Anti-Diabetic Effects of Cucurbitacins from Ibervillea lindheimeri on Induced Mouse Diabetes

A Citrullus colocynthis fruit extract acutely enhances insulin-induced GLUT4 translocation and glucose uptake in adipocytes by increasing PKB phosphorylation

(2021) Farah Drissi et al.   JOURNAL OF ETHNOPHARMACOLOGY

MGL1 Receptor Plays a Key Role in the Control of T. cruzi Infection by Increasing Macrophage Activation through Modulation of ERK1/2, c-Jun, NF-κB and NLRP3 Pathways

(2020) Tonathiu Rodriguez et al.   Cells

Natural products: Regulating glucose metabolism and improving insulin resistance

(2020) Fatma S.A. Saadeldeen et al.   Food Science and Human Wellness

Pharmacokinetics of cucurbitacin B from Trichosanthes cucumerina L. in rats

(2019) Natthaphon Hunsakunachai et al.   BMC Complementary and Alternative Medicine

AMPK: Sensing Glucose as well as Cellular Energy Status

(2018) Sheng-Cai Lin et al.   Cell Metabolism

Cucurbitane Triterpenoids from the Fruits of Momordica Charantia Improve Insulin Sensitivity and Glucose Homeostasis in Streptozotocin-Induced Diabetic Mice

(2018) Joo-Hui Han et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Cucurbitacin B Induces Hypoglycemic Effect in Diabetic Mice by Regulation of AMP-Activated Protein Kinase Alpha and Glucagon-Like Peptide-1 via Bitter Taste Receptor Signaling

(2018) Kang-Hoon Kim et al.   Frontiers in Pharmacology

Structure and Physiological Regulation of AMPK

(2018) Yan Yan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Deconvoluting AMP-activated protein kinase (AMPK) adenine nucleotide binding and sensing

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ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway

(2017) Yang Zhao et al.   Molecular Cancer

Combretum lanceolatumflowers ethanol extract inhibits hepatic gluconeogenesis: anin vivomechanism study

(2016) Juliany Torres Siqueira et al.   PHARMACEUTICAL BIOLOGY

Chemical constituents from Ibervillea lindheimeri (A. Gray) Greene

(2014) J.L. Figueroa-Hernández et al.   BIOCHEMICAL SYSTEMATICS AND ECOLOGY

Metformin: From Mechanisms of Action to Therapies

(2014) Marc Foretz et al.   Cell Metabolism

Ibervillea sonorae (Cucurbitaceae) induces the glucose uptake in human adipocytes by activating a PI3K-independent pathway

(2014) Rocio Zapata-Bustos et al.   JOURNAL OF ETHNOPHARMACOLOGY

Coordinated regulation of AMPK activity by multiple elements in the α-subunit

(2013) Feng-Jiao Xin et al.   CELL RESEARCH

Bitter Bottle Gourd (Lagenaria siceraria) Toxicity

(2013) Cynthia H. Ho et al.   JOURNAL OF EMERGENCY MEDICINE

Activation of AMPK by Bitter Melon Triterpenoids Involves CaMKKβ

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Cucurbitacins as Inducers of Cell Death and a Rich Source of Potential Anticancer Compounds

(2012)   CURRENT PHARMACEUTICAL DESIGN

Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

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Regulation of glucose transport by insulin: traffic control of GLUT4

(2012) Dara Leto et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Suppression of AMPK Activation via S485 Phosphorylation by IGF-I during Hyperglycemia Is Mediated by AKT Activation in Vascular Smooth Muscle Cells

(2011) Junyu Ning et al.   ENDOCRINOLOGY

Antiobesity and Hypoglycaemic Effects of Aqueous Extract ofIbervillea sonoraein Mice Fed a High-Fat Diet with Fructose

(2011) Fabiola Rivera-Ramírez et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Stability of cucurbitacin E in human plasma: chemical hydrolysis and role of plasma esterases

(2009) Myriam Saade et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Inhibitor hijacking of Akt activation

(2009) Tatsuya Okuzumi et al.   Nature Chemical Biology

Antidiabetic Activities of Triterpenoids Isolated from Bitter Melon Associated with Activation of the AMPK Pathway

(2008) Min-Jia Tan et al.   CHEMISTRY & BIOLOGY

AMPK: a metabolic gauge regulating whole-body energy homeostasis

(2008) Ricardo Lage et al.   TRENDS IN MOLECULAR MEDICINE