Primary specification of blastocyst trophectoderm by scRNA-seq: New insights into embryo implantation

Integrated pseudotime analysis of human pre-implantation embryo single-cell transcriptomes reveals the dynamics of lineage specification

(2021) Dimitri Meistermann et al.   Cell Stem Cell

Human blastoids model blastocyst development and implantation

(2021) Harunobu Kagawa et al.   NATURE

The rRNA m6A methyltransferase METTL5 is involved in pluripotency and developmental programs

(2020) Valentina V. Ignatova et al.   GENES & DEVELOPMENT

Reconstituting the transcriptome and DNA methylome landscapes of human implantation

(2019) Fan Zhou et al.   NATURE

Dynamics of trophoblast differentiation in peri-implantation–stage human embryos

(2019) Rachel C. West et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatial oxidation of L-plastin downmodulates actin-based functions of tumor cells

(2019) Emre Balta et al.   Nature Communications

A developmental landscape of 3D-cultured human pre-gastrulation embryos

(2019) Lifeng Xiang et al.   NATURE

Mammalian endoreplication emerges to reveal a potential developmental timer

(2018) Alberto Gandarillas et al.   CELL DEATH AND DIFFERENTIATION

Derivation of Human Trophoblast Stem Cells

(2018) Hiroaki Okae et al.   Cell Stem Cell

Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human pre-implantation epiblast

(2018) Giuliano G. Stirparo et al.   DEVELOPMENT

EFhd2/swiprosin-1 regulates LPS-induced macrophage recruitment via enhancing actin polymerization and cell migration

(2018) Ye Tu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Regulation of human trophoblast cell syncytialization by transcription factors STAT5B and NR4A3

(2018) Kazuya Kusama et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Tracing the temporal-spatial transcriptome landscapes of the human fetal digestive tract using single-cell RNA-sequencing

(2018) Shuai Gao et al.   NATURE CELL BIOLOGY

Single-cell RNA-seq reveals the diversity of trophoblast subtypes and patterns of differentiation in the human placenta 

(2018) Yawei Liu et al.   CELL RESEARCH

Single-cell reconstruction of the early maternal–fetal interface in humans

(2018) Roser Vento-Tormo et al.   NATURE

GATA2/3-TFAP2A/C transcription factor network couples human pluripotent stem cell differentiation to trophectoderm with repression of pluripotency

(2017) Christian Krendl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression and Regulation of Retinoic Acid Receptor Responders in the Human Placenta

(2017) Hanna Huebner et al.   Reproductive Sciences

Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos

(2016) Sophie Petropoulos et al.   CELL

CD74-Downregulation of Placental Macrophage-Trophoblastic Interactions in PreeclampsiaNovelty and Significance

(2016) Lukasz Przybyl et al.   CIRCULATION RESEARCH

Stem cell insights into human trophoblast lineage differentiation

(2016) Teena KJB Gamage et al.   HUMAN REPRODUCTION UPDATE

Self-organization of the human embryo in the absence of maternal tissues

(2016) Marta N. Shahbazi et al.   NATURE CELL BIOLOGY

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

(2016) I. Tirosh et al.   SCIENCE

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Defining the three cell lineages of the human blastocyst by single-cell RNA-seq

(2015) Paul Blakeley et al.   DEVELOPMENT

Assessment of aneuploidy formation in human blastocysts resulting from donated eggs and the necessity of the embryos for aneuploidy screening

(2015) Ghassan Haddad et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Spatial reconstruction of single-cell gene expression data

(2015) Rahul Satija et al.   NATURE BIOTECHNOLOGY

Statistical significance of variables driving systematic variation in high-dimensional data

(2014) Neo Christopher Chung et al.   BIOINFORMATICS

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

The chemokine receptors ACKR2 and CCR2 reciprocally regulate lymphatic vessel density

(2014) K. M. Lee et al.   EMBO JOURNAL

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Fetal–maternal communication: the role of Notch signalling in embryo implantation

(2014) Carly Cuman et al.   REPRODUCTION

Single-cell methylome landscapes of mouse embryonic stem cells and early embryos analyzed using reduced representation bisulfite sequencing

(2013) H. Guo et al.   GENOME RESEARCH

Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells

(2013) Liying Yan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Positive Feedback Loop Involving Gcm1 and Fzd5 Directs Chorionic Branching Morphogenesis in the Placenta

(2013) Jinhua Lu et al.   PLOS BIOLOGY

FMNL2 Drives Actin-Based Protrusion and Migration Downstream of Cdc42

(2012) Jennifer Block et al.   CURRENT BIOLOGY

Human trophectoderm cells are not yet committed

(2012) C. De Paepe et al.   HUMAN REPRODUCTION

Human placentation from nidation to 5 weeks of gestation. Part I: What do we know about formative placental development following implantation?

(2012) J.L. James et al.   PLACENTA

The Translation Factor eIF6 Is a Notch-Dependent Regulator of Cell Migration and Invasion

(2012) Dario Benelli et al.   PLoS One

A new model for embryo implantation: coculture of blastocysts and Ishikawa cells

(2011) Dan Zhang et al.   GYNECOLOGICAL ENDOCRINOLOGY

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Tubulointerstitial Nephritis Antigen-Like 1 Is Expressed in the Uterus and Binds with Integrins in Decidualized Endometrium During Postimplantation in Mice1

(2009) Yumiko Tajiri et al.   BIOLOGY OF REPRODUCTION

Glial cell missing-1 transcription factor is required for the differentiation of the human trophoblast

(2009) D Baczyk et al.   CELL DEATH AND DIFFERENTIATION

Regulatory T-cells and immune tolerance in pregnancy: a new target for infertility treatment?

(2009) L. R. Guerin et al.   HUMAN REPRODUCTION UPDATE

Induction of autophagy by spermidine promotes longevity

(2009) Tobias Eisenberg et al.   NATURE CELL BIOLOGY

Expression and Function of PDCD1 at the Human Maternal-Fetal Interface1

(2008) Elizabeth S. Taglauer et al.   BIOLOGY OF REPRODUCTION

Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation

(2008) Valentina Gandin et al.   NATURE

Glial Cell Missing 1 Regulates Placental Growth Factor (PGF) Gene Transcription in Human Trophoblast1

(2007) Miao Chang et al.   BIOLOGY OF REPRODUCTION

CYP26A1 knockout embryonic stem cells exhibit reduced differentiation and growth arrest in response to retinoic acid

(2007) Simne Langton et al.   DEVELOPMENTAL BIOLOGY