Article
Gastroenterology & Hepatology
Sergei Vosko, Neal Shahidi, Mayenaaz Sidhu, W. Arnout van Hattem, Iddo Bar-Yishay, Scott Schoeman, David J. Tate, Luke F. Hourigan, Rajvinder Singh, Alan Moss, Karen Byth, Eric Y. T. Lee, Nicholas G. Burgess, Michael J. Bourke
Summary: This study found significant differences in optical evaluation performance between flat and nodular large nonpedunculated colorectal polyps. Flat lesions can be presumed benign and managed accordingly, while nodular lesions are more likely to be missed for submucosal invasive cancer.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Surgery
Cecily Stockley, Bradley Evans, Muna Lougheed, Haley Flemming, Altaf Taher, Mark Borgaonkar, David Pace
Summary: The study examined local practices for non-malignant polyps and calculated morbidity and mortality associated with bowel resection for this indication. The results showed that surgery for benign colonic polyps is associated with significant morbidity and mortality, highlighting a gap in the endoscopic management of benign colonic polyps.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Gastroenterology & Hepatology
Timothy O'Sullivan, David Tate, Mayenaaz Sidhu, Sunil Gupta, James Elhindi, Karen Byth, Oliver Cronin, Anthony Whitfield, Ana Craciun, Rajvinder Singh, Gregor Brown, Spiro Raftopoulos, Luke Hourigan, Alan Moss, Amir Klein, Steven Heitman, Stephen Williams, Eric Lee, Nicholas G. Burgess, Michael J. Bourke
Summary: This study investigated the relationship between large nonpedunculated colorectal polyps (LNPCPs) and synchronous colonic LNPCPs, revealing that 6.9% of LNPCPs had synchronous lesions with a greater than 4-fold increased risk for non-granular LNPCPs.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
Mayenaaz Sidhu, Neal Shahidi, Sunil Gupta, Lobke Desomer, Sergei Vosko, W. Arnout van Hattem, Luke F. Hourigan, Eric Y. T. Lee, Alan Moss, Spiro Raftopoulos, Steven J. Heitman, Stephen J. Williams, Simon Zanati, David J. Tate, Nicholas Burgess, Michael J. Bourke
Summary: Thermal ablation of the defect margin after endoscopic mucosal resection (EMR-T) has been shown to significantly reduce residual or recurrent adenoma (RRA) at first surveillance colonoscopy. In an international multi-center prospective trial, EMR-T was found to be a simple, inexpensive, and highly effective auxiliary technique for managing large nonpedunculated colorectal polyps.
Article
Gastroenterology & Hepatology
Iddo Bar-Yishay, Neal Shahidi, Sunil Gupta, Sergei Vosko, W. Arnout van Hattem, Scott Schoeman, Mayenaaz Sidhu, David J. Tate, Luke F. Hourigan, Rajvinder Singh, Alan Moss, Spiro C. Raftopoulos, Gregor Brown, Simon Zanati, Steven J. Heitman, Eric Y. T. Lee, Nicholas Burgess, Stephen J. Williams, Karen Byth, Michael J. Bourke
Summary: The study evaluated the outcomes of intra-procedural deep mural injury (DMI) in large non-pedunculated colorectal polyps (LNPCPs) undergoing endoscopic mucosal resection (EMR). It found that significant DMI can be managed endoscopically with high success rates and does not impact technical success or recurrence.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Pediatrics
Valeria Dipasquale, Claudio Romano, Mauro Iannelli, Andrea Tortora, Alessandro Princiotta, Marco Ventimiglia, Giuseppinella Melita, Socrate Pallio
Summary: This study aimed to describe the frequency, major symptoms, and characteristics of colonic polyps in children. It found that lower gastrointestinal bleeding is the most common presentation, and right colonic polyps may be larger than left ones.
EUROPEAN JOURNAL OF PEDIATRICS
(2021)
Article
Surgery
Jeffrey D. E. Hawel, Rajni Patel, Terry Peters, Kerollos Wanis, Anish Naidu, Ran Xu, Ahmad Elnahas, Nawar A. Alkhamesi, Christopher M. Schlachta
Summary: The study found that attending physicians advance the scope during colonoscopy faster and with significantly less colonic displacement compared to resident trainees. Those who used torque steering also caused lower maximum colonic displacement than those who used knob steering.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Review
Gastroenterology & Hepatology
Sinan Sadalla, Andrea Lisotti, Lorenzo Fuccio, Pietro Fusaroli
Summary: Colonoscopy poses a risk for colon ischemia due to various factors such as impaired splanchnic circulation, medications used for sedation, bowel preparation, bowel wall ischemia from insufflation, and endoscope insertion. Gastroenterologists should be aware of these risk factors to minimize risks, facilitate early diagnosis, and administer appropriate treatment.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Biochemical Research Methods
Jonghee Yoon, James Joseph, Dale J. Waterhouse, Charlie Borzy, Kyla Siemens, Sarah Diamond, Vassiliki Liana Tsikitis, Sarah E. Bohndiek
Summary: The potential of a hyperspectral endoscope (HySE) to enhance polyp discrimination for detection and resection was evaluated through a proof-of-concept clinical study, where spectral data from patients undergoing routine colonoscopy screening were successfully collected and analyzed. The spectral data were discriminated by tissue type using spectral angle mapping and machine learning, showing the further research value of HySE as a clinical tool.
JOURNAL OF BIOPHOTONICS
(2021)
Article
Gastroenterology & Hepatology
Yu Mi Lee, Kyung Ho Song, Hoon Sup Koo, Choong-Sik Lee, Inseok Ko, Sang Hyuk Lee, Kyu Chan Huh
Summary: This study investigated whether the chicken skin mucosa (CSM) around colonic polyps can provide additional information about colorectal polyps. The results showed that CSM-positive polyps were associated with neoplastic and advanced polyps.
Article
Medicine, General & Internal
Yeo Wool Kang, Jong Hoon Lee, Jong Yoon Lee
Summary: This study evaluates the accuracy of predicting the histology of diminutive colonic polyps using i-scan OE based on the NICE classification. It compares the diagnostic accuracy between experts familiar with the NICE classification and trainees before and after training.
Article
Oncology
Tsung-Hsing Chen, Hung-Chih Hsu, Jeng-Fu You, Cheng-Chou Lai, Yung-Kuan Tsou, Chia-Lin Hsu, Cathy S. J. Fann, Rong-Nan Chien, Ming-Ling Chang
Summary: This 2-year prospective cohort study found a correlation between extracellular nicotinamide phosphoribosyltransferase (eNAMPT) and malignant potential in colonic polyps. Higher eNAMPT levels were observed in polyps with prominent malignant potential, and eNAMPT levels were associated with polyp pathology, total cholesterol, neutrophil-to-lymphocyte ratio, age, and polyp size. Additionally, eNAMPT levels decreased after polypectomy and could serve as a surrogate marker of malignant potential in colonic polyps.
Article
Health Care Sciences & Services
Ka Luen Thomas Lui, Sze Hang Kevin Liu, Kathy Leung, Joseph T. Wu, Ann G. Zauber, Wai Keung Leung
Summary: The widespread adoption of computer-aided detection (CADe) in detecting colorectal polyps would result in shorter surveillance intervals for patients, particularly according to the US Multi-Society Task Force on Colorectal Cancer (USMSTF) guideline. Based on simulation, CADe application would lead to approximately 19.1% and 1.9% of patients requiring shorter surveillance intervals, as recommended by the USMSTF and European Society of Gastrointestinal Endoscopy (ESGE) guidelines, respectively. Specifically, all or 2.7% of patients initially scheduled for 3-5 years of surveillance would have their intervals shortened to 3 years, according to the USMSTF guideline.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Review
Medicine, Research & Experimental
David E. F. W. M. van Toledo, Joep E. G. IJspeert, Evelien Dekker
Summary: Recent studies have shown that serrated polyps (SPs) also have the potential to develop into colorectal cancer, leading to a paradigm shift in CRC prevention, diagnosis, and treatment. While understanding of SPs and associated CRC has improved, there is still much work to be done in the clinical management of SPs and serrated polyposis syndrome (SPS).
ANNUAL REVIEW OF MEDICINE
(2022)
Article
Health Care Sciences & Services
Eun Jeong Gong, Chang Seok Bang, Jae Jun Lee, Young Joo Yang, Gwang Ho Baik
Summary: This study evaluated the impact of volume and distribution of training datasets on the development of a deep-learning model for predicting colorectal polyp histopathology from endoscopic images. The results showed that doubling the proportion of data for fewer categories improved the accuracy of the model. This research is important for the standardized creation of artificial intelligence models in gastrointestinal endoscopy.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Surgery
Jaimy A. Simmering, Steven J. G. Leeuwerke, Robbert Meerwaldt, Clark J. Zeebregts, Cornelis H. Slump, Robert H. Geelkerken
Summary: This article introduces a modified algorithm that quantifies changes in the geometry and motion of the aortic arch caused by cardiac pulsatility before and after double-branched endovascular repair. The algorithm has the potential to provide novel insights into the influence of bTEVAR on aortic anatomy, arterial compliance, and stent-graft dynamics.
JOURNAL OF ENDOVASCULAR THERAPY
(2023)
Article
Cardiac & Cardiovascular Systems
Majorie van Helvert, Jaimy A. Simmering, Maaike A. Koenrades, Cornelis H. Slump, Jan M. Heyligers, Robert H. Geelkerken, Michel M. Reijnen
Summary: This study analyzed the influence of IBE placement on the geometry of the CIA-IIA trajectory. The results showed that the placement of an IBE device stiffens and straightens the CIA-IIA trajectory, with a decrease in some geometric parameters. However, further research is needed to investigate the impact of IBE placement on clinical outcomes.
JOURNAL OF CARDIOVASCULAR SURGERY
(2022)
Article
Surgery
Jaimy A. Simmering, Mattijs de Vries, Marieke Haalboom, Michel M. P. J. Reijnen, Cornelis H. Slump, Robert H. Geelkerken
Summary: This study aimed to identify predictors for thromboembolic events (TE) in patients treated with the Anaconda stent-graft for infrarenal aneurysms. The study found that a decrease in curvature and tortuosity index (TI), and an increase in circumferential common iliac artery (CIA) calcification were associated with a lower risk of TE.
JOURNAL OF ENDOVASCULAR THERAPY
(2023)
Article
Multidisciplinary Sciences
Esteban Garcia-Gallo, Laura Merson, Kalynn Kennon, Sadie Kelly, Barbara Wanjiru Citarella, Daniel Vidali Fryer, Sally Shrapnel, James Lee, Sara Duque, Yuli V. Fuentes, Valeria Balan, Sue Smith, Jia Wei, Bronner P. Goncalves, Clark D. Russell, Louise Sigfrid, Andrew Dagens, Piero L. Olliaro, Joaquin Baruch, Christiana Kartsonaki, Jake Dunning, Amanda Rojek, Aasiyah Rashan, Abi Beane, Srinivas Murthy, Luis Felipe Reyes
Summary: The ISARIC COVID-19 dataset is one of the largest international databases of clinical data on hospitalized COVID-19 patients. It includes data from hospitals worldwide and provides comprehensive information on patient characteristics and treatments.
Article
Critical Care Medicine
Sharina Kort, Marjolein Brusse-Keizer, Hugo Schouwink, Emanuel Citgez, Frans H. de Jongh, Jan W. G. van Putten, Ben van den Borne, Elisabeth A. Kastelijn, Daiana Stolz, Milou Schuurbiers, Michel M. van den Heuvel, Wouter H. van Geffen, Job van der Palen
Summary: This study developed and validated a prediction model to distinguish patients with non-small cell lung cancer from non-lung cancer subjects using exhaled breath analysis. It also investigated the impact of adding clinical variables to improve the diagnosis. The results showed that combining exhaled breath data and clinical variables can effectively differentiate lung cancer patients from non-lung cancer subjects in a noninvasive manner, paving the way for the implementation of exhaled breath analysis in lung cancer diagnosis.
Article
Psychology, Clinical
Melissa C. Laurens, Marloes G. Postel, Marjolein Brusse-Keizer, Marcel E. Pieterse, Somaya Ben Allouch, Ernst T. Bohlmeijer, Elske Salemink
Summary: Previous research suggests that retraining the automatic tendency to approach alcohol can be effective in reducing problematic alcohol use. However, this study found that adding an online approach bias modification to outpatient treatment did not significantly reduce alcohol intake or other related outcomes. The lack of significant effects may be due to treatment goals and severity of alcohol use disorder.
ADDICTIVE BEHAVIORS
(2023)
Article
Medicine, General & Internal
Jaimy A. Simmering, Majorie Van Helvert, Joost A. Van Herwaarden, Cornelis H. Slump, Robert H. Geelkerken, Michel M. P. J. Reijnen
Summary: The relationship between stentgraft design of iliac branch devices (IBDs) and dynamic deformation is currently unknown. This study compared displacement and geometry changes during the cardiac cycle of two common IBDs. The results showed that IBDs had different displacement patterns and similar geometrical parameters, with the IBE showing more conformability than the ZBIS.
Article
Cardiac & Cardiovascular Systems
Frank R. Halfwerk, Nicole Wielens, Stephanie Hulskotte, Marjolein Brusse-Keizer, Jan G. Grandjean
Summary: The aim of this study was to evaluate early mobilization after heart surgery using a mobilization poster. The results showed that the poster improved mobility in patients, but there was no significant difference in the ACSM score.
JOURNAL OF CARDIOTHORACIC SURGERY
(2023)
Article
Gastroenterology & Hepatology
Floris W. Haijer, Cornelis B. Van Vliet, Marjolein G. J. Brusse-Keizer, Job A. M. van der Palen, Marjo J. Kerbert-Dreteler, Jeroen J. Kolkman
Summary: Itch frequently occurs in patients with chronic cholestasis, but the reason why some patients have pruritus and others do not is still unclear. A clinical observation found that cholestatic patients without itch had a relatively high serum gamma-glutamyl transpeptidase (GGT) compared to their serum bilirubin. This study aimed to validate this observation.
INTERNATIONAL JOURNAL OF HEPATOLOGY
(2023)
Article
Respiratory System
J. Schrijver, T. Effing, M. Brusse-Keizer, J. van der Palen, P. van der Valk, A. Lenferink
Summary: While exacerbation action plans have been proven to improve health outcomes in COPD patients, adherence to these plans is often poor. This study identified facilitators, such as improved comprehension of disease and positive feelings about the intervention, and barriers, such as difficulty in recognizing symptoms and dislike toward daily monitoring, to adherence. Patients had different perspectives on their own and healthcare professional's roles in disease management.
COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
(2023)
Review
Health Care Sciences & Services
Mattienne van der Kamp, Vera S. Hengeveld, Marjolein G. J. Brusse-Keizer, Boony J. Thio, Monique Tabak
Summary: This systematic scoping review explored the types and applications of eHealth technologies in monitoring and treatment of pediatric asthma. The results showed the potential efficacy of eHealth technologies, especially in medication monitoring, lung function, and digital environment domains. Future studies could focus on transferring relevant hospital-based diagnostics to the home setting and combining multiple home-monitoring domains for better decision-making and personalized clinical support.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Review
Medicine, General & Internal
Sanne H. B. van Dijk, Marjolein G. J. Brusse-Keizer, Charlotte C. Bucsan, Job van der Palen, Carine J. M. Doggen, Anke Lenferink
Summary: This article introduces how to use the AI tool 'ASReview' to conduct a transparent and reliable systematic review, which can accelerate the process and save time.
Article
Respiratory System
Sanne H. B. van Dijk, Marjolein G. J. Brusse-Keizer, Tanja Effing, Paul D. L. P. M. van der Valk, Eline H. Ploumen, Job van der Palen, Carine J. M. Doggen, Anke Lenferink
Summary: The study revealed that COPD patients with common comorbidities exhibit a variety of patterns of AECOPDs and comorbid flare-ups. Some patients show repetitive patterns that could potentially be utilized to enhance personalized disease management.
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
(2023)
Article
Surgery
Jaimy A. Simmering, Maaike A. Koenrades, Cornelis H. Slump, Erik Groot Jebbink, Clark J. Zeebregts, Michel M. P. J. Reijnen, Robert H. Geelkerken
Summary: This study analyzed the behavior of bridging stent configurations during fenestrated endovascular aortic aneurysm repair (FEVAR) for complex abdominal aortic aneurysms. The results showed stable configurations up to 12-month follow-up, except for an increase in renal branch angles.
JOURNAL OF ENDOVASCULAR THERAPY
(2023)
Article
Multidisciplinary Sciences
Bharath Kumar Tirupakuzhi Vijayaraghavan, Saptarshi Bishnu, Joaquin Baruch, Barbara Wanjiru Citarella, Christiana Kartsonaki, Aronrag Meeyai, Zubair Mohamed, Shinichiro Ohshimo, Benjamin Lefevre, Abdulrahman Al-Fares, Jose A. Calvache, Fabio Silvio Taccone, Piero Olliaro, Laura Merson, Neill K. J. Adhikari, ISARIC Clinical Characterisation Grp
Summary: Using a large dataset, this study evaluated the prevalence and severity of liver enzyme abnormalities in COVID-19 patients and found that these abnormalities are associated with worse outcomes.
