Leukemia-associated activating mutation of Flt3 expands dendritic cells and alters T cell responses

Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity

(2015) Santiago Zelenay et al.   CELL

Emerging Functions of Amphiregulin in Orchestrating Immunity, Inflammation, and Tissue Repair

(2015) Dietmar M.W. Zaiss et al.   IMMUNITY

Circulating precursors of human CD1c+and CD141+dendritic cells

(2015) Gaëlle Breton et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein

(2014) V. Bachanova et al.   BLOOD

Classical Flt3L-dependent dendritic cells control immunity to protein vaccine

(2014) Niroshana Anandasabapathy et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia

(2014) Liran I. Shlush et al.   NATURE

Monitoring dendritic cell and cytokine biomarkers during remission prior to relapse in patients with FLT3-ITD acute myeloid leukemia

(2013) Mareike Rickmann et al.   ANNALS OF HEMATOLOGY

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

Reducing TNF Receptor 2 + Regulatory T Cells via the Combined Action of Azacitidine and the HDAC Inhibitor, Panobinostat for Clinical Benefit in Acute Myeloid Leukemia Patients

(2013) Chindu Govindaraj et al.   CLINICAL CANCER RESEARCH

Clinical significance of Treg cell frequency in acute myeloid leukemia

(2013) Wenjuan Yang et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Antileukemic T-cell Responses Can Be Predicted by the Composition of Specific Regulatory T-cell Subpopulations

(2013) Julia Schick et al.   JOURNAL OF IMMUNOTHERAPY

Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Fms-Like Tyrosine Kinase 3 Ligand Controls Formation of Regulatory T Cells in Autoimmune Arthritis

(2013) Mattias N. D. Svensson et al.   PLoS One

FLT3-ITDs Instruct a Myeloid Differentiation and Transformation Bias in Lymphomyeloid Multipotent Progenitors

(2013) Adam J. Mead et al.   Cell Reports

FLT3-ITD Knockin Impairs Hematopoietic Stem Cell Quiescence/Homeostasis, Leading to Myeloproliferative Neoplasm

(2012) S. Haihua Chu et al.   Cell Stem Cell

Flt3 ligand expands CD4+FoxP3+regulatory T cells in human subjects

(2012) Oliver Klein et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Adrenomedullin, a neuropeptide with immunoregulatory properties induces semi-mature tolerogenic dendritic cells

(2012) Sandrine Rullé et al.   IMMUNOLOGY

Dendritic cells tolerized with adenosine A2AR agonist attenuate acute kidney injury

(2012) Li Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting the FMS-like tyrosine kinase 3 in acute myeloid leukemia

(2012) R Swords et al.   LEUKEMIA

Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia

(2012) Catherine C. Smith et al.   NATURE

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

(2012) Li Ding et al.   NATURE

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Clonal Evolution of Preleukemic Hematopoietic Stem Cells Precedes Human Acute Myeloid Leukemia

(2012) M. Jan et al.   Science Translational Medicine

Dendritic Cells: Arbiters of Immunity and Immunological Tolerance

(2012) K. L. Lewis et al.   Cold Spring Harbor Perspectives in Biology

Elevated frequencies of leukemic myeloid and plasmacytoid dendritic cells in acute myeloid leukemia with the FLT3 internal tandem duplication

(2011) Mareike Rickmann et al.   ANNALS OF HEMATOLOGY

Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation

(2011) S. Kharazi et al.   BLOOD

STAT5A-Mediated SOCS2 Expression Regulates Jak2 and STAT3 Activity Following c-Src Inhibition in Head and Neck Squamous Carcinoma

(2011) B. Sen et al.   CLINICAL CANCER RESEARCH

Flt3 ligand expands CD103+dendritic cells and FoxP3+T regulatory cells, and attenuates Crohn's-like murine ileitis

(2011) Colm B Collins et al.   GUT

CD8α+ Dendritic Cells Are an Obligate Cellular Entry Point for Productive Infection by Listeria monocytogenes

(2011) Brian T. Edelson et al.   IMMUNITY

Notch2 Receptor Signaling Controls Functional Differentiation of Dendritic Cells in the Spleen and Intestine

(2011) Kanako L. Lewis et al.   IMMUNITY

Dendritic cells induce antigen-specific regulatory T cells that prevent graft versus host disease and persist in mice

(2011) Uri Sela et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Further activation of FLT3 mutants by FLT3 ligand

(2011) R Zheng et al.   ONCOGENE

FLT3 as a therapeutic target in AML: still challenging after all these years

(2010) T. Kindler et al.   BLOOD

Dendritic cell-restricted CD80/86 deficiency results in peripheral regulatory T-cell reduction but is not associated with lymphocyte hyperactivation

(2010) Liat Bar-On et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mammalian Target of Rapamycin Controls Dendritic Cell Development Downstream of Flt3 Ligand Signaling

(2010) Taheri Sathaliyawala et al.   IMMUNITY

Origin and development of dendritic cells

(2010) Kang Liu et al.   IMMUNOLOGICAL REVIEWS

CX3CR1+ CD8 + dendritic cells are a steady-state population related to plasmacytoid dendritic cells

(2010) L. Bar-On et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of Monocytes, Macrophages, and Dendritic Cells

(2010) F. Geissmann et al.   SCIENCE

Expansion of peripheral naturally occurring T regulatory cells by Fms-like tyrosine kinase 3 ligand treatment

(2009) L. K. Swee et al.   BLOOD

Intestinal Lamina Propria Dendritic Cell Subsets Have Different Origin and Functions

(2009) Chen Varol et al.   IMMUNITY

The origin and development of nonlymphoid tissue CD103+DCs

(2009) Florent Ginhoux et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Feedback control of regulatory T cell homeostasis by dendritic cells in vivo

(2009) Guillaume Darrasse-Jèze et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues

(2008) Claudia Waskow et al.   NATURE IMMUNOLOGY

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

(2008) K. Hildner et al.   SCIENCE