Integrated Serum Pharmacochemistry, Metabolomics, and Network Pharmacology to Reveal the Material Basis and Mechanism of Danggui Shaoyao San in the Treatment of Primary Dysmenorrhea

High‐throughput UPLC‐Q‐TOF‐MS/MS coupled with multivariable data processing approach for the rapid screening and characterization of chemical constituents and potential bioactive compounds from Danggui Shaoyao San

(2022) Na Li et al.   BIOMEDICAL CHROMATOGRAPHY

Effective Material Basis and Mechanism Analysis of Compound Banmao Capsule against Tumors Using Integrative Network Pharmacology and Molecular Docking

(2021) Tian-Mu He et al.   Evidence-based Complementary and Alternative Medicine

Studies on the compatibility mechanism and material basis of Danggui Buxue Decoction against anemia mice using metabonomics and network pharmacology

(2021) YueTao Liu et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Urocortins exhibit differential effects on PGE2 and PGF2α output via CRHR2 in human myometrium

(2021) Xingji You et al.   REPRODUCTION

Comprehensive investigation of pharmacodyamic material basis of Wikstroemia indica (L.) C. A. Mey. by serum pharmacochemistry and bivariate correlation analysis

(2021) Jiayue Wang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Study on the Mechanism of the Danggui–Chuanxiong Herb Pair on Treating Thrombus through Network Pharmacology and Zebrafish Models

(2021) Mengqi Zhang et al.   ACS Omega

Systems pharmacological study based on UHPLC-Q-Orbitrap-HRMS, network pharmacology and experimental validation to explore the potential mechanisms of Danggui-Shaoyao-San against atherosclerosis

(2021) Yiming Bi et al.   JOURNAL OF ETHNOPHARMACOLOGY

Network pharmacology: curing causal mechanisms instead of treating symptoms

(2021) Cristian Nogales et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Comparison of effect of auriculotherapy and mefenamic acid on the severity and systemic symptoms of primary dysmenorrhea: a randomized clinical trial

(2021) Masoomeh Vahedi et al.   Trials

Prevalence, risk factors, and management practices of primary dysmenorrhea among young females

(2021) Samar Karout et al.   BMC Womens Health

Metabolomics study of Angelica sinensis (Oliv.) Diels on the abnormal uterine bleeding rats by ultra‐performance liquid chromatography–quadrupole–time‐of‐flight mass spectrometry analysis

(2021) Ting‐Ting Chen et al.   Food Science & Nutrition

Long‐term use of dienogest for the treatment of primary and secondary dysmenorrhea

(2020) Yutaka Osuga et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Prevalence of primary dysmenorrhea, its intensity, impact and associated factors among female students’ at Gondar town preparatory school, Northwest Ethiopia

(2020) Abere Woretaw Azagew et al.   BMC Womens Health

Network Pharmacology-Based Prediction and Verification of the Active Ingredients and Potential Targets of Zuojinwan for Treating Colorectal Cancer

(2020) Siqi Huang et al.   Drug Design Development and Therapy

Effect of traditional Chinese medicine formula GeGen decoction on primary dysmenorrhea: A randomized controlled trial study

(2020) Chengzhi Chai et al.   JOURNAL OF ETHNOPHARMACOLOGY

PERSISTENT METABOLOMIC ALTERATIONS CHARACTERIZE CHRONIC CRITICAL ILLNESS AFTER SEVERE TRAUMA

(2020) Dara L. Horn et al.   Journal of Trauma and Acute Care Surgery

PGE2 vs PGF2α in human parturition

(2020) Wen-jiao Li et al.   PLACENTA

Traditional Chinese Medicine Network Pharmacology in Cardiovascular Precision Medicine

(2020) Li Gao et al.   CURRENT PHARMACEUTICAL DESIGN

Chlorinated insecticides (toxaphene and endrin) affect oxytocin, testosterone, oestradiol and prostaglandin secretion from ovarian and uterine cells as well as myometrial contractions in cow in vitro

(2018) Michael Hubert Wrobel et al.   CHEMOSPHERE

Dose-response characteristics of Clematis triterpenoid saponins and clematichinenoside AR in rheumatoid arthritis rats by liquid chromatography/mass spectrometry-based serum and urine metabolomics

(2017) Rui Li et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Metabolomics study on primary dysmenorrhea patients during the luteal regression stage based on ultra performance liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry

(2017) Ling Fang et al.   Molecular Medicine Reports

Neuroprotective effects of Danggui-Jakyak-San on rat stroke model through antioxidant/antiapoptotic pathway

(2016) Sang-Ho Kim et al.   JOURNAL OF ETHNOPHARMACOLOGY

Viburnum opulus L.: A remedy for the treatment of endometriosis demonstrated by rat model of surgically-induced endometriosis

(2016) Gülçin Saltan et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effects and mechanisms of Shaofu-Zhuyu decoction and its major bioactive component for Cold - Stagnation and Blood – Stasis primary dysmenorrhea rats

(2016) Xiaochen Huang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Untargeted Metabolomics Strategies—Challenges and Emerging Directions

(2016) Alexandra C. Schrimpe-Rutledge et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Herbal medicine (Danggui Shaoyao San) for treating primary dysmenorrhea: A systematic review and meta-analysis of randomized controlled trials

(2016) Hye Won Lee et al.   MATURITAS

Drug target identification using network analysis: Taking active components in Sini decoction as an example

(2016) Si Chen et al.   Scientific Reports

Analgesic Effects of Danggui-Shaoyao-San on Various “Phenotypes” of Nociception and Inflammation in a Formalin Pain Model

(2015) Jun-Bin Yin et al.   MOLECULAR NEUROBIOLOGY

Beneficial effect of Danggui-Shaoyao-San, a traditional Chinese medicine, on drowsiness induced by chronic restraint stress

(2015) Kecheng Zhou et al.   NEUROSCIENCE LETTERS

Hippocampal metabolomics using ultrahigh-resolution mass spectrometry reveals neuroinflammation from Alzheimer’s disease in CRND8 mice

(2013) Shuhai Lin et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Non-steroidal anti-inflammatory drug modulates oxidative stress and calcium ion levels in the neutrophils of patients with primary dysmenorrhea

(2013) Önder Kaplan et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Prostaglandin E2 contributes to the synthesis of brain-derived neurotrophic factor in primary sensory neuron in ganglion explant cultures and in a neuropathic pain model

(2012) Pedro Cruz Duarte et al.   EXPERIMENTAL NEUROLOGY

The role of the oxidative-stress in the endometriosis-related infertility

(2009) Areti Augoulea et al.   GYNECOLOGICAL ENDOCRINOLOGY

Danggui-Shaoyao-San, a traditional Chinese prescription, suppresses PGF2α production in endometrial epithelial cells by inhibiting COX-2 expression and activity

(2008) Y.Q. Hua et al.   PHYTOMEDICINE