Diabetes induced by gain-of-function mutations in the Kir6.1 subunit of the K ATP channel

Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes

(2016) Åsa Segerstolpe et al.   Cell Metabolism

Remission of Severe Neonatal Diabetes With Very Early Sulfonylurea Treatment

(2015) Bess A. Marshall et al.   DIABETES CARE

Generation of Functional Human Pancreatic β Cells In Vitro

(2014) Felicia W. Pagliuca et al.   CELL

Pancreatic β Cell Dedifferentiation in Diabetes and Redifferentiation following Insulin Therapy

(2014) Zhiyu Wang et al.   Cell Metabolism

Hypotension Due to Kir6.1 Gain‐of‐Function in Vascular Smooth Muscle

(2013) Anlong Li et al.   Journal of the American Heart Association

Acute Sulfonylurea Therapy at Disease Onset Can Cause Permanent Remission of KATP-Induced Diabetes

(2011) M. S. Remedi et al.   DIABETES

Defects in beta cell Ca2+ signalling, glucose metabolism and insulin secretion in a murine model of KATP channel-induced neonatal diabetes mellitus

(2011) R. K. P. Benninger et al.   DIABETOLOGIA

Muscle KATP Channels: Recent Insights to Energy Sensing and Myoprotection

(2010) Thomas P. Flagg et al.   PHYSIOLOGICAL REVIEWS

Secondary Consequences of β Cell Inexcitability: Identification and Prevention in a Murine Model of KATP-Induced Neonatal Diabetes Mellitus

(2009) Maria Sara Remedi et al.   Cell Metabolism

Kir6.2 Variant E23K Increases ATP-Sensitive K+ Channel Activity and Is Associated With Impaired Insulin Release and Enhanced Insulin Sensitivity in Adults With Normal Glucose Tolerance

(2009) D. T. Villareal et al.   DIABETES

Successful sulfonylurea treatment of an insulin-naïve neonate with diabetes mellitus due to a KCNJ11 mutation

(2009) Jennifer A Wambach et al.   PEDIATRIC DIABETES

Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic β cells recapitulates neonatal diabetes

(2008) Christophe A. Girard et al.   JOURNAL OF CLINICAL INVESTIGATION