3D genome alterations in T cells associated with disease activity of systemic lupus erythematosus

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SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression

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Expression profile of PU.1 in CD4+T cells from patients with systemic lupus erythematosus

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Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease

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Management strategies and future directions for systemic lupus erythematosus in adults

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Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes

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BCL-6 suppresses miR-142-3p/5p expression in SLE CD4+ T cells by modulating histone methylation and acetylation of the miR-142 promoter

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Sci-Hi-C: A single-cell Hi-C method for mapping 3D genome organization in large number of single cells

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The pathogenesis of systemic lupus erythematosus: Harnessing big data to understand the molecular basis of lupus

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DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus

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A randomized control trial to establish the feasibility and safety of rapamycin treatment in an older human cohort: Immunological, physical performance, and cognitive effects

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Understanding the 3D genome: Emerging impacts on human disease

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Pioneering, chromatin remodeling, and epigenetic constraint in early T-cell gene regulation by SPI1 (PU.1)

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Mapping 3D genome organization relative to nuclear compartments using TSA-Seq as a cytological ruler

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ChIP‐Atlas: a data‐mining suite powered by full integration of public ChIP‐seq data

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Microglia-dependent synapse loss in type I interferon-mediated lupus

(2017) Allison R. Bialas et al.   NATURE

Differential effects on lung and bone metastasis of breast cancer by Wnt signalling inhibitor DKK1

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Epigenetics in SLE

(2017) Christian Michael Hedrich   Current Rheumatology Reports

DDX60L Is an Interferon-Stimulated Gene Product Restricting Hepatitis C Virus Replication in Cell Culture

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Insulator dysfunction and oncogene activation in IDH mutant gliomas

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TH9 cells that express the transcription factor PU.1 drive T cell–mediated colitis via IL-9 receptor signaling in intestinal epithelial cells

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The Hierarchy of the 3D Genome

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Single-cell Hi-C reveals cell-to-cell variability in chromosome structure

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A high-resolution map of the three-dimensional chromatin interactome in human cells

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High-Resolution Mapping of the Spatial Organization of a Bacterial Chromosome

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DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes

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An integrated encyclopedia of DNA elements in the human genome

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Topological domains in mammalian genomes identified by analysis of chromatin interactions

(2012) Jesse R. Dixon et al.   NATURE

Systematic Localization of Common Disease-Associated Variation in Regulatory DNA

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Discovery of Atg5/Atg7-independent alternative macroautophagy

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Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

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