Senp1 drives hypoxia-induced polycythemia via GATA1 and Bcl-xL in subjects with Monge’s disease

SENP1 inhibition induces apoptosis and growth arrest of multiple myeloma cells through modulation of NF-κB signaling

(2015) Jun Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Increased SUMO-1 expression in response to hypoxia: Interaction with HIF-1α in hypoxic pulmonary hypertension

(2015) YONGLIANG JIANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Altered iPSC-derived neurons’ sodium channel properties in subjects with Monge’s disease

(2015) H.W. Zhao et al.   NEUROSCIENCE

Endothelin receptor B, a candidate gene from human studies at high altitude, improves cardiac tolerance to hypoxia in genetically engineered heterozygote mice

(2015) Tsering Stobdan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Predicting Carriers of Ongoing Selective Sweeps without Knowledge of the Favored Allele

(2015) Roy Ronen et al.   PLoS Genetics

A Facile Method to Establish Human Induced Pluripotent Stem Cells From Adult Blood Cells Under Feeder-Free and Xeno-Free Culture Conditions: A Clinically Compliant Approach

(2015) Bin-Kuan Chou et al.   Stem Cells Translational Medicine

Higher androgen bioactivity is associated with excessive erythrocytosis and chronic mountain sickness in Andean Highlanders: a review

(2014) G. F. Gonzales et al.   ANDROLOGIA

Chronic mountain sickness in Chinese Han males who migrated to the Qinghai-Tibetan plateau: application and evaluation of diagnostic criteria for chronic mountain sickness

(2014) Chunhua Jiang et al.   BMC PUBLIC HEALTH

Genetic Variation in SENP1 and ANP32D as Predictors of Chronic Mountain Sickness

(2014) Amy M. Cole et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

Decreased plasma soluble erythropoietin receptor in high-altitude excessive erythrocytosis and Chronic Mountain Sickness

(2014) Francisco C. Villafuerte et al.   JOURNAL OF APPLIED PHYSIOLOGY

‘Ome’ on the range: update on high-altitude acclimatization/adaptation and disease

(2014) Yongjun Luo et al.   Molecular BioSystems

Wnt signaling controls the specification of definitive and primitive hematopoiesis from human pluripotent stem cells

(2014) Christopher M Sturgeon et al.   NATURE BIOTECHNOLOGY

A genetic mechanism for Tibetan high-altitude adaptation

(2014) Felipe R Lorenzo et al.   NATURE GENETICS

The Genetic Basis of Chronic Mountain Sickness

(2014) Roy Ronen et al.   PHYSIOLOGY

Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes

(2014) Nitin Udpa et al.   GENOME BIOLOGY

Whole-Genome Sequencing Uncovers the Genetic Basis of Chronic Mountain Sickness in Andean Highlanders

(2013) Dan Zhou et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Erythrocytosis: the HIF pathway in control

(2013) K. Franke et al.   BLOOD

Regulation of erythropoiesis by hypoxia-inducible factors

(2013) Volker H. Haase   BLOOD REVIEWS

Pulmonary Hypertension and Chronic Mountain Sickness

(2013) Robert Naeije et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

Identification of a Tibetan-Specific Mutation in the Hypoxic Gene EGLN1 and Its Contribution to High-Altitude Adaptation

(2013) Kun Xiang et al.   MOLECULAR BIOLOGY AND EVOLUTION

Human induced pluripotent stem cells can reach complete terminal maturation: in vivo and in vitro evidence in the erythropoietic differentiation model

(2012) L. Kobari et al.   HAEMATOLOGICA

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

The Genetic Architecture of Adaptations to High Altitude in Ethiopia

(2012) Gorka Alkorta-Aranburu et al.   PLoS Genetics

Genetic adaptation to high altitude in the Ethiopian highlands

(2012) Laura B Scheinfeldt et al.   GENOME BIOLOGY

ENCODE whole-genome data in the UCSC Genome Browser: update 2012

(2011) K. R. Rosenbloom et al.   NUCLEIC ACIDS RESEARCH

Brain Blood Flow in Andean and Himalayan High-Altitude Populations: Evidence of Different Traits for the Same Environmental Constraint

(2010) Gerard FA Jansen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis

(2010) Luyang Yu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Physiological Adaptation of the Cardiovascular System to High Altitude

(2010) Robert Naeije   PROGRESS IN CARDIOVASCULAR DISEASES

Genetic Evidence for High-Altitude Adaptation in Tibet

(2010) T. S. Simonson et al.   SCIENCE

Gene Expression in Chronic High Altitude Diseases

(2008) Fabiola León-Velarde et al.   HIGH ALTITUDE MEDICINE & BIOLOGY