Explainable deep transfer learning model for disease risk prediction using high-dimensional genomic data

Multikernel linear mixed model with adaptive lasso for complex phenotype prediction

(2020) Yalu Wen et al.   STATISTICS IN MEDICINE

Accurate and Scalable Construction of Polygenic Scores in Large Biobank Data Sets

(2020) Sheng Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Robust inference with knockoffs

(2020) Rina Foygel Barber et al.   ANNALS OF STATISTICS

Relaxing the assumptions of knockoffs by conditioning

(2020) Dongming Huang et al.   ANNALS OF STATISTICS

A Bayesian linear mixed model for prediction of complex traits

(2020) Yang Hai et al.   BIOINFORMATICS

LDpred2: better, faster, stronger

(2020) Florian Privé et al.   BIOINFORMATICS

Deep-gKnock: Nonlinear group-feature selection with deep neural networks

(2020) Guangyu Zhu et al.   NEURAL NETWORKS

ACAT: A Fast and Powerful p Value Combination Method for Rare-Variant Analysis in Sequencing Studies

(2019) Yaowu Liu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Deep learning: new computational modelling techniques for genomics

(2019) Gökcen Eraslan et al.   NATURE REVIEWS GENETICS

Block HSIC Lasso: model-free biomarker detection for ultra-high dimensional data

(2019) Héctor Climente-González et al.   BIOINFORMATICS

Deep Knockoffs

(2019) Yaniv Romano et al.   JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

Panning for gold: ‘model-X’ knockoffs for high dimensional controlled variable selection

(2018) Emmanuel Candès et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Genetic risk prediction using a spatial autoregressive model with adaptive lasso

(2018) Yalu Wen et al.   STATISTICS IN MEDICINE

A primer on deep learning in genomics

(2018) James Zou et al.   NATURE GENETICS

Missing heritability: is the gap closing? An analysis of 32 complex traits in the Lifelines Cohort Study

(2017) Ilja M Nolte et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Polygenic scores via penalized regression on summary statistics

(2017) Timothy Shin Heng Mak et al.   GENETIC EPIDEMIOLOGY

Will Big Data Close the Missing Heritability Gap?

(2017) Hwasoon Kim et al.   GENETICS

Statistical contributions to bioinformatics: Design, modelling, structure learning and integration

(2017) Jeffrey S. Morris et al.   STATISTICAL MODELLING

Non-parametric genetic prediction of complex traits with latent Dirichlet process regression models

(2017) Ping Zeng et al.   Nature Communications

Will Big Data Close the Missing Heritability Gap?

(2017) Hwasoon Kim et al.   GENETICS

Association Analysis of Polymorphisms in TOMM40, CR1, PVRL2, SORL1, PICALM, and 14q32.13 Regions in Colombian Alzheimer Disease Patients

(2016) Jenny Ortega-Rojas et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Polygenic Epidemiology

(2016) Frank Dudbridge   GENETIC EPIDEMIOLOGY

Multikernel linear mixed models for complex phenotype prediction

(2016) Omer Weissbrod et al.   GENOME RESEARCH

The TOMM40 gene rs2075650 polymorphism contributes to Alzheimer’s disease in Caucasian, and Asian populations

(2016) Hao Huang et al.   NEUROSCIENCE LETTERS

Controlling the false discovery rate via knockoffs

(2015) Rina Foygel Barber et al.   ANNALS OF STATISTICS

The Precision Medicine Initiative

(2015) Euan A. Ashley   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

MultiBLUP: improved SNP-based prediction for complex traits

(2014) Doug Speed et al.   GENOME RESEARCH

Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

(2014) Philip L De Jager et al.   NATURE NEUROSCIENCE

APOE and APOC1 gene polymorphisms are associated with cognitive impairment progression in Chinese patients with late-onset Alzheimer′s disease

(2014) Wandong Zhang et al.   Neural Regeneration Research

Association between APOC1 Polymorphism and Alzheimer’s Disease: A Case-Control Study and Meta-Analysis

(2014) Qin Zhou et al.   PLoS One

Polygenic Modeling with Bayesian Sparse Linear Mixed Models

(2013) Xiang Zhou et al.   PLoS Genetics

Optimal Unified Approach for Rare-Variant Association Testing with Application to Small-Sample Case-Control Whole-Exome Sequencing Studies

(2012) Seunggeun Lee et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Optimal tests for rare variant effects in sequencing association studies

(2012) S. Lee et al.   BIOSTATISTICS

Differential effect of APOE genotype on amyloid load and glucose metabolism in AD dementia

(2012) R. Ossenkoppele et al.   NEUROLOGY

Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans

(2010) Andrew J. Saykin et al.   Alzheimers & Dementia

An Inherited Variable Poly-T Repeat Genotype in TOMM40 in Alzheimer Disease

(2010) Allen D. Roses   ARCHIVES OF NEUROLOGY

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

(2009) Shaun M. Purcell et al.   NATURE

A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease

(2009) A D Roses et al.   PHARMACOGENOMICS JOURNAL

Sure independence screening for ultrahigh dimensional feature space

(2008) Jianqing Fan et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY