Journal
JOURNAL OF ENDOCRINOLOGY
Volume 231, Issue 3, Pages R101-R119Publisher
BIOSCIENTIFICA LTD
DOI: 10.1530/JOE-16-0157
Keywords
inflammatory diseases; labour; cytokines; reproduction
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Funding
- MRC [G0501957]
- Westminster Medical School Research Trust
- St Stephen's AIDS Trust
- Action Medical Research and Borne, a sub-charity of CW+
- Imperial NIHR Biomedical Research Centre
- Medical Research Council [G0501957] Funding Source: researchfish
- MRC [G0501957] Funding Source: UKRI
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Human labour is an inflammatory event, physiologically driven by an interaction between hormonal and mechanical factors and pathologically associated with infection, bleeding and excessive uterine stretch. The initiation and communicators of inflammation is still not completely understood; however, a key role for cytokines has been implicated. We summarise the current understanding of the nature and role of cytokines, chemokines and hormones and their involvement in signalling within the myometrium particularly during labour.
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