Pepsin and the Lung—Exploring the Relationship between Micro-Aspiration and Respiratory Manifestations of Gastroesophageal Reflux Disease

Positive bronchoalveolar lavage pepsin assay associated with viral and fungal respiratory infections in children with chronic cough

(2021) Corey N. Martin et al.   PEDIATRIC PULMONOLOGY

The Controversy of Pepsinogen A/Pepsin A in Detecting Extra-Gastroesophageal Reflux

(2021) Yu-fang Rao et al.   JOURNAL OF VOICE

Randomised trials of proton pump inhibitors for gastro-oesophageal reflux disease in patients with asthma: an updated systematic review and meta-analysis

(2021) Zhoude Zheng et al.   BMJ Open

Extra-Esophageal Presentation of Gastroesophageal Reflux Disease: 2020 Update

(2020) Marilena Durazzo et al.   Journal of Clinical Medicine

The global, regional, and national burden of gastro-oesophageal reflux disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2020) M Ashworth Dirac et al.   Lancet Gastroenterology & Hepatology

Pepsin exposure in a non‐acidic environment upregulates mucin 5AC (MUC5AC) expression via matrix metalloproteinase 9 (MMP9)/nuclear factor κB (NF‐κB) in human airway epithelial cells

(2020) Yoon Seok Choi et al.   International Forum of Allergy & Rhinology

Gastric Acid and Pepsin Work Together in Simulated Gastric Acid Inhalation Leading to Pulmonary Fibrosis in Rats

(2019) Shi Chen et al.   MEDICAL SCIENCE MONITOR

Pepsin Triggers Neutrophil Migration Across Acid Damaged Lung Epithelium

(2019) Bryan P. Hurley et al.   Scientific Reports

Pathophysiology of Gastroesophageal Reflux Disease

(2018) Jan Tack et al.   GASTROENTEROLOGY

The Changing Epidemiology of Gastroesophageal Reflux Disease: Are Patients Getting Younger?

(2018) Takahisa Yamasaki et al.   Journal of Neurogastroenterology and Motility

Clinical Utility of Bronchoalveolar Lavage Pepsin in Diagnosis of Gastroesophageal Reflux among Wheezy Infants

(2016) Ahmed Fathi Abdallah et al.   Canadian Respiratory Journal

Salivary Pepsin Lacks Sensitivity as a Diagnostic Tool to Evaluate Extraesophageal Reflux Disease

(2016) Fei Dy et al.   JOURNAL OF PEDIATRICS

Detection of pepsin in sputum: a rapid and objective measure of airways reflux

(2015) Vicki Strugala et al.   EUROPEAN RESPIRATORY JOURNAL

Exhaled Breath Condensate Pepsin: Potential Noninvasive Test for Gastroesophageal Reflux in COPD and Bronchiectasis

(2014) A. L. Lee et al.   Respiratory Care

The diagnostic value of gastroesophageal reflux disease (GERD) symptoms and detection of pepsin and bile acids in bronchoalveolar lavage fluid and exhaled breath condensate for identifying lung transplantation patients with GERD-induced aspiration

(2014) Nicholas P. Reder et al.   SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES

Aspiration and Allograft Injury Secondary to Gastroesophageal Reflux Occur in the Immediate Post–Lung Transplantation Period (Prospective Clinical Trial)

(2013) S. Michael Griffin et al.   ANNALS OF SURGERY

Association of gastroesophageal reflux disease risk with exacerbations of chronic obstructive pulmonary disease

(2013) B. Liang et al.   DISEASES OF THE ESOPHAGUS

Pepsin levels and oxidative stress markers in exhaled breath condensate of patients with gastroesophageal reflux disease

(2013) Tutku Soyer et al.   JOURNAL OF PEDIATRIC SURGERY

Aspiration, Localized Pulmonary Inflammation, and Predictors of Early-Onset Bronchiolitis Obliterans Syndrome after Lung Transplantation

(2013) P. Marco Fisichella et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Proximal and distal gastro-oesophageal reflux in chronic obstructive pulmonary disease and bronchiectasis

(2013) Annemarie L. Lee et al.   RESPIROLOGY

Chronic Cough

(2012) Samantha Decalmer et al.   CHEST

Association of gastroesophageal reflux disease with asthma control

(2012) B. Liang et al.   DISEASES OF THE ESOPHAGUS

Detection of gastro-oesophageal reflux disease (GORD) in patients with obstructive lung disease using exhaled breath profiling

(2012) Chris Timms et al.   Journal of Breath Research

Clinical Features of Asthma in Children Differ with Regard to the Intensity of Distal Gastroesophageal Acid Reflux

(2011) Jaroslaw Kwiecien et al.   JOURNAL OF ASTHMA

The presence of pepsin in the lung and its relationship to pathologic gastro-esophageal reflux

(2011) R. Rosen et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Prospective evaluation of the relationship between acute exacerbations of COPD and gastroesophageal reflux disease diagnosed by questionnaire

(2011) Kazuto Takada et al.   RESPIRATORY MEDICINE

Pepsin and bile acids in induced sputum of chronic cough patients

(2011) Marcin Grabowski et al.   RESPIRATORY MEDICINE

The protective role of laparoscopic antireflux surgery against aspiration of pepsin after lung transplantation

(2011) P. Marco Fisichella et al.   SURGERY

Effect of Esomeprazole 40 mg Once or Twice Daily on Asthma

(2010) Toni O. Kiljander et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Acoustic Cough—Reflux Associations in Chronic Cough: Potential Triggers and Mechanisms

(2010) Jaclyn A. Smith et al.   GASTROENTEROLOGY

Gastric Juice From Patients “On” Acid Supressive Therapy Can Still Provoke a Significant Inflammatory Reaction by Human Bronchial Epithelial Cells

(2010) Veerle Mertens et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease

(2010) John R. Hurst et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gastro-oesophageal reflux and gastric aspiration in lung transplant patients with or without chronic rejection

(2007) K. Blondeau et al.   EUROPEAN RESPIRATORY JOURNAL