Universal and Sensitive Drug Assessment Biosensing Platform Using Optimal Mechanical Beating Detection of Single Cardiomyocyte

Microengineered platforms for characterizing the contractile function of in vitro cardiac models

(2022) Wenkun Dou et al.   Microsystems & Nanoengineering

Cardiotoxicity assessment using 3D vascularized cardiac tissue consisting of human iPSC-derived cardiomyocytes and fibroblasts

(2021) Kiyoshi Tadano et al.   Molecular Therapy-Methods & Clinical Development

Highly durable crack sensor integrated with silicone rubber cantilever for measuring cardiac contractility

(2020) Dong-Su Kim et al.   Nature Communications

Specific recognition of ion channel blocker by high-content cardiomyocyte electromechanical integrated correlation

(2020) Hongbo Li et al.   BIOSENSORS & BIOELECTRONICS

Dynamic Model for Characterizing Contractile Behaviors and Mechanical Properties of a Cardiomyocyte

(2018) Chuang Zhang et al.   BIOPHYSICAL JOURNAL

Synchronized electromechanical integration recording of cardiomyocytes

(2018) Ning Hu et al.   BIOSENSORS & BIOELECTRONICS

Definition of hidden drug cardiotoxicity: paradigm change in cardiac safety testing and its clinical implications

(2018) Péter Ferdinandy et al.   EUROPEAN HEART JOURNAL

Spiral-shaped SU-8 cantilevers for monitoring mechanical response of cardiomyocytes treated with cardiac drugs

(2018) Y. Dai et al.   SENSORS AND ACTUATORS B-CHEMICAL

Decreased contractility and altered responses to inotropic agents in myocytes from tachypacing-induced heart failure canines

(2018) BaoXi Gao et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

European Society of Cardiology: Cardiovascular Disease Statistics 2017

(2017) et al.   EUROPEAN HEART JOURNAL

Piezoresistive sensor-integrated PDMS cantilever: A new class of device for measuring the drug-induced changes in the mechanical activity of cardiomyocytes

(2017) Dong-Su Kim et al.   SENSORS AND ACTUATORS B-CHEMICAL

Evaluation of drug-mediated arrhythmic changes in spontaneous beating cardiomyocytes by AFM

(2016) A. T. Chen et al.   ANALYST

Surface-patterned SU-8 cantilever arrays for preliminary screening of cardiac toxicity

(2016) Jong Yun Kim et al.   BIOSENSORS & BIOELECTRONICS

Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015

(2016) Haidong Wang et al.   LANCET

Micropost arrays for measuring stem cell-derived cardiomyocyte contractility

(2016) Kevin M. Beussman et al.   METHODS

High-performance beating pattern function of human induced pluripotent stem cell-derived cardiomyocyte-based biosensors for hERG inhibition recognition

(2015) Ning Hu et al.   BIOSENSORS & BIOELECTRONICS

Multimodal SHG-2PF Imaging of Microdomain Ca 2+ -Contraction Coupling in Live Cardiac MyocytesNovelty and Significance

(2015) Samir Awasthi et al.   CIRCULATION RESEARCH

Enhanced Characterization of Contractility in Cardiomyocytes During Early Drug Safety Assessment

(2015) Larissa Butler et al.   TOXICOLOGICAL SCIENCES

Matrix elasticity regulates the optimal cardiac myocyte shape for contractility

(2014) Megan L. McCain et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Measuring the Contractile Forces of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes With Arrays of Microposts

(2014) Marita L. Rodriguez et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

A cardiomyocyte-based biosensor for antiarrhythmic drug evaluation by simultaneously monitoring cell growth and beating

(2013) Tianxing Wang et al.   BIOSENSORS & BIOELECTRONICS

Drug attrition during pre-clinical and clinical development: Understanding and managing drug-induced cardiotoxicity

(2013) Nicola Ferri et al.   PHARMACOLOGY & THERAPEUTICS

The pathophysiology of heart failure

(2012) Clinton D. Kemp et al.   CARDIOVASCULAR PATHOLOGY

Optical Imaging of Voltage and Calcium in Cardiac Cells & Tissues

(2012) Todd J. Herron et al.   CIRCULATION RESEARCH