2018) Margaret P. Rayman et al.   FREE RADICAL BIOLOGY AND MEDICINE

Relationship between selenoprotein P and selenocysteine lyase: Insights into selenium metabolism

(2018) Lucia A. Seale et al.   FREE RADICAL BIOLOGY AND MEDICINE

Beneficial and paradoxical roles of selenium at nutritional levels of intake in healthspan and longevity

(2018) Li Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Adipocyte DIO2 Expression Increases in Human Obesity but Is Not Related to Systemic Insulin Sensitivity

(2018) David Bradley et al.   Journal of Diabetes Research

Glutathione peroxidase 1 Pro198Leu variant contributes to the metabolic syndrome in men in a large Japanese cohort

(2018) Masafumi Kuzuya et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration

(2018) Li Zhang et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Association of genetic polymorphisms of SelS with Type 2 diabetes in a Chinese population

(2018) Long Zhao et al.   BIOSCIENCE REPORTS

Serum selenoprotein P, but not selenium, predicts future hyperglycemia in a general Japanese population

(2018) Swe Mar Oo et al.   Scientific Reports

Analyses of Selenotranscriptomes and Selenium Concentrations in Response to Dietary Selenium Deficiency and Age Reveal Common and Distinct Patterns by Tissue and Sex in Telomere-Dysfunctional Mice

(2017) Lei Cao et al.   JOURNAL OF NUTRITION

Selenoprotein P-neutralizing antibodies improve insulin secretion and glucose sensitivity in type 2 diabetes mouse models

(2017) Yuichiro Mita et al.   Nature Communications

Nrf2 Improves Leptin and Insulin Resistance Provoked by Hypothalamic Oxidative Stress

(2017) Yoko Yagishita et al.   Cell Reports

Opposing impacts on healthspan and longevity by limiting dietary selenium in telomere dysfunctional mice

(2016) Ryan T. Wu et al.   AGING CELL

Selenoprotein T Exerts an Essential Oxidoreductase Activity That Protects Dopaminergic Neurons in Mouse Models of Parkinson's Disease

(2016) Loubna Boukhzar et al.   ANTIOXIDANTS & REDOX SIGNALING

Type 3 Deiodinase Role on Central Thyroid Hormone Action Affects the Leptin-Melanocortin System and Circadian Activity

(2016) Zhaofei Wu et al.   ENDOCRINOLOGY

Selenium Supplementation for Prevention of Colorectal Adenomas and Risk of Associated Type 2 Diabetes

(2016) Patricia A. Thompson et al.   JNCI-Journal of the National Cancer Institute

Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications

(2016) Xin Gen Lei et al.   PHYSIOLOGICAL REVIEWS

TheType 2 Deiodinase Thr92Ala PolymorphismIs Associated with Worse Glycemic Control in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis

(2016) Xiaowen Zhang et al.   Journal of Diabetes Research

Selenium Supplementation for Prevention of Colorectal Adenomas and Risk of Associated Type 2 Diabetes

(2016) Patricia A. Thompson et al.   JNCI-Journal of the National Cancer Institute

Regulation of Selenium Metabolism and Transport

(2015) Raymond F. Burk et al.   Annual Review of Nutrition

Diet-Induced Obesity in the Selenocysteine Lyase Knockout Mouse

(2015) Lucia A. Seale et al.   ANTIOXIDANTS & REDOX SIGNALING

Expression of Selenoprotein Genes Is Affected by Obesity of Pigs Fed a High-Fat Diet

(2015) Hua Zhao et al.   JOURNAL OF NUTRITION

The association between dietary selenium intake and diabetes: a cross-sectional study among middle-aged and older adults

(2015) Jie Wei et al.   Nutrition Journal

Biomarkers of Selenium Status

(2015) Gerald F. Combs et al.   Nutrients

Tissue-Specific Inactivation of Type 2 Deiodinase Reveals Multilevel Control of Fatty Acid Oxidation by Thyroid Hormone in the Mouse

(2014) Tatiana L. Fonseca et al.   DIABETES

Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes

(2014) Nathalie Esser et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Selenoproteins: Molecular Pathways and Physiological Roles

(2014) Vyacheslav M. Labunskyy et al.   PHYSIOLOGICAL REVIEWS

High-Fat-Fed Obese Glutathione Peroxidase 1-Deficient Mice Exhibit Defective Insulin Secretion but Protection from Hepatic Steatosis and Liver Damage

(2013) Troy L. Merry et al.   ANTIOXIDANTS & REDOX SIGNALING

Glutathione Peroxidase Mimic Ebselen Improves Glucose-Stimulated Insulin Secretion in Murine Islets

(2013) Xinhui Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Identification and Determination of Selenoneine, 2-Selenyl-N α , N α , N α -Trimethyl-l-Histidine, as the Major Organic Selenium in Blood Cells in a Fish-Eating Population on Remote Japanese Islands

(2013) Michiaki Yamashita et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Ebselen Treatment Prevents Islet Apoptosis, Maintains Intranuclear Pdx-1 and MafA Levels, and Preserves  -Cell Mass and Function in ZDF Rats

(2013) J. Mahadevan et al.   DIABETES

The PACAP-Regulated Gene Selenoprotein T Is Abundantly Expressed in Mouse and Human β-Cells and Its Targeted Inactivation Impairs Glucose Tolerance

(2013) Gaëtan Prevost et al.   ENDOCRINOLOGY

Genetic variants in selenoprotein P plasma 1 gene (SEPP1) are associated with fasting insulin and first phase insulin response in Hispanics

(2013) Jacklyn N. Hellwege et al.   GENE

Diet-induced obesity mediated by the JNK/DIO2 signal transduction pathway

(2013) S. Vernia et al.   GENES & DEVELOPMENT

Deletion of Selenoprotein M Leads to Obesity without Cognitive Deficits

(2013) Matthew W. Pitts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coordination of hypothalamic and pituitary T3 production regulates TSH expression

(2013) Tatiana L. Fonseca et al.   JOURNAL OF CLINICAL INVESTIGATION

Selenium and the thyroid

(2013) Josef Köhrle   Current Opinion in Endocrinology Diabetes and Obesity

Selenium Toxicity from a Misformulated Dietary Supplement, Adverse Health Effects, and the Temporal Response in the Nail Biologic Monitor

(2013) John Morris et al.   Nutrients

Efficient Hepatic Delivery of Drugs: Novel Strategies and Their Significance

(2013) Nidhi Mishra et al.   Biomed Research International

Selenium Downregulates RAGE and NFκB Expression in Diabetic Rats

(2012) Sneha S. Pillai et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Supranutritional selenium induces alterations in molecular targets related to energy metabolism in skeletal muscle and visceral adipose tissue of pigs

(2012) Antonio Pinto et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Prolonged Dietary Selenium Deficiency or Excess Does Not Globally Affect Selenoprotein Gene Expression and/or Protein Production in Various Tissues of Pigs

(2012) Yan Liu et al.   JOURNAL OF NUTRITION

Dietary Selenium Deficiency Partially Rescues Type 2 Diabetes–Like Phenotypes of Glutathione Peroxidase-1–Overexpressing Male Mice

(2012) Xi Yan et al.   JOURNAL OF NUTRITION

Selenium and human health

(2012) Margaret P Rayman   LANCET

Disruption of the Selenocysteine Lyase-Mediated Selenium Recycling Pathway Leads to Metabolic Syndrome in Mice

(2012) L. A. Seale et al.   MOLECULAR AND CELLULAR BIOLOGY

Composition and Evolution of the Vertebrate and Mammalian Selenoproteomes

(2012) Marco Mariotti et al.   PLoS One

Selenium Regulation of the Selenoprotein and Nonselenoprotein Transcriptomes in Rodents

(2012) Roger A. Sunde et al.   Advances in Nutrition

Both Maximal Expression of Selenoproteins and Selenoprotein Deficiency Can Promote Development of Type 2 Diabetes-Like Phenotype in Mice

(2011) Vyacheslav M. Labunskyy et al.   ANTIOXIDANTS & REDOX SIGNALING

The Thyroid Hormone-Inactivating Type III Deiodinase Is Expressed in Mouse and Human β-Cells and Its Targeted Inactivation Impairs Insulin Secretion

(2011) Mayrin C. Medina et al.   ENDOCRINOLOGY

Adaptive dysfunction of selenoproteins from the perspective of the triage theory: why modest selenium deficiency may increase risk of diseases of aging

(2011) Joyce C. McCann et al.   FASEB JOURNAL

Serum Selenoprotein P Levels in Patients with Type 2 Diabetes and Prediabetes: Implications for Insulin Resistance, Inflammation, and Atherosclerosis

(2011) S. J. Yang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Selenium, selenoproteins and the thyroid gland: interactions in health and disease

(2011) Lutz Schomburg   Nature Reviews Endocrinology

Determinants of selenium status in healthy adults

(2011) Gerald F Combs et al.   Nutrition Journal

Mice with a Targeted Deletion of the Type 2 Deiodinase Are Insulin Resistant and Susceptible to Diet Induced Obesity

(2011) Alessandro Marsili et al.   PLoS One

Establishing optimal selenium status: results of a randomized, double-blind, placebo-controlled trial

(2010) Rachel Hurst et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Impacts of Dietary Selenium Deficiency on Metabolic Phenotypes of Diet-Restricted GPX1-Overexpressing Mice

(2010) Matthew P. Pepper et al.   ANTIOXIDANTS & REDOX SIGNALING

Knockouts of SOD1 and GPX1 Exert Different Impacts on Murine Islet Function and Pancreatic Integrity

(2010) Xiaodan Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Serum selenium and serum lipids in US adults: National Health and Nutrition Examination Survey (NHANES) 2003–2004

(2010) Martin Laclaustra et al.   ATHEROSCLEROSIS

A prospective study of dietary selenium intake and risk of type 2 diabetes

(2010) Saverio Stranges et al.   BMC PUBLIC HEALTH

A Liver-Derived Secretory Protein, Selenoprotein P, Causes Insulin Resistance

(2010) Hirofumi Misu et al.   Cell Metabolism

Identification of a Novel Selenium-containing Compound, Selenoneine, as the Predominant Chemical Form of Organic Selenium in the Blood of Bluefin Tuna

(2010) Yumiko Yamashita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathogenesis of Insulin Resistance in Skeletal Muscle

(2010) Muhammad A. Abdul-Ghani et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Mutations in the selenocysteine insertion sequence–binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans

(2010) Erik Schoenmakers et al.   JOURNAL OF CLINICAL INVESTIGATION

Plasma selenium and risk of dysglycemia in an elderly French population: results from the prospective Epidemiology of Vascular Ageing Study

(2010) Tasnime N Akbaraly et al.   Nutrition & Metabolism

Serum selenium concentration is associated with metabolic factors in the elderly: a cross-sectional study

(2010) Kuen-Cheh Yang et al.   Nutrition & Metabolism

Plasma selenoproteins concentrations in type 2 diabetes mellitus—a pilot study

(2010) Marco Roman et al.   Translational Research

Site-Specific Antiatherogenic Effect of the Antioxidant Ebselen in the Diabetic Apolipoprotein E–Deficient Mouse

(2009) Phyllis Chew et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Reactive Oxygen Species Enhance Insulin Sensitivity

(2009) Kim Loh et al.   Cell Metabolism

Endoplasmic Reticulum Stress Plays a Central Role in Development of Leptin Resistance

(2009) Lale Ozcan et al.   Cell Metabolism

β-Cell-Specific Overexpression of Glutathione Peroxidase Preserves Intranuclear MafA and Reverses Diabetes indb/dbMice

(2009) Jamie S. Harmon et al.   ENDOCRINOLOGY

Serum Selenium Concentrations and Diabetes in U.S. Adults: National Health and Nutrition Examination Survey (NHANES) 2003–2004

(2009) Martin Laclaustra et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Molecular mechanisms for hyperinsulinaemia induced by overproduction of selenium-dependent glutathione peroxidase-1 in mice

(2008) X. D. Wang et al.   DIABETOLOGIA

Effect of Selenium and Vitamin E on Risk of Prostate Cancer and Other Cancers

(2008) Scott M. Lippman et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effect of selenium on pancreatic proinflammatory cytokines in streptozotocin-induced diabetic mice

(2008) Jinhong Zeng et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Selenium as an anticancer nutrient: roles in cell proliferation and tumor cell invasion

(2007) Huawei Zeng et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY