Mussel-inspired dopamine-CuII coated polyetheretherketone surface with direct and immunomodulatory effect to facilitate osteogenesis, angiogenesis, and antibacterial ability

Sponge-inspired Sulfonated Polyetheretherketone loaded with Polydopamine-protected Osthole Nanoparticles and Berberine enhances Osteogenic Activity and prevents implant-related infections

(2022) Shang Sang et al.   CHEMICAL ENGINEERING JOURNAL

Skeletal infections: microbial pathogenesis, immunity and clinical management

(2022) Elysia A. Masters et al.   NATURE REVIEWS MICROBIOLOGY

Debridement, antibiotics, and implant retention after revision arthroplasty

(2022) Karin Veerman et al.   Bone & Joint Journal

Immunomodulatory Biomaterials and Their Application in Therapies for Chronic Inflammation-Related Diseases

(2021) Jayachandra Reddy Nakkala et al.   Acta Biomaterialia

Biofunction of Polydopamine Coating in Stem Cell Culture

(2021) Zijun Deng et al.   ACS Applied Materials & Interfaces

Antimicrobial Peptides and Copper(II) Ions: Novel Therapeutic Opportunities

(2021) Jasmin Portelinha et al.   CHEMICAL REVIEWS

Use of Plasma Technologies for Antibacterial Surface Properties of Metals

(2021) Metka Benčina et al.   MOLECULES

Modification of polyetheretherketone implants: from enhancing bone integration to enabling multi-modal therapeutics

(2021) Miaomiao He et al.   Acta Biomaterialia

A practical guide for evaluating the osteoimmunomodulatory properties of biomaterials

(2021) Gemma Mestres et al.   Acta Biomaterialia

The sulfonated polyetheretherketone with 3D structure modified by two bio-inspired methods shows osteogenic and antibacterial functions

(2021) Shang Sang et al.   CHEMICAL ENGINEERING JOURNAL

Polydopamine-assisted immobilization of silk fibroin and its derived peptide on chemically oxidized titanium to enhance biological activity in vitro

(2021) Changzhen Xu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Exosome-functionalized polyetheretherketone-based implant with immunomodulatory property for enhancing osseointegration

(2021) Lei Fan et al.   Bioactive Materials

Dual-functional polyetheretherketone surface modification for regulating immunity and bone metabolism

(2021) Shicheng Huo et al.   CHEMICAL ENGINEERING JOURNAL

Surgical site infection prevention through bundled interventions in hip replacement surgery: A systematic review

(2021) Costanza Vicentini et al.   International Journal of Surgery

Fabrication of physical and chemical crosslinked hydrogels for bone tissue engineering

(2021) Xu Xue et al.   Bioactive Materials

pH-responsive silk fibroin-based CuO/Ag micro/nano coating endows polyetheretherketone with synergistic antibacterial ability, osteogenesis, and angiogenesis

(2020) Jianglong Yan et al.   Acta Biomaterialia

Biological properties of copper-doped biomaterials for orthopedic applications: A review of antibacterial, angiogenic and osteogenic aspects

(2020) Aurélie Jacobs et al.   Acta Biomaterialia

Combating Implant Infections: Shifting Focus from Bacteria to Host

(2020) Saber Amin Yavari et al.   ADVANCED MATERIALS

Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion

(2020) Florida Voli et al.   CANCER RESEARCH

Graphdiyne-modified TiO2 nanofibers with osteoinductive and enhanced photocatalytic antibacterial activities to prevent implant infection

(2020) Rui Wang et al.   Nature Communications

Synergistic effects of immunoregulation and osteoinduction of ds-block elements on titanium surface

(2020) Lan Chen et al.   Bioactive Materials

Osteogenesis, angiogenesis and immune response of Mg-Al layered double hydroxide coating on pure Mg

(2020) Shi Cheng et al.   Bioactive Materials

A surface-engineered polyetheretherketone biomaterial implant with direct and immunoregulatory antibacterial activity against methicillin-resistant Staphylococcus aureus

(2019) Wei Liu et al.   BIOMATERIALS

Concentration-dependent osteogenic and angiogenic biological performances of calcium phosphate cement modified with copper ions

(2019) Jing Zhang et al.   Materials Science & Engineering C-Materials for Biological Applications

Activating Macrophages for Enhanced Osteogenic and Bactericidal performance by Cu Ion Release from Micro/Nano-Topographical Coating on Titanium Substrate

(2019) Qianli Huang et al.   Acta Biomaterialia

Triple-functional polyetheretherketone surface with enhanced bacteriostasis and anti-inflammatory and osseointegrative properties for implant application

(2019) Xiao Xu et al.   BIOMATERIALS

Revision Risk for Total Knee Arthroplasty Converted from Medial Unicompartmental Knee Arthroplasty

(2019) Anders El-Galaly et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Dose-response relationships between copper and its biocompatibility/antibacterial activities

(2019) Kunqiang Li et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Exosome‐Guided Phenotypic Switch of M1 to M2 Macrophages for Cutaneous Wound Healing

(2019) Hyosuk Kim et al.   Advanced Science

Surface Modification Strategies to Improve the Osseointegration of Poly(etheretherketone) and Its Composites

(2019) Emily Buck et al.   MACROMOLECULAR BIOSCIENCE

Tuning the surface immunomodulatory functions of polyetheretherketone for enhanced osseointegration

(2019) Ang Gao et al.   BIOMATERIALS

A multifaceted coating on titanium dictates osteoimmunomodulation and osteo/angio-genesis towards ameliorative osseointegration

(2018) Long Bai et al.   BIOMATERIALS

Macrophage phenotype switch by sequential action of immunomodulatory cytokines from hydrogel layers on titania nanotubes

(2018) Junhong Chen et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

The Cu-containing TiO 2 coatings with modulatory effects on macrophage polarization and bactericidal capacity prepared by micro-arc oxidation on titanium substrates

(2018) Qianli Huang et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Implant infections: adhesion, biofilm formation and immune evasion

(2018) Carla Renata Arciola et al.   NATURE REVIEWS MICROBIOLOGY

Preparation of Micro/Nano-Structure Copper-Substituted Hydroxyapatite Scaffolds with Improved Angiogenesis Capacity for Bone Regeneration

(2018) Adil Elrayah et al.   Materials

Assembly of Metal–Phenolic/Catecholamine Networks for Synergistically Anti-Inflammatory, Antimicrobial, and Anticoagulant Coatings

(2018) Xiangyang Li et al.   ACS Applied Materials & Interfaces

Knee replacement

(2018) Andrew J Price et al.   LANCET

Current Advances in Immunomodulatory Biomaterials for Bone Regeneration

(2018) Jinkyu Lee et al.   Advanced Healthcare Materials

Mussel-inspired dopamine-CuII coatings for sustained in situ generation of nitric oxide for prevention of stent thrombosis and restenosis

(2018) Feng Zhang et al.   BIOMATERIALS

Pro-inflammatory M1 macrophages promote Osteogenesis by mesenchymal stem cells via the COX-2-prostaglandin E2 pathway

(2017) Laura Y. Lu et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Staphylococcal Biofilms and Immune Polarization During Prosthetic Joint Infection

(2017) Casey M. Gries et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

Integrin-Mediated Interactions Control Macrophage Polarization in 3D Hydrogels

(2017) Byung-Hyun Cha et al.   Advanced Healthcare Materials

OsteoMacs: Key players around bone biomaterials

(2016) Richard J. Miron et al.   BIOMATERIALS

How Mammalian Cells Acquire Copper: An Essential but Potentially Toxic Metal

(2016) Jack H. Kaplan et al.   BIOPHYSICAL JOURNAL

Polyetheretherketone (PEEK) for medical applications

(2016) Ivan Vladislavov Panayotov et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

New WHO recommendations on intraoperative and postoperative measures for surgical site infection prevention: an evidence-based global perspective

(2016) Benedetta Allegranzi et al.   LANCET INFECTIOUS DISEASES

Effect of copper-doped silicate 13–93 bioactive glass scaffolds on the response of MC3T3-E1 cells in vitro and on bone regeneration and angiogenesis in rat calvarial defects in vivo

(2016) Yinan Lin et al.   Materials Science & Engineering C-Materials for Biological Applications

Copper Exposure Perturbs Brain Inflammatory Responses and Impairs Clearance of Amyloid-Beta

(2016) Masashi Kitazawa et al.   TOXICOLOGICAL SCIENCES

Sequential delivery of immunomodulatory cytokines to facilitate the M1-to-M2 transition of macrophages and enhance vascularization of bone scaffolds

(2015) Kara L. Spiller et al.   BIOMATERIALS

Concentration Ranges of Antibacterial Cations for Showing the Highest Antibacterial Efficacy but the Least Cytotoxicity against Mammalian Cells: Implications for a New Antibacterial Mechanism

(2015) Chengyun Ning et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The Pathology of Orthopedic Implant Failure Is Mediated by Innate Immune System Cytokines

(2014) Stefan Landgraeber et al.   MEDIATORS OF INFLAMMATION

Targeting Macrophage Activation for the Prevention and Treatment of Staphylococcus aureus Biofilm Infections

(2013) M. L. Hanke et al.   JOURNAL OF IMMUNOLOGY

Copper-containing mesoporous bioactive glass scaffolds with multifunctional properties of angiogenesis capacity, osteostimulation and antibacterial activity

(2012) Chengtie Wu et al.   BIOMATERIALS

A Large Multicenter Study of Methicillin–Susceptible and Methicillin–Resistant Staphylococcus aureus Prosthetic Joint Infections Managed With Implant Retention

(2012) Jaime Lora-Tamayo et al.   CLINICAL INFECTIOUS DISEASES

Infections and immunodeficiency in Down syndrome

(2011) G. Ram et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Metallic Copper as an Antimicrobial Surface

(2010) Gregor Grass et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Microbial biofilm growth vs. tissue integration: “The race for the surface” experimentally studied

(2009) Guruprakash Subbiahdoss et al.   Acta Biomaterialia