Article
Cardiac & Cardiovascular Systems
Akito Nakagawa, Yoshio Yasumura, Chikako Yoshida, Takahiro Okumura, Jun Tateishi, Junichi Yoshida, Shunsuke Tamaki, Masamichi Yano, Takaharu Hayashi, Yusuke Nakagawa, Takahisa Yamada, Daisaku Nakatani, Shungo Hikoso, Yasushi Sakata
Summary: The study found that patients with preserved admission SBP had a higher risk for adverse outcomes of cardiac death and heart failure re-hospitalization in HFpEF. Compared to patients with elevated admission SBP, those with preserved SBP had a higher risk of poor prognosis.
Article
Cardiac & Cardiovascular Systems
Xavier Rossello, Hector Bueno, Victor Gil, Javier Jacob, Francisco Javier Martin-Sanchez, Pere Llorens, Pablo Herrero Puente, Aitor Alquezar-Arbe, Begona Espinosa, Sergio Raposeiras-Roubin, Christian E. Muller, Alexandre Mebazaa, Aldo P. Maggioni, Stuart Pocock, Ovidiu Chioncel, Oscar Miro
Summary: The study found that in patients with acute heart failure, 30-day mortality is closely associated with systolic blood pressure and manifestations of hypoperfusion, with hypoperfusion increasing the risk of 30-day all-cause mortality not only in patients with low systolic blood pressure but also in normotensive patients. On admission, physical examination plays a major role in determining prognosis in patients with acute heart failure.
CIRCULATION-HEART FAILURE
(2021)
Article
Cardiac & Cardiovascular Systems
Nisha A. Gilotra, Adam D. DeVore, Thomas J. Povsic, Allison G. Hays, Virginia S. Hahn, Tolu A. Agunbiade, Allison DeLong, Andrew Satlin, Richard Chen, Robert Davis, David A. Kass
Summary: The study evaluated the effects of single-dose ITI-214 in patients with heart failure, showing good tolerability and positive inotropic effects in patients with reduced ejection fraction.
CIRCULATION-HEART FAILURE
(2021)
Article
Cardiac & Cardiovascular Systems
Johannes Grand, Kristina Miger, Ahmad Sajadieh, Lars Kober, Christian Torp-Pedersen, Georg Ertl, Jose Lopez-Sendon, Aldo Pietro Maggioni, John R. Teerlink, Naoki Sato, Claudio Gimpelewicz, Marco Metra, Thomas Holbro, Olav W. Nielsen
Summary: This study found that in patients with acute heart failure, systolic blood pressure (SBP) is associated with short-term and long-term outcomes, with different effects observed in patients with left ventricular ejection fraction (LVEF) <40% and LVEF >= 40%.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Xinghe Huang, Jiamin Liu, Lihua Zhang, Bin Wang, Xueke Bai, Shuang Hu, Fengyu Miao, Aoxi Tian, Tingxuan Yang, Yan Li, Jing Li
Summary: This study investigated the association between systolic blood pressure (SBP) and long-term clinical outcomes in patients hospitalized for heart failure (HF). The findings showed that lower SBP during hospitalization was associated with an increased risk of 1-year death, and there was a J-curve relationship between SBP and 1-year HF readmission. These associations were consistent across important clinical subgroups.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Xinghe Huang, Jiamin Liu, Shuang Hu, Lihua Zhang, Fengyu Miao, Aoxi Tian, Jing Li
Summary: The study aimed to investigate the association between admission systolic blood pressure (SBP) and 1-year clinical outcomes in patients hospitalized for heart failure (HF). The findings revealed that lower admission SBP was significantly associated with higher all-cause death and HF readmission risk within 1 year, and these associations were consistent across different subgroups.
Article
Urology & Nephrology
Hirofumi Sumi, Akari Ishii, Yuki Yamada, Yugo Shibagaki, Naoto Tominaga
Summary: This case report highlights the rare detection of central volume shift as a major pathophysiological mechanism of acute pulmonary oedema in acute heart failure during haemodialysis. The inverse correlation of blood volume and blood pressure during haemodialysis suggests that the theoretical central volume shift was captured in real-world AHF.
CLINICAL KIDNEY JOURNAL
(2022)
Article
Cardiac & Cardiovascular Systems
Michael Boehm, Stefan D. Anker, Javed Butler, Gerasimos Filippatos, Joao Pedro Ferreira, Stuart J. Pocock, Felix Mahfoud, Martina Brueckmann, Waheed Jamal, Anne Pernille Ofstad, Elke Schueler, Piotr Ponikowski, Christoph Wanner, Faiez Zannad, Milton Packer
Summary: Empagliflozin was found to be effective and safe in patients with reduced ejection fraction heart failure, with no significant interaction between systolic blood pressure and the drug's effects. Patients with baseline systolic blood pressure <110 mm Hg did not experience an increased rate of symptomatic hypotension when treated with empagliflozin.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Peripheral Vascular Disease
Yujian Wu, Zhuoyan Li, Bowen Du, Yujiao Ye, Hualin Wang, Yiwei Niu, Sun Chen, Yurong Wu, Hong Jin, Xi Zhang, Jian Wang, Kun Sun
Summary: This study investigated the associations of systolic blood pressure (SBP) and body mass index (BMI) with cardiovascular structure and function in 4-year-old children. The results showed that elevated SBP and BMI were related to cardiac structure and function in these children. SBP was positively related to heart rate and left ventricular ejection fraction, while BMI was positively associated with left ventricular mass index and the risk of left ventricular hypertrophy, but negatively related to measures of systolic function. No significant interactions between BMI and SBP were detected.
Article
Peripheral Vascular Disease
Orna Reges, Hongyan Ning, John T. Wilkins, Colin O. Wu, Xin Tian, Michael J. Domanski, Donald M. Lloyd-Jones, Norrina B. Allen
Summary: This study assessed the association between 10-year cumulative systolic blood pressure in middle age and long-term risk of cardiovascular disease, coronary heart disease, stroke, heart failure, and all-cause mortality. Lower 10-year cumulative systolic blood pressure was found to be associated with longer survival and a later onset of cardiovascular disease, highlighting its importance as a risk factor for CVD beyond current systolic blood pressure levels.
Article
Cardiac & Cardiovascular Systems
Sophie Putot, Arthur Hacquin, Patrick Manckoundia, Alain Putot
Summary: Intensive SBP control below 130 mmHg at discharge was not associated with better survival in very old adults hospitalized for acute HFpEF, but prescribing antihypertensive drugs at discharge was associated with significantly reduced mortality and re-hospitalization rates.
Article
Cardiac & Cardiovascular Systems
Sophie Putot, Arthur Hacquin, Patrick Manckoundia, Alain Putot
Summary: Intensive systolic blood pressure control below 130 mmHg at discharge was not associated with improved survival in very old adults hospitalized for acute HFpEF, but prescribing antihypertensive drugs at discharge was linked to reduced mortality and re-hospitalization rates by half. Future prospective studies are necessary to evaluate target blood pressure in very elderly patients with HFpEF.
Article
Peripheral Vascular Disease
Leo F. Buckley, William L. Baker, Benjamin W. Van Tassell, Jordana B. Cohen, Omar Alkhezi, Adam P. Bress, Dave L. Dixon
Summary: The study found that the amount of time spent within the target range for blood pressure is associated with adverse kidney and cardiovascular events. Better blood pressure control in hypertensive patients is linked to a lower risk of kidney and cardiovascular problems.
Article
Cardiac & Cardiovascular Systems
Rihua Huang, Yifen Lin, Menghui Liu, Zhenyu Xiong, Shaozhao Zhang, Xiangbin Zhong, Xiaomin Ye, Yiquan Huang, Xiaodong Zhuang, Xinxue Liao
Summary: This study found that longer time in target range of systolic blood pressure was statistically associated with a decreased risk of cardiovascular outcomes and mortality events among patients with heart failure with preserved ejection fraction. This association was more significant in younger patients.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Peripheral Vascular Disease
Thomas Weber, Athanase D. Protogerou, Mohsen Agharazii, Antonis Argyris, Sola Aoun Bahous, Jose R. Banegas, Ronald K. Binder, Jacques Blacher, Andrea Araujo Brandao, Juan J. Cruz, Kathrin Danninger, Cristina Giannatasio, Auxiliadora Graciani, Bernhard Hametner, Piotr Jankowski, Yan Li, Alessandro Maloberti, Christopher C. Mayer, Barry J. McDonnell, Carmel M. McEniery, Marco Antonio Mota Gomes, Annelise Machado Gomes, Maria Lorenza Muiesan, Janos Nemcsik, Anna Paini, Enrique Rodilla, Aletta E. Schutte, Petros P. Sfikakis, Dimitrios Terentes-Printzios, Alexandre Vallee, Charalambos Vlachopoulos, Lisa Ware, Ian Wilkinson, Robert Zweiker, James E. Sharman, Siegfried Wassertheurer
Summary: Central systolic blood pressure (cSBP) is more closely associated with hypertension-mediated organ damage and prognosis than brachial systolic blood pressure. This study investigated the 24-hour profiles of brachial and central SBP in untreated adults, providing reference values and analyzing daytime-nighttime variability. The findings have potential implications for refining hypertension diagnosis and management.