Article
Infectious Diseases
Jacob D. Edwards, Seth A. Quinn, Marissa Burchette, William Irish, Nathaniel Poulin, Eric A. Toschlog
Summary: This study compares the rates of intra-abdominal complications and the effects of direct peritoneal resuscitation (DPR) in trauma patients. The results showed that the use of DPR did not lead to different outcomes in trauma patients. Therefore, traditional resuscitative measures for damage control surgery (DCS) may be as effective as DCS with DPR.
SURGICAL INFECTIONS
(2022)
Article
Emergency Medicine
Tony Zitek, Ramsey Ataya, Lian Farino, Salman Mohammed, Glenn Miller
Summary: The study did not find an association between receiving more than 1 L of IV crystalloid and in-hospital mortality or the volume of PRBCs transfused among trauma patients, but receiving more than 1 L of crystalloids was associated with a longer hospital length of stay.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Review
Veterinary Sciences
Kelly Hall, Kenneth Drobatz
Summary: Resuscitation of acutely hemorrhaging small animal patients, such as dogs and cats, should prioritize hemorrhage control and judicious crystalloid administration followed by early consideration for blood component therapy to minimize blood loss, ameliorate coagulopathy, restore oxygen delivery, and correct changes in the glycocalyx.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Emergency Medicine
Andrew Khalifa, Jacob B. Avraham, Kristina Z. Kramer, Francesco Bajani, Chih Yuan Fu, Alexandra Pires-Menard, Matthew Kaminsky, Faran Bokhari
Summary: This study analyzed survival characteristics in trauma patients with torso trauma suffering no recorded vital signs in the emergency department from 2007 to 2015. Only a small percentage of patients were declared dead upon arrival, with even fewer patients eventually discharged home. Factors such as injury severity score, penetrating mechanism, and surgical interventions were associated with improved survival outcomes.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Medicine, General & Internal
Tobias Gauss, Justin E. Richards, Costanza Tortu, Francois-Xavier Ageron, Sophie Hamada, Julie Josse, Francois Husson, Anatole Harrois, Thomas M. Scalea, Valentin Vivant, Eric Meaudre, Jonathan J. Morrison, Samue Galvagno, Pierre Bouzat
Summary: This retrospective study evaluated the association between early norepinephrine administration and mortality in patients with blunt trauma and hemorrhagic shock. The findings suggest that early norepinephrine infusion does not affect 24-hour or in-hospital mortality.
Article
Surgery
Jason B. Brill, Krislynn M. Mueck, Brian Tang, Mariela Sandoval, Madeline E. Cotton, C. Cameron McCoy, Bryan A. Cotton
Summary: LTOWB appears to be a safe product for universal use across all blood groups, with no significant differences in survival rates or major complications among recipient blood groups. However, Group B recipients showed lower systolic pressure and higher lactate levels upon arrival.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2023)
Article
Critical Care Medicine
Daniel Jin Keat Lee, Min Li Kang, Lyndsay Mei Janet Christie, Woan Wui Lim, Dorithy Xiu-Hui Tay, Sanjay Patel, Jerry Tiong Thye Goo
Summary: The study demonstrates that implementing the CHOP protocol for managing exsanguinating patients significantly reduces intervention time, lowers mortality rates, and achieves positive outcomes compared to the traditional standard protocol.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2021)
Article
Surgery
Steven W. Thornton, Harold J. Leraas, Elizabeth Horne, Marcelo Cerullo, Doreen Chang, Emily Greenwald, Suresh Agarwal, Krista L. Haines, Elisabeth T. Tracy
Summary: Most injured children receive trauma care outside of a pediatric trauma center, and differences in physiology, dosing, and injury pattern limit the application of adult trauma principles to pediatrics. A comparison between US trauma center experiences with pediatric and adult trauma resuscitation revealed significantly fewer high-acuity pediatric trauma cases, highlighting the need for education and simulation in pediatric trauma resuscitation to improve outcomes.
JOURNAL OF SURGICAL RESEARCH
(2023)
Article
Critical Care Medicine
Alexis L. Cralley, Ernest E. Moore, Joseph Dubose, Megan L. Brenner, Terry R. Schaid, Margot DeBot, Mitchell Cohen, Christopher Silliman, Charles Fox, Angela Sauaia
Summary: This study compared the outcomes of patients treated with REBOA Zone 3 and REBOA Zone 1 for severe blunt pelvic injuries. The results showed that REBOA Zone 3 had better survival rates and comparable outcomes in other adverse events compared to REBOA Zone 1.
Article
Critical Care Medicine
Alexander Bonde, Trine G. Eskesen, Jacob Steinmetz, Erwin M. Schoof, Lene H. D. Blicher, Lars S. Rasmussen, Martin Sillesen
Summary: DNA-methylation changes occur in the rat lung during hemorrhage and saline resuscitation, particularly in genes related to endothelial and immune response signaling. Proteomic responses include activations in mRNA processing and endothelial Nitric Oxide Synthase (eNOS) metabolism.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2021)
Article
Emergency Medicine
Sarah Cavallaro, Joshua Easter
Summary: As a new field, there has been a recent surge in evidence on managing children in the emergency department. This review focuses on 10 recent articles that provide relevant evidence for emergency medicine physicians in caring for children. The articles highlight high prevalence conditions like fever and trauma, as well as interventions that can improve mortality such as cardiopulmonary resuscitation and massive transfusion.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2023)
Article
Critical Care Medicine
Mineji Hayakawa, Takashi Tagami, Daisuke Kudo, Kota Ono, Makoto Aoki, Akira Endo, Tetsuya Yumoto, Yosuke Matsumura, Shiho Irino, Kazuhiko Sekine, Noritaka Ushio, Takayuki Ogura, Sho Nachi, Yuhei Irie, Katsura Hayakawa, Yusuke Ito, Yuko Okishio, Tomohiro Muronoi, Yoshinori Kosaki, Kaori Ito, Keita Nakatsutsumi, Yutaka Kondo, Taichiro Ueda, Hiroshi Fukuma, Yuichi Saisaka, Naoki Tominaga, Takeo Kurita, Fumihiko Nakayama, Tomotaka Shibata, Shigeki Kushimoto
Summary: This study aimed to investigate whether a restrictive transfusion strategy was non-inferior to a liberal transfusion strategy during the acute post-injury phase. The results showed that there was no statistically significant difference in 28-day survival rates between the restrictive and liberal transfusion strategies, but the restrictive strategy resulted in lower transfusion volume.
JOURNAL OF INTENSIVE CARE
(2023)
Article
Critical Care Medicine
Mitsuaki Kojima, Akira Endo, Atsushi Shiraishi, Tomohisa Shoko, Yasuhiro Otomo, Raul Coimbra
Summary: This study investigated the interaction between plasma-to-RBC ratio and age in trauma patients and found that the association between plasma-to-RBC ratio and in-hospital mortality was clear in non-geriatric patients, but inconclusive in geriatric patients.
JOURNAL OF INTENSIVE CARE
(2022)
Article
Emergency Medicine
Jesse P. Wray, Rachel E. Bridwell, Steven G. Schauer, Stacy A. Shackelford, Vikhyat S. Bebarta, Franklin L. Wright, James Bynum, Brit Long
Summary: Calcium is a crucial element in trauma resuscitation and the coagulation cascade. Hypocalcemia can have negative impacts on hemodynamics and coagulation in trauma patients, necessitating timely intervention. Trauma patients often present with hypocalcemia, especially after severe hemorrhage, and early administration of calcium may be beneficial for improving patient outcomes.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Emergency Medicine
Frank Petruzella, Joshua S. Easter
Summary: Most children are treated at general Emergency Departments (EDs) instead of specialized pediatric EDs, so it is important for emergency medicine physicians to stay updated on developments in pediatric emergency medicine. Ten impactful and relevant studies were selected, covering topics such as status epilepticus, cardiac arrest, asthma, and more.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)