S100A10 and its binding partners in depression and antidepressant actions

Molecular and Cellular Adaptations in Hippocampal Parvalbumin Neurons Mediate Behavioral Responses to Chronic Social Stress

(2022) Dionnet L. Bhatti et al.   Frontiers in Molecular Neuroscience

Serotonin receptor 4 in the hippocampus modulates mood and anxiety

(2021) Remzi Karayol et al.   MOLECULAR PSYCHIATRY

5-HT4 Receptors Are Not Involved in the Effects of Fluoxetine in the Corticosterone Model of Depression

(2021) Josep Amigo et al.   ACS Chemical Neuroscience

Identification of Neurensin-2 as a novel modulator of emotional behavior

(2021) Gali Umschweif et al.   MOLECULAR PSYCHIATRY

Activation of the p11/SMARCA3/Neurensin-2 pathway in parvalbumin interneurons mediates the response to chronic antidepressants

(2021) Gali Umschweif et al.   MOLECULAR PSYCHIATRY

Glutamate and GABA Homeostasis and Neurometabolism in Major Depressive Disorder

(2021) Ajay Sarawagi et al.   Frontiers in Psychiatry

A national survey on depressive and anxiety disorders in Afghanistan: A highly traumatized population

(2021) V. Kovess-Masfety et al.   BMC Psychiatry

Ependymal cells-CSF flow regulates stress-induced depression

(2021) Ji-Seon Seo et al.   MOLECULAR PSYCHIATRY

Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic

(2021) Damian F Santomauro et al.   LANCET

Reduced Kv3.1 Activity in Dentate Gyrus Parvalbumin Cells Induces Vulnerability to Depression.

(2020) Lucian Medrihan et al.   BIOLOGICAL PSYCHIATRY

AP-1 controls the p11-dependent antidepressant response

(2020) Revathy U. Chottekalapanda et al.   MOLECULAR PSYCHIATRY

Translating the promise of 5HT4 receptor agonists for the treatment of depression

(2020) Susannah E Murphy et al.   PSYCHOLOGICAL MEDICINE

Modulation of Ion Channels and Receptors by p11 (S100A10)

(2020) Ji-Seon Seo et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Nonspecific Expression in Limited Excitatory Cell Populations in Interneuron-Targeting Cre-driver Lines Can Have Large Functional Effects

(2020) Daniel Müller-Komorowska et al.   Frontiers in Neural Circuits

Chemotherapy-induced S100A10 recruits KDM6A to facilitate OCT4-mediated breast cancer stemness

(2020) Haiquan Lu et al.   JOURNAL OF CLINICAL INVESTIGATION

P11 deficiency increases stress reactivity along with HPA axis and autonomic hyperresponsiveness

(2020) Vasco C. Sousa et al.   MOLECULAR PSYCHIATRY

Inhibition of GABA interneurons in the mPFC is sufficient and necessary for rapid antidepressant responses

(2020) Manoela V. Fogaça et al.   MOLECULAR PSYCHIATRY

Prevalence of Depression Symptoms in US Adults Before and During the COVID-19 Pandemic

(2020) Catherine K. Ettman et al.   JAMA Network Open

S100A10 Has a Critical Regulatory Function in Mammary Tumor Growth and Metastasis: Insights Using MMTV-PyMT Oncomice and Clinical Patient Sample Analysis

(2020) Alamelu G. Bharadwaj et al.   Cancers

HCN2 Channels in Cholinergic Interneurons of Nucleus Accumbens Shell Regulate Depressive Behaviors

(2019) Jia Cheng et al.   NEURON

Hippocampal mossy cell involvement in behavioral and neurogenic responses to chronic antidepressant treatment

(2019) Seo-Jin Oh et al.   MOLECULAR PSYCHIATRY

Emergence of 5-HT5A signaling in parvalbumin neurons mediates delayed antidepressant action

(2019) Yotam Sagi et al.   MOLECULAR PSYCHIATRY

Ahnak scaffolds p11/Anxa2 complex and L-type voltage-gated calcium channel and modulates depressive behavior

(2019) Junghee Jin et al.   MOLECULAR PSYCHIATRY

Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments

(2019) Ronald S. Duman et al.   NEURON

Esketamine for Treatment-Resistant Depression — First FDA-Approved Antidepressant in a New Class

(2019) Jean Kim et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mapping the physiological and molecular markers of stress and SSRI antidepressant treatment in S100a10 corticostriatal neurons

(2019) Derya Sargin et al.   MOLECULAR PSYCHIATRY

Organization and regulation of gene transcription

(2019) Patrick Cramer   NATURE

GABA interneurons are the cellular trigger for ketamine’s rapid antidepressant actions

(2019) Danielle M. Gerhard et al.   JOURNAL OF CLINICAL INVESTIGATION

Adrenal serotonin derives from accumulation by the antidepressant-sensitive serotonin transporter

(2018) Rebecca L. Brindley et al.   PHARMACOLOGICAL RESEARCH

The 5-HT1B receptor - a potential target for antidepressant treatment

(2018) Mikael Tiger et al.   PSYCHOPHARMACOLOGY

P11 promoter methylation predicts the antidepressant effect of electroconvulsive therapy

(2018) Alexandra Neyazi et al.   Translational Psychiatry

S100A10 and Cancer Hallmarks: Structure, Functions, and its Emerging Role in Ovarian Cancer

(2018) Tannith Noye et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Social stress induces neurovascular pathology promoting depression

(2017) Caroline Menard et al.   NATURE NEUROSCIENCE

Initiation of Behavioral Response to Antidepressants by Cholecystokinin Neurons of the Dentate Gyrus

(2017) Lucian Medrihan et al.   NEURON

Alterations of p11 in brain tissue and peripheral blood leukocytes in Parkinson’s disease

(2017) Holly Green et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prevalence of depression in Syrian refugees and the influence of religiosity

(2016) Wadih J. Naja et al.   COMPREHENSIVE PSYCHIATRY

A REVIEW OF KETAMINE ABUSE AND DIVERSION

(2016) Sean Sassano-Higgins et al.   DEPRESSION AND ANXIETY

Cell- and region-specific expression of depression-related protein p11 (S100a10) in the brain

(2016) Ana Milosevic et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Cellular and molecular basis for stress-induced depression

(2016) J-S Seo et al.   MOLECULAR PSYCHIATRY

A Lack of Serotonin 1B Autoreceptors Results in Decreased Anxiety and Depression-Related Behaviors

(2016) Katherine M Nautiyal et al.   NEUROPSYCHOPHARMACOLOGY

Opposing roles for serotonin in cholinergic neurons of the ventral and dorsal striatum

(2016) Michael S. Virk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p11 modulates L-DOPA therapeutic effects and dyskinesia via distinct cell types in experimental Parkinsonism

(2016) Nicoletta Schintu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene therapy blockade of dorsal striatal p11 improves motor function and dyskinesia in parkinsonian mice

(2016) Roberta Marongiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Knockout ofp11attenuates the acquisition and reinstatement of cocaine conditioned place preference in male but not in female mice

(2016) Panayotis K. Thanos et al.   SYNAPSE

Role of hippocampal p11 in the sustained antidepressant effect of ketamine in the chronic unpredictable mild stress model

(2016) H-L Sun et al.   Translational Psychiatry

Major depressive disorder

(2016) Christian Otte et al.   Nature Reviews Disease Primers

CACNA1D De Novo Mutations in Autism Spectrum Disorders Activate Cav1.3 L-Type Calcium Channels

(2015) Alexandra Pinggera et al.   BIOLOGICAL PSYCHIATRY

Alteration by p11 of mGluR5 localization regulates depression-like behaviors

(2015) K-W Lee et al.   MOLECULAR PSYCHIATRY

Cell-Type Specific Expression of p11 Controls Cocaine Reward

(2014) Margarita Arango-Lievano et al.   BIOLOGICAL PSYCHIATRY

Cooperative Binding of Annexin A2 to Cholesterol- and Phosphatidylinositol-4,5-Bisphosphate-Containing Bilayers

(2014) Patrick Drücker et al.   BIOPHYSICAL JOURNAL

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Ahnak functions as a tumor suppressor via modulation of TGFβ/Smad signaling pathway

(2014) I H Lee et al.   ONCOGENE

Is the mGlu5 receptor a possible target for new antidepressant drugs?

(2014) Agnieszka Pałucha-Poniewiera et al.   Pharmacological Reports

SMARCA3, a Chromatin-Remodeling Factor, Is Required for p11-Dependent Antidepressant Action

(2013) Yong-Seok Oh et al.   CELL

Spt6

(2013) Hiroaki Kato et al.   Epigenetics

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

(2013)   LANCET

p11 and its role in depression and therapeutic responses to antidepressants

(2013) Per Svenningsson et al.   NATURE REVIEWS NEUROSCIENCE

Structure of a C-terminal AHNAK peptide in a 1:2:2 complex with S100A10 and an acetylated N-terminal peptide of annexin A2

(2012) Gabriel Ozorowski et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Identification of the Cortical Neurons that Mediate Antidepressant Responses

(2012) Eric F. Schmidt et al.   CELL

Functions of S100 Proteins

(2012) R. Donato et al.   CURRENT MOLECULAR MEDICINE

The Annexin A2/S100A10 System in Health and Disease: Emerging Paradigms

(2012) Nadia Hedhli et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Cognitive impairment in major depression and the mGlu2 receptor as a therapeutic target

(2012) Celia Goeldner et al.   NEUROPHARMACOLOGY

mGlu2/3 and mGlu5 receptors: Potential targets for novel antidepressants

(2012) Shigeyuki Chaki et al.   NEUROPHARMACOLOGY

Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior

(2012) J. L. Warner-Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CACNA1C (Cav1.2) in the pathophysiology of psychiatric disease

(2012) Shambhu Bhat et al.   PROGRESS IN NEUROBIOLOGY

Antidepressant treatment is associated with epigenetic alterations in the promoter of P11 in a genetic model of depression

(2011) Philippe A. Melas et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

The S100A10-Annexin A2 Complex Provides a Novel Asymmetric Platform for Membrane Repair

(2011) Atoosa Rezvanpour et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Co-expression of serotonin 5-HT1B and 5-HT4 receptors in p11 containing cells in cerebral cortex, hippocampus, caudate-putamen and cerebellum

(2011) Martin Egeland et al.   NEUROPHARMACOLOGY

Towards a glutamate hypothesis of depression

(2011) Gerard Sanacora et al.   NEUROPHARMACOLOGY

Neurogenic Effects of Fluoxetine Are Attenuated in p11 (S100A10) Knockout Mice

(2010) Martin Egeland et al.   BIOLOGICAL PSYCHIATRY

A Role for p11 in the Antidepressant Action of Brain-Derived Neurotrophic Factor

(2010) Jennifer L. Warner-Schmidt et al.   BIOLOGICAL PSYCHIATRY

Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder

(2010) Y Liu et al.   MOLECULAR PSYCHIATRY

Reversal of Depressed Behaviors in Mice by p11 Gene Therapy in the Nucleus Accumbens

(2010) B. Alexander et al.   Science Translational Medicine

Differential Metabotropic Glutamate Receptor Expression and Modulation in Two Neocortical Inhibitory Networks

(2009) Qian-Quan Sun et al.   JOURNAL OF NEUROPHYSIOLOGY

Role of p11 in Cellular and Behavioral Effects of 5-HT4 Receptor Stimulation

(2009) J. L. Warner-Schmidt et al.   JOURNAL OF NEUROSCIENCE

The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia

(2009) E K Green et al.   MOLECULAR PSYCHIATRY

Requirement for AHNAK1-mediated calcium signaling during T lymphocyte cytolysis

(2009) D. Matza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Annexin A2 at the interface between F-actin and membranes enriched in phosphatidylinositol 4,5,-bisphosphate

(2008) Matthew J. Hayes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A Scaffold Protein, AHNAK1, Is Required for Calcium Signaling during T Cell Activation

(2008) Didi Matza et al.   IMMUNITY

Evidence for a role of the 5-HT1B receptor and its adaptor protein, p11, in L-DOPA treatment of an animal model of Parkinsonism

(2008) X. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sucrose intake and fasting glucose levels in 5-HT1A and 5-HT1B receptor mutant mice

(2007) Anita J. Bechtholt et al.   PHYSIOLOGY & BEHAVIOR