TET3 inhibits TGF-β1-induced epithelial-mesenchymal transition by demethylating miR-30d precursor gene in ovarian cancer cells

miR-30d Blocked Transforming Growth Factor β1–Induced Epithelial-Mesenchymal Transition by Targeting Snail in Ovarian Cancer Cells

(2015) Zhongxue Ye et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Clinical significance of DNA methylation mRNA levels of TET family members in colorectal cancer

(2015) Agnieszka Anna Rawłuszko-Wieczorek et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

TET2 repression by androgen hormone regulates global hydroxymethylation status and prostate cancer progression

(2015) Ken-ichi Takayama et al.   Nature Communications

TGF-β1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma

(2015) Fangfang Bu et al.   Oncotarget

TGF-β induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cells

(2014) Horacio Cardenas et al.   Epigenetics

Tumor suppression by miR-26 overrides potential oncogenic activity in intestinal tumorigenesis

(2014) Lauren R. Zeitels et al.   GENES & DEVELOPMENT

Promoter methylation of tumor suppressor genes in pre-neoplastic lesions; potential marker of disease recurrence

(2014) Claudia Rengucci et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Central role of Snail1 in the regulation of EMT and resistance in cancer: a target for therapeutic intervention

(2014) Samantha Kaufhold et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

miR-29b as a Therapeutic Agent for Angiotensin II-induced Cardiac Fibrosis by Targeting TGF-β/Smad3 signaling

(2014) Yang Zhang et al.   MOLECULAR THERAPY

Ten-eleven translocation (Tet) and thymine DNA glycosylase (TDG), components of the demethylation pathway, are direct targets of miRNA-29a

(2013) Pei Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Stage-Specific Roles for Tet1 and Tet2 in DNA Demethylation in Primordial Germ Cells

(2013) John J. Vincent et al.   Cell Stem Cell

Targeting TGF-β signaling in cancer

(2013) Lior H Katz et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Involvement of miRNA-29a in epigenetic regulation of transforming growth factor-β-induced epithelial-mesenchymal transition in hepatocellular carcinoma

(2013) Takayuki Kogure et al.   HEPATOLOGY RESEARCH

miR-29 Represses the Activities of DNA Methyltransferases and DNA Demethylases

(2013) Sumiyo Morita et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency

(2013) Yael Costa et al.   NATURE

MicroRNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiation

(2013) X. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Extensive Network of TET2-Targeting MicroRNAs Regulates Malignant Hematopoiesis

(2013) Jijun Cheng et al.   Cell Reports

Nuclear Exclusion of TET1 Is Associated with Loss of 5-Hydroxymethylcytosine in IDH1 Wild-Type Gliomas

(2012) Tim Müller et al.   AMERICAN JOURNAL OF PATHOLOGY

Loss of 5-Hydroxymethylcytosine Is an Epigenetic Hallmark of Melanoma

(2012) Christine Guo Lian et al.   CELL

Cancer Epigenetics: From Mechanism to Therapy

(2012) Mark A. Dawson et al.   CELL

Global profiling of DNA methylation erasure in mouse primordial germ cells

(2012) S. Guibert et al.   GENOME RESEARCH

Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation

(2012) H Yang et al.   ONCOGENE

TET1 Suppresses Cancer Invasion by Activating the Tissue Inhibitors of Metalloproteinases

(2012) Chih-Hung Hsu et al.   Cell Reports

TGF-β Regulates DNA Methyltransferase Expression in Prostate Cancer, Correlates with Aggressive Capabilities, and Predicts Disease Recurrence

(2011) Qiang Zhang et al.   PLoS One

Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine

(2011) Khursheed Iqbal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

(2011) S. Ito et al.   SCIENCE

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

(2010) Myunggon Ko et al.   NATURE

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

(2010) Shinsuke Ito et al.   NATURE

Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies

(2009) O. Abdel-Wahab et al.   BLOOD

The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo

(2009) J. T. Huse et al.   GENES & DEVELOPMENT

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE