Low-intensity focused ultrasound attenuates early traumatic brain injury by OX-A/NF-κB/NLRP3 signaling pathway

Low-intensity focused ultrasound stimulation reverses social avoidance behavior in mice experiencing social defeat stress

(2022) Yimeng Wang et al.   CEREBRAL CORTEX

Low-Intensity Focused Ultrasound Stimulation Ameliorates Working Memory Dysfunctions in Vascular Dementia Rats via Improving Neuronal Environment

(2022) Faqi Wang et al.   Frontiers in Aging Neuroscience

Orexin-A Attenuates Inflammatory Responses in Lipopolysaccharide-Induced Neural Stem Cells by Regulating NF-KB and Phosphorylation of MAPK/P38/Erk Pathways

(2021) Wen Ye et al.   Journal of Inflammation Research

Wakefulness-Promoting Effects of Lateral Hypothalamic Area–Deep Brain Stimulation in Traumatic Brain Injury-Induced Comatose Rats: Upregulation of α1-Adrenoceptor Subtypes and Downregulation of Gamma-Aminobutyric Acid β Receptor Expression Via the Orexins Pathway

(2021) Xiaoyang Dong et al.   World Neurosurgery

Microenvironmental Variations After Blood-Brain Barrier Breakdown in Traumatic Brain Injury

(2021) Yue Hu et al.   Frontiers in Molecular Neuroscience

Orexin A alleviates neuroinflammation via OXR2/CaMKKβ/AMPK signaling pathway after ICH in mice

(2020) Tao Li et al.   Journal of Neuroinflammation

Ultrasonic Neuromodulation and Sonogenetics: A New Era for Neural Modulation

(2020) Songyun Wang et al.   Frontiers in Physiology

Serotonergic neurons in the dorsal raphe nucleus mediate the arousal-promoting effect of orexin during isoflurane anesthesia in male rats

(2019) Cen Yang et al.   NEUROPEPTIDES

The protective effects of orexin a against high glucose-induced activation of NLRP3 inflammasome in human vascular endothelial cells

(2019) Chengxi Zhang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

RAGE/NF-κB pathway mediates hypoxia-induced insulin resistance in 3T3-L1 adipocytes

(2019) Yunliang Tang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The p53 inactivators pifithrin-μ and pifithrin-α mitigate TBI-induced neuronal damage through regulation of oxidative stress, neuroinflammation, autophagy and mitophagy

(2019) Ling-Yu Yang et al.   EXPERIMENTAL NEUROLOGY

Ultrasound Elicits Behavioral Responses through Mechanical Effects on Neurons and Ion Channels in a Simple Nervous System

(2018) Jan Kubanek et al.   JOURNAL OF NEUROSCIENCE

Dimethyl Fumarate Attenuates Neuroinflammation and Neurobehavioral Deficits Induced by Experimental Traumatic Brain Injury

(2018) Giovanna Casili et al.   JOURNAL OF NEUROTRAUMA

Selective NLRP3 inflammasome inhibitor reduces neuroinflammation and improves long-term neurological outcomes in a murine model of traumatic brain injury

(2018) Xin Xu et al.   NEUROBIOLOGY OF DISEASE

Orexin A Suppresses Oxidized LDL Induced Endothelial Cell Inflammation via MAPK p38 and NF-κB Signaling Pathway

(2018) Haiyang Zhang et al.   IUBMB LIFE

Investigation of New Orexin 2 Receptor Modulators Using In Silico and In Vitro Methods

(2018) Jana Janockova et al.   MOLECULES

Orexin-A Exerts Neuroprotective Effects via OX1R in Parkinson’s Disease

(2018) Mei-Fang Liu et al.   Frontiers in Neuroscience

Isoliquiritigenin alleviates early brain injury after experimental intracerebral hemorrhage via suppressing ROS- and/or NF-κB-mediated NLRP3 inflammasome activation by promoting Nrf2 antioxidant pathway

(2017) Jun Zeng et al.   Journal of Neuroinflammation

Pathophysiology of Traumatic Brain Injury

(2017) Kirsty J. Dixon   Physical Medicine and Rehabilitation Clinics of North America

Low-intensity pulsed ultrasound improves behavioral and histological outcomes after experimental traumatic brain injury

(2017) Wei-Shen Su et al.   Scientific Reports

Rapid eye movement sleep disruption and sleep fragmentation are associated with increased orexin-A cerebrospinal-fluid levels in mild cognitive impairment due to Alzheimer's disease

(2016) Claudio Liguori et al.   NEUROBIOLOGY OF AGING

NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases

(2015) Amna Abderrazak et al.   Redox Biology

Orexin receptors exert a neuroprotective effect in Alzheimer’s disease (AD) via heterodimerization with GPR103

(2015) Julie Davies et al.   Scientific Reports

Neuroprotection by Orexin-A via HIF-1α induction in a cellular model of Parkinson's disease

(2014) Ya Feng et al.   NEUROSCIENCE LETTERS

Changing patterns in the epidemiology of traumatic brain injury

(2013) Bob Roozenbeek et al.   Nature Reviews Neurology

Pentylenetetrazol-induced seizures are exacerbated by sleep deprivation through orexin receptor-mediated hippocampal cell proliferation

(2013) Li Yan Ni et al.   NEUROLOGICAL SCIENCES

Mitigation of Murine Focal Cerebral Ischemia by the Hypocretin/Orexin System is Associated With Reduced Inflammation

(2013) Xiaoxing Xiong et al.   STROKE

Role of orexin in modulating arousal, feeding, and motivation

(2013) Natsuko Tsujino et al.   Frontiers in Behavioral Neuroscience

Transcranial Focused Ultrasound to the Thalamus Is Associated with Reduced Extracellular GABA Levels in Rats

(2012) Po Song Yang et al.   NEUROPSYCHOBIOLOGY

A review of low-intensity focused ultrasound pulsation

(2011) Alexander Bystritsky et al.   Brain Stimulation

Intramembrane cavitation as a unifying mechanism for ultrasound-induced bioeffects

(2011) B. Krasovitski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression and Localization of the Orexin-1 Receptor (OX1R) After Traumatic Brain Injury in Mice

(2010) Yuko Mihara et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The effect of orexin-A on the pathological mechanism in the rat focal cerebral ischemia

(2010) Eiji Kitamura et al.   NEUROSCIENCE RESEARCH

Neutralization of interleukin-1β modifies the inflammatory response and improves histological and cognitive outcome following traumatic brain injury in mice

(2009) Fredrik Clausen et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

CSF orexin-A/hypocretin-1 concentrations in patients with intracerebral hemorrhage (ICH)

(2007) Kenji Dohi et al.   REGULATORY PEPTIDES