Management of Preschool Wheezing: Guideline from the Emilia-Romagna Asthma (ERA) Study Group

Combination of ipratropium bromide and salbutamol in children and adolescents with asthma: A meta-analysis

(2021) Hongzhen Xu et al.   PLoS One

The Airway Microbiota Modulates Effect of Azithromycin Treatment for Episodes of Recurrent Asthma-like Symptoms in Preschool Children: A Randomized Clinical Trial

(2021) Jonathan Thorsen et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Effects of using montelukast during acute wheezing attack in hospitalized preschool children on the discharge rate and the clinical asthma score

(2021) Emine Demet Akbaş et al.   PEDIATRIC PULMONOLOGY

Role of montelukast in multitrigger wheezers attending chest clinic in Punjab, India

(2021) Gursavreen K. Kahlon et al.   PEDIATRIC PULMONOLOGY

Treatment of pediatric mild persistent asthma with low-dose budesonide inhalation suspension vs. montelukast in China

(2021) Zhi-Min Chen et al.   World Journal of Pediatrics

Management of Children with Acute Asthma Attack: A RAND/UCLA Appropriateness Approach

(2021) Valentina Fainardi et al.   International Journal of Environmental Research and Public Health

Nebulized Inhaled Corticosteroids in Asthma Treatment in Children ≤5 Years of Age: A Systematic Review and Global Expert Analysis

(2020) Jian Guo Hong et al.   Journal of Allergy and Clinical Immunology-In Practice

Association between early antibiotic treatment and clinical outcomes in children hospitalized for asthma exacerbation

(2020) Yusuke Okubo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Impact of oral corticosteroids on respiratory outcomes in acute preschool wheeze: a randomised clinical trial

(2020) Alexandra Wallace et al.   ARCHIVES OF DISEASE IN CHILDHOOD

2020 Focused Updates to the Asthma Management Guidelines: A Report from the National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group

(2020) Michelle M. Cloutier et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Healthcare utilization in infants and toddlers with asthma‐like symptoms

(2019) Hagit Levine et al.   PEDIATRIC PULMONOLOGY

Comparative effectiveness of budesonide inhalation suspension and montelukast in children with mild asthma in Korea

(2019) Jina Shin et al.   JOURNAL OF ASTHMA

Azithromycin is the answer in Paediatric Respiratory Medicine, but what was the question?

(2019) Andrew Bush   Paediatric Respiratory Reviews

Safety of corticosteroids in young children with acute respiratory conditions: a systematic review and meta-analysis

(2019) Ricardo M Fernandes et al.   BMJ Open

Pediatric asthma: Principles and treatment

(2019) Ashley L. Devonshire et al.   ALLERGY AND ASTHMA PROCEEDINGS

The infant and toddler with wheezing

(2019) Nurcicek Padem et al.   ALLERGY AND ASTHMA PROCEEDINGS

Question 4: Is there a role for antibiotics in infantile wheeze?

(2019) Fernando M. de Benedictis et al.   Paediatric Respiratory Reviews

Management of Recurrent Preschool, Doctor-Diagnosed Wheeze

(2018) Ka-ka Siu et al.   INDIAN JOURNAL OF PEDIATRICS

Oral corticosteroids in preschool children with severe episodes of virus-associated wheeze: to treat or not to treat?

(2018) Avraham Beigelman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Early control treatment with montelukast in preschool children with asthma: A randomized controlled trial

(2018) Mizuho Nagao et al.   ALLERGOLOGY INTERNATIONAL

Should oral corticosteroids be prescribed for preschool viral wheeze?

(2018) Sejal Saglani et al.   Lancet Respiratory Medicine

Safety and efficacy of tiotropium in children aged 1–5 years with persistent asthmatic symptoms: a randomised, double-blind, placebo-controlled trial

(2018) Elianne J L E Vrijlandt et al.   Lancet Respiratory Medicine

Oral prednisolone in preschool children with virus-associated wheeze: a prospective, randomised, double-blind, placebo-controlled trial

(2018) S J Foster et al.   Lancet Respiratory Medicine

The efficacy and safety of fluticasone salmeterol compared to fluticasone in children younger than four years of age

(2018) Shigemi Yoshihara et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Daily inhaled corticosteroids or montelukast for preschoolers with asthma or recurrent wheezing: A systematic review

(2018) Jose A. Castro-Rodriguez et al.   PEDIATRIC PULMONOLOGY

A meta-analysis of montelukast for recurrent wheeze in preschool children

(2017) Hasan R. Hussein et al.   EUROPEAN JOURNAL OF PEDIATRICS

Temporal stability of multitrigger and episodic viral wheeze in early childhood

(2017) Ben D. Spycher et al.   EUROPEAN RESPIRATORY JOURNAL

Montelukast Treatment of Acute Asthma Exacerbations in Children Aged 2 to 5 Years

(2017) Xiuping Wang et al.   PEDIATRIC EMERGENCY CARE

Treatment of preschool children presenting to the emergency department with wheeze with azithromycin: A placebo-controlled randomized trial

(2017) Piush J. Mandhane et al.   PLoS One

Inhaled short-acting bronchodilators for managing emergency childhood asthma: an overview of reviews

(2016) M. Pollock et al.   ALLERGY

Salbutamol in paediatrics: pharmacology, prescribing and controversies

(2016) Paul Andrzejowski et al.   Archives of Disease in Childhood-Education and Practice Edition

Stability and predictiveness of multiple trigger and episodic viral wheeze in preschoolers

(2016) K. E. van Wonderen et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Individualized therapy for persistent asthma in young children

(2016) Anne M. Fitzpatrick et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Efficacy of oral corticosteroids in the treatment of acute wheezing episodes in asthmatic preschoolers: Systematic review with meta-analysis

(2016) Jose A. Castro-Rodriguez et al.   PEDIATRIC PULMONOLOGY

Preventing Exacerbations in Preschoolers With Recurrent Wheeze: A Meta-analysis

(2016) S. V. Kaiser et al.   PEDIATRICS

Azithromycin for episodes with asthma-like symptoms in young children aged 1–3 years: a randomised, double-blind, placebo-controlled trial

(2016) Jakob Stokholm et al.   Lancet Respiratory Medicine

Should a Preschool Child with Acute Episodic Wheeze be Treated with Oral Corticosteroids? A Pro/Con Debate

(2016) Avraham Beigelman et al.   Journal of Allergy and Clinical Immunology-In Practice

Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses

(2015) Leonard B. Bacharier et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effectiveness of drug treatment strategies to prevent asthma exacerbations and increase symptom-free days in asthmatic children: a network meta-analysis

(2015) Yile Zhao et al.   JOURNAL OF ASTHMA

Inhibition of Common Cold-Induced Aggravation of Childhood Asthma by Leukotriene Receptor Antagonists

(2015) Shigemi Yoshihara et al.   ALLERGOLOGY INTERNATIONAL

Fluticasone or Montelukast in Preschool Wheeze

(2014) Marta Krawiec et al.   CLINICAL PEDIATRICS

Classification and pharmacological treatment of preschool wheezing: changes since 2008

(2014) P. L. P. Brand et al.   EUROPEAN RESPIRATORY JOURNAL

Pharmacological approach to wheezing in preschool children

(2014) Susanna Esposito et al.   EXPERT OPINION ON PHARMACOTHERAPY

Montelukast versus Budesonide as a First Line Preventive Therapy in Mild Persistent Asthma in 2 to 18 y

(2014) Monil Bharat Shah et al.   INDIAN JOURNAL OF PEDIATRICS

Principal findings of systematic reviews for chronic treatment in childhood asthma

(2014) Jose A. Castro-Rodriguez et al.   JOURNAL OF ASTHMA

Metered-dose inhaler ipratropium bromide in moderate acute asthma in children: A single-blinded randomised controlled trial

(2014) Emma L Wyatt et al.   JOURNAL OF PAEDIATRICS AND CHILD HEALTH

Diagnosis, management, and prognosis of preschool wheeze

(2014) Francine M Ducharme et al.   LANCET

Effectiveness of Nebulized Beclomethasone in Preventing Viral Wheezing: An RCT

(2014) A. Clavenna et al.   PEDIATRICS

Intermittent montelukast in children aged 10 months to 5 years with wheeze (WAIT trial): a multicentre, randomised, placebo-controlled trial

(2014) Chinedu Nwokoro et al.   Lancet Respiratory Medicine

Use of Leukotriene Receptor Antagonists Are Associated with a Similar Risk of Asthma Exacerbations as Inhaled Corticosteroids

(2014) Ann Chen Wu et al.   Journal of Allergy and Clinical Immunology-In Practice

Short-term follow-up of episodic wheeze and predictive factors for persistent wheeze

(2013) E. Topal et al.   ALLERGY AND ASTHMA PROCEEDINGS

Do oral corticosteroids reduce the severity of acute lower respiratory tract illnesses in preschool children with recurrent wheezing?

(2013) Avraham Beigelman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A simple asthma prediction tool for preschool children with wheeze or cough

(2013) Anina M. Pescatore et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

GRADE guidelines: 15. Going from evidence to recommendation—determinants of a recommendation's direction and strength

(2013) Jeffrey C. Andrews et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Demographic Predictors of Leukotriene Antagonist Monotherapy Among Children with Persistent Asthma

(2013) Chang L. Wu et al.   JOURNAL OF PEDIATRICS

Validation of novel wheeze phenotypes using longitudinal airway function and atopic sensitization data in the first 6 years of life: Evidence from the Southampton Women's survey

(2013) Samuel A. Collins et al.   PEDIATRIC PULMONOLOGY

Daily vs. intermittent inhaled corticosteroids for recurrent wheezing and mild persistent asthma: A systematic review with meta-analysis

(2013) Gustavo J. Rodrigo et al.   RESPIRATORY MEDICINE

Severe episodic viral wheeze in preschool children: High risk of asthma at age 5–10 years

(2012) Lucie Kappelle et al.   EUROPEAN JOURNAL OF PEDIATRICS

The effect of montelukast on respiratory symptoms and lung function in wheezy infants

(2012) Anna S. Pelkonen et al.   EUROPEAN RESPIRATORY JOURNAL

Diagnosis and management of early asthma in preschool-aged children

(2012) Leonard B. Bacharier et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Assessment of Controversial Pediatric Asthma Management Options Using GRADE

(2012) N. Boluyt et al.   PEDIATRICS

Adequate Levels of Adherence with Controller Medication Is Associated with Increased Use of Rescue Medication in Asthmatic Children

(2012) Hajer Elkout et al.   PLoS One

Budesonide Inhalation Suspension Versus Montelukast in Children Aged 2 to 4 Years with Mild Persistent Asthma

(2012) Stanley J. Szefler et al.   Journal of Allergy and Clinical Immunology-In Practice

Intermittent or daily montelukast versus placebo for episodic asthma in children

(2011) Erkka Valovirta et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Clinical effectiveness of inhaled corticosteroids versus montelukast in children with asthma: prescription patterns and patient adherence as key factors

(2011) Francine M. Ducharme et al.   CURRENT MEDICAL RESEARCH AND OPINION

Phenotype-directed treatment of pre-school-aged children with recurrent wheeze

(2011) André Schultz et al.   JOURNAL OF PAEDIATRICS AND CHILD HEALTH

Daily or Intermittent Budesonide in Preschool Children with Recurrent Wheezing

(2011) Robert S. Zeiger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Wheeze in Preschool Age Is Associated with Pulmonary Bacterial Infection and Resolves after Antibiotic Therapy

(2011) Nicolaus Schwerk et al.   PLoS One

Ciclesonide in wheezy preschool children with a positive asthma predictive index or atopy

(2011) Paul L.P. Brand et al.   RESPIRATORY MEDICINE

The transient value of classifying preschool wheeze into episodic viral wheeze and multiple trigger wheeze

(2009) A Schultz et al.   ACTA PAEDIATRICA

Regularvsprn nebulized treatment in wheeze preschool children

(2009) A. Papi et al.   ALLERGY

Grading quality of evidence and strength of recommendations in clinical practice guidelines: Part 2 of 3. The GRADE approach to grading quality of evidence about diagnostic tests and strategies

(2009) J. L. Brożek et al.   ALLERGY

The role of inhaled corticosteroids and montelukast in children with mild-moderate asthma: results of a systematic review with meta-analysis

(2009) J. A. Castro-Rodriguez et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Exhaled Air and Aerosolized Droplet Dispersion During Application of a Jet Nebulizer

(2009) David S. Hui et al.   CHEST

Asthma in preschool children: the next challenge

(2009) Sejal Saglani et al.   Current Opinion in Allergy and Clinical Immunology

Viral-induced wheezing episodes in preschool children: approaches to therapy

(2009) Leonard B Bacharier   CURRENT OPINION IN PULMONARY MEDICINE

Patient characteristics associated with improved outcomes with use of an inhaled corticosteroid in preschool children at risk for asthma

(2009) Leonard B. Bacharier et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Loss of Asthma Control in Inner City Children with Asthma after Withdraw of Asthma Controller Medication

(2009) Kenny Y. C. Kwong et al.   JOURNAL OF ASTHMA

Can Montelukast Shorten Prednisolone Therapy in Children with Mild to Moderate Acute Asthma? A Randomized Controlled Trial

(2009) Suzanne Schuh et al.   JOURNAL OF PEDIATRICS

Preemptive Use of High-Dose Fluticasone for Virus-Induced Wheezing in Young Children

(2009) Francine M. Ducharme et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oral Prednisolone for Preschool Children with Acute Virus-Induced Wheezing

(2009) Jayachandran Panickar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy of Inhaled Corticosteroids in Infants and Preschoolers With Recurrent Wheezing and Asthma: A Systematic Review With Meta-analysis

(2009) J. A. Castro-Rodriguez et al.   PEDIATRICS

Inhaled corticosteroids or montelukast as the preferred primary long-term treatment for pediatric asthma?

(2008) Tuomas Jartti   EUROPEAN JOURNAL OF PEDIATRICS

Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach

(2008) P. L. P. Brand et al.   EUROPEAN RESPIRATORY JOURNAL

Episodic use of an inhaled corticosteroid or leukotriene receptor antagonist in preschool children with moderate-to-severe intermittent wheezing

(2008) Leonard B. Bacharier et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Fluticasone or montelukast for preschool children with asthma-like symptoms: Randomized controlled trial

(2008) Elisabeth M.W. Kooi et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Associations of wheezing phenotypes in the first 6 years of life with atopy, lung function and airway responsiveness in mid-childhood

(2008) J Henderson et al.   THORAX