Journal
FRONTIERS IN ENDOCRINOLOGY
Volume 13, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fendo.2022.890307
Keywords
organochlorine pesticides; breast milk; lactation; infant; estrogen endocrine disruptors
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Funding
- National Natural Science Foundation of China [32072722, 32072721, 81860266]
- National Transgenic Creature Breeding Grand Project [2016zx08008-003]
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This article introduces the effects of organochlorine pollutants on women's lactation ability and infant health. It emphasizes the accumulation of organochlorine contaminants in breast milk fat and their transfer to infants through breastfeeding. Additionally, the article mentions the transmission of toxic substances from the mother to the fetus through the placenta, and provides measures for controlling organochlorine pollutants.
There are many organochlorine pollutants in the environment, which can be directly or indirectly exposed to by mothers, and as estrogen endocrine disruptors can cause damage to the lactation capacity of the mammary gland. In addition, because breast milk contains a lot of nutrients, it is the most important food source for new-born babies. If mothers are exposed to organochlorine pesticides (OCPs), the lipophilic organochlorine contaminants can accumulate in breast milk fat and be passed to the infant through breast milk. Therefore, it is necessary to investigate organochlorine contaminants in human milk to estimate the health risks of these contaminants to breastfed infants. In addition, toxic substances in the mother can also be passed to the fetus through the placenta, which is also something we need to pay attention to. This article introduces several types of OCPs, such as dichlorodiphenyltrichloroethane (DDT), methoxychlor (MXC), hexachlorocyclohexane (HCH), endosulfan, chlordane, heptachlorand and hexachlorobenzene (HCB), mainly expounds their effects on women's lactation ability and infant health, and provides reference for maternal and infant health. In addition, some measures and methods for the control of organochlorine pollutants are also described here.
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