Article
Engineering, Geological
Wan-li Guo, Dan-qing Song, Xiao-mei Li
Summary: The impact of particle breakage on the critical state line (CSL) of granular soils has been investigated in this study. Large-scale shearing tests were conducted on rockfill materials under different initial gradations, void ratios, and confining pressures. The results showed that particle breakage leads to decreases in both stress ratio and void ratio at the critical state. A unified equation for CSL and a none breakage critical state line (NBCSL) was derived, where the intercept and gradient are related to particle breakage. This study provides insights into the translation and rotation of CSL induced by changing gradation and void ratio from the perspective of particle breakage.
Article
Engineering, Chemical
D. D. Shi, D. Cao, Y. B. Deng, J. F. Xue
Summary: The effects of intermediate principal stress ratio and particle breakage on the critical state behaviors of granular materials were studied in DEM analyses. It was found that these factors influence the dilation and peak strength of granular materials, but have different effects on the critical stress ratios of the assemblies.
Article
Engineering, Geological
ErLu Wu, Jungao Zhu, Huifeng Zheng, Wanli Guo, Xiaolong Zhao, Mengdie Bao
Summary: In traditional plasticity mechanics, the plastic flow direction and loading direction in soil modeling are different, which requires separate establishment of the plastic potential surface and yield surface. However, this difference can be described by introducing the fractional calculus. In this study, a new modeling approach using the fractional derivative of Riemann-Liouville is adopted, which accurately captures the stress-strain behaviors of rockfill materials.
Article
Engineering, Environmental
Hamidreza Rahmani, Ali Komak Panah
Summary: Research has shown that changing the maximum particle size of weak rockfill affects particle breakage. Increasing moisture content leads to increased particle breakage. The internal friction angle is directly related to the maximum particle size, while the ratio of vertical strain to particle breakage remains nearly constant.
BULLETIN OF ENGINEERING GEOLOGY AND THE ENVIRONMENT
(2021)
Article
Engineering, Geological
Wan-li Guo, Ge Chen
Summary: This paper investigates particle breakage in rockfill during shearing. By using a reduction strategy for the friction coefficient, a method to estimate the breakage energy is developed. The results show that the particle breakage indices and fractal dimension are proportional to the breakage energy.
Article
Engineering, Geological
Chuanfeng Fang, Jian Gong, Mingtao Jia, Zhihong Nie, Wei Hu, Bo Li
Summary: This study investigated the effect of intermediate principal stress on the mechanical behavior of breakable granular materials using a DEM simulation. The results showed that increasing the intermediate principal stress initially increased and then decreased the peak shear strength, while also increasing particle breakage and the number of cracks.
Article
Engineering, Environmental
Long Wang, Jungao Zhu, Zongliang Zhang, Huifeng Zheng
Summary: Dry density has significant effects on the stress-strain characteristics, peak friction angle, and secant modulus of slate rockfill materials. A non-linear shear strength envelope is proposed to describe shear resistance, with dry density influencing peak friction angle while confining pressure affects it inversely. Moreover, dry density also plays a role in particle breakage for the slate material.
BULLETIN OF ENGINEERING GEOLOGY AND THE ENVIRONMENT
(2021)
Article
Multidisciplinary Sciences
Qinglin Chen, Zugui Li, Zeyu Dai, Xiaojun Wang, Chao Zhang, Xuepeng Zhang
Summary: This study examines the impact of stress levels on the mechanical properties and particle crushing behavior of irregular granular materials. Discrete element method is used to model granular materials with irregular sides. A new method is proposed to characterize the deformation of irregular granular materials under high pressure using a shear fracture zone. The energy analysis of particle crushing is based on the first law of thermodynamics. The shear strength of irregular granular materials exhibits significant nonlinear behavior due to particle crushing. The deformation behavior is characterized by particle rotation under low confining pressure, and by particle breakage under high confining pressure. Granular materials easily break into numerous fine particles under high confining pressure, with the degree of breakage represented by the value of crushing energy. Irregular granular materials have a high degree of breakage under high confining pressures, leading to reduced stability in engineered structures constructed from such materials.
SCIENTIFIC REPORTS
(2023)
Article
Engineering, Geological
Chaomin Shen, Sihong Liu, Liujiang Wang
Summary: An elasto-plastic constitutive model for rockfill materials considering particle breakage is proposed in this study, where parameters are derived based on the evolution of microstructures formed by rockfill particles, allowing for a reasonable description of the static loading characteristics of rockfill materials.
Article
Engineering, Geological
Chen-Xi Tong, Ming-Yue Zhai, Hai-Chao Li, Sheng Zhang, Daichao Sheng
Summary: This paper summarizes the latest advances in studying the effects of soil particle breakage on soil mechanics properties and relevant constitutive models. By quantifying particle size distribution and the evolution of particle breakage, a new critical state model treating PSD as a variable is proposed. The model is validated against experimental data and compared with other constitutive models, showing satisfactory performance.
Article
Engineering, Environmental
Xing Wang, Xinzhi Wang, Jianhua Shen, Changqi Zhu
Summary: This study investigates the influence of particle size and confining pressure on the shear characteristics of coral sand. The results show that an increase in effective confining pressure weakens the strain-softening and dilatancy of the coral sand. Particle size affects the internal friction angle and apparent cohesion of the coral sand. Coarse coral sand exhibits the highest degree of particle breakage.
BULLETIN OF ENGINEERING GEOLOGY AND THE ENVIRONMENT
(2022)
Article
Engineering, Geological
Yu-ran Xu, Yongfu Xu
Summary: The study utilized discrete element software for numerical simulation of rock single particle crushing and rockfill direct shear test, revealing a power function relationship between shear strength and normal stress, with the exponent dependent on the particle fractal dimension.
Article
Engineering, Environmental
Shuang Jiao, Chengshun Xu, Shuang Xu, Jialin Xu
Summary: The discrete element method (DEM) can be used to study the breakage of granular materials from a microscopic perspective. Through numerical simulations, the influencing factors and microscopic responses of breakage are investigated, as well as the critical state of crushed specimens. The results show that the shearing dilatancy characteristics are governed by the stress level and that the content of fine particles affects the amount of breakage. Particle breakage mainly occurs at the early stage of shear at low confining pressure, while it accompanies the whole shear process at high confining pressure.
BULLETIN OF ENGINEERING GEOLOGY AND THE ENVIRONMENT
(2023)
Article
Construction & Building Technology
Haoyue Fan, Zhenghong Tian, Xiaobin Xu, Xiao Sun, Yuanshan Ma, Hengrui Liu, Hao Lu
Summary: This paper proposes a gradation detection method based on deep learning, which can output detection results end-to-end. The method utilizes a modified MASK R-CNN model to locate and segment rockfill materials. The results show that the proposed method has high accuracy and can quickly obtain the gradation of rockfill materials.
CASE STUDIES IN CONSTRUCTION MATERIALS
(2022)
Article
Mathematics, Interdisciplinary Applications
Mahmood Ahmad, Ramez A. Al-Mansob, Kazem Reza Kashyzadeh, Suraparb Keawsawasvong, Mohanad Muayad Sabri Sabri, Irfan Jamil, Arnold C. Alguno
Summary: This study investigates the feasibility of using XGBoost computing paradigm to estimate the shear strength of rockfill materials, demonstrating that the XGBoost model outperforms other models in terms of performance evaluation metrics and is a reliable predictive model.
Article
Biochemistry & Molecular Biology
Yalan Li, Shengsheng Li, Liyuan Wu, Tingting Wu, Mengxiao Li, Deliang Du, Yalin Chen, Caiji Wang, Xuanyi Li, Shili Zhang, Zeqi Zhao, Liting Zheng, Mengbing Chen, Menghua Li, Ting Li, Xi Shi, Yuehua Qiao
Summary: This study revealed that SESN2 acts as a protective factor against noise-induced hearing loss (NIHL) by activating Parkin-mediated mitophagy and alleviating oxidative stress. Deficiency of SESN2 blocks mitophagy and exacerbates acoustic trauma. These findings suggest that SESN2 may be a potential therapeutic target for noise-induced cochlear injury.
ANTIOXIDANTS & REDOX SIGNALING
(2023)
Article
Clinical Neurology
Yunju Yang, Maria J. Knol, Ruiqi Wang, Aniket Mishra, Dan Liu, Michelle Luciano, Alexander Teumer, Nicola Armstrong, Joshua C. Bis, Min A. Jhun, Shuo Li, Hieab H. H. Adams, Nasir Ahmad Aziz, Mark E. Bastin, Mathieu Bourgey, Jennifer A. Smith, Stefan Frenzel, Rebecca F. Gottesman, Norbert Hosten, Lifang Hou, Sharon L. R. Kardia, Valerie Lohner, Pascale Marquis, Susana Munoz Maniega, Claudia L. Satizabal, Farzaneh A. Sorond, Maria C. Valdes Hernandez, Cornelia M. van Duijn, Meike W. Vernooij, Katharina Wittfeld, Qiong Yang, Wei Zhao, Eric Boerwinkle, Daniel Levy, Ian J. Deary, Jiyang Jiang, Karen A. Mather, Thomas H. Mosley, Bruce M. Psaty, Perminder S. Sachdev, Jennifer A. Smith, Nona Sotoodehnia, Charles S. DeCarli, Monique M. B. Breteler, M. Arfan Ikram, Hans J. Grabe, Joanna Wardlaw, W. T. Longstreth, Lenore J. Launer, Sudha Seshadri, Stephanie Debette, Myriam Fornage
Summary: This study investigates the association between epigenetic changes and white matter hyperintensities in adults. The findings suggest that blood-brain barrier dysfunction and the immune response are related to white matter hyperintensity burden, and antihyperlipidemic agents might be a potential treatment.
Article
Oncology
Zhaoping Zang, Yi Shao, Rena Nakyeyune, Yi Shen, Chen Niu, Lingyan Zhu, Xiaoli Ruan, Tong Wei, Ping Wei, Fen Liu
Summary: This study used the Mendelian randomization (MR) method to investigate the causal relationship between body mass index (BMI) and the risk of gastro-esophageal cancer. The results showed no evidence of a causal association between BMI and gastric or esophageal cancer. Sensitivity analysis and gender-stratified analysis also did not reveal any causal relationship evidence.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
(2023)
Article
Chemistry, Medicinal
Xiaobao Gong, Zhenwei Gui, Xiaoli Ye, Xuegang Li
Summary: This study discovered that jatrorrhizine, an active constituent of Rhizoma Coptidis, significantly improved diabetic peripheral neuropathy. The findings showed that jatrorrhizine treatment reduced the sensitivity threshold for thermal and mechanical stimuli and increased nerve conduction velocity. Moreover, jatrorrhizine increased the number of nerve fibers and axons, myelin thickness, and axonal diameters. The study also revealed that jatrorrhizine enhanced Schwann cells' myelination by regulating the NRG1-ErbB2-PI3K-AKT pathway.
PHYTOTHERAPY RESEARCH
(2023)
Article
Plant Sciences
Xiaxiang Zhang, Rui Xing, Yunjia Ding, Jingjin Yu, Ruying Wang, Xiaohui Li, Zhimin Yang, Lili Zhuang
Summary: This study identified FaGA2ox4 as a gene with the highest expression level in tall fescue under drought stress. Transgenic rice plants overexpressing FaGA2ox4 exhibited a dwarf and high-tillering phenotype, and also showed improved drought stress tolerance.
ENVIRONMENTAL AND EXPERIMENTAL BOTANY
(2023)
Article
Engineering, Environmental
Ruijuan Liu, Xinni Wu, Wanhui Zhang, Yuheng Chen, Jianwei Fu, Huase Ou
Summary: Disinfection in water treatments induces microplastics to produce various volatile organic compounds (VOCs), and the production of these VOCs is influenced by the polymer types of microplastics and different disinfection mechanisms.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Chemistry, Organic
Mingqin Zhao, Jingyi Hu, Xiaoming Ji, Lu Han, Mengxiao Li, Miao Lai
Summary: A transition-metal and ligand free base-mediated radical condensation reaction to form N-substituted pyrrolyl ketones with water as a side product has been developed. The reaction tolerates a wide range of N-substituted acetylpyrroles and alcohols. The key intermediate is proposed to be the radical anion of the benzylic alcohol, which undergoes coupling with the enolate of the acetylpyrrole to form the new C-C bond. The corresponding pyrrolyl chalcones are obtained by elimination, and the enone intermediate is reduced to afford N-substituted pyrrolyl ketones.
JOURNAL OF HETEROCYCLIC CHEMISTRY
(2023)
Article
Reproductive Biology
Bei-Bei Zhang, Meng-Xiao Li, Hong-Na Wang, Chao Liu, Yan-Yan Sun, Teng-He Ma
Summary: In this study, the expression of lncRNAs and mRNAs associated with ovarian follicle development in Taihang chickens was analyzed at the genome-wide level. The findings identified key pathways and regulatory factors related to follicle selection, providing a new foundation for future research on reproductive physiology in Taihang chickens and offering new opportunities to improve their laying performance.
Article
Oncology
Shuwen Han, Yangyanqiu Wang, Jian Chu, Boyang Hu, Gong Gong, Jing Zhuang
Summary: This study found that sodium butyrate (NaB) is a metabolite that affects the efficacy of oxaliplatin (OXA). NaB and OXA can synergistically inhibit the proliferation, migration, and invasion of colorectal cancer cells and promote cell apoptosis. This suggests that NaB has the potential to become a new clinical adjuvant in colorectal cancer chemotherapy.
TRANSLATIONAL ONCOLOGY
(2023)
Editorial Material
Pediatrics
Lin Yang, Lina Chen, Liang Xie, Ying Xiong, Hanmin Liu
PEDIATRIC PULMONOLOGY
(2023)
Article
Engineering, Geological
Yang Xiao, Hanghang Zhao, Huanran Wu, Xiang Jiang, Hanlong Liu
Summary: In this study, Brazilian splitting tests were conducted on intact sandstone specimens to investigate the anisotropic strength of rock with biotreated cracks. The results showed that the apparent tensile strength of the biotreated specimens can reach and even exceed that of the intact specimens, with low anisotropy. This finding indicates that biotreatment is a remarkable method for repairing cracks in stone-cultural relics.
INTERNATIONAL JOURNAL OF GEOMECHANICS
(2023)
Article
Engineering, Geological
Yang Xiao, Qingyun Fang, Armin W. Stuedlein, T. Matthew Evans
Summary: A series of drained triaxial tests were conducted on sandy soils with different mean particle sizes to investigate the effect of particle size and shape on soil strength and dilatancy. The results showed that the maximum and critical-state friction angles of rounded glass bead sands increased slightly with increasing particle size, while the critical-state friction angle of angular crushed glass sands decreased. The maximum dilation angle of both angular crushed glass and rounded glass bead sands increased with larger particle size. The comparison of different sands demonstrated that the strength and friction angle of granular soils are directly influenced by particle angularity and interparticle locking.
INTERNATIONAL JOURNAL OF GEOMECHANICS
(2023)
Article
Clinical Neurology
Yinglun Tian, Nanfang Xu, Ming Yan, Jinguo Chen, Kan-Lin Hung, Xiangyu Hou, Shenglin Wang, Weishi Li
Summary: The study aims to clarify the anatomical relationship between the internal carotid artery (ICA) and the bony structures of the craniovertebral junction in sandwich atlantoaxial dislocation (AAD) patients, and analyze the risks of injury during surgical procedures. The results indicate the importance of paying attention to the position of the ICA during surgery to prevent injury. This study is crucial for surgical safety and prevention of potential risks.
ACTA NEUROCHIRURGICA
(2023)
Review
Chemistry, Physical
Xiaohui Li, Xiaodong Li, Quanhu Sun, Jianjiang He, Ze Yang, Jinchong Xiao, Changshui Huang
Summary: Graphdiyne (GDY) is a two-dimensional material with various morphologies and structures, exhibiting excellent electronic, chemical, magnetic, and mechanical properties, making it suitable for applications in energy storage, catalysis, and field emission. By replacing hexaethylbenzene, different GDY derivatives with specific structures and controllable sizes can be synthesized.
ACTA PHYSICO-CHIMICA SINICA
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Qiurong Wei, Zeli Chen, Yehuan Tang, Weicui Chen, Liming Zhong, Liting Mao, Shaowei Hu, Yuankui Wu, Kan Deng, Wei Yang, Xian Liu
Summary: This study developed a machine learning model to predict the pathological complete response (pCR) in rectal cancer patients after neoadjuvant chemoradiotherapy, and compared the performance of different classifiers. The results showed that the random forest algorithm performed well in predicting pCR.
EUROPEAN RADIOLOGY
(2023)
