Article
Multidisciplinary Sciences
Keren Doenyas-Barak, Merav Catalogna, Ilan Kutz, Gabriela Levi, Amir Hadanny, Sigal Tal, Shir Daphna-Tekoha, Efrat Sasson, Yarden Shechter, Shai Efrati
Summary: This study evaluated the effects of hyperbaric oxygen therapy (HBOT) on veterans with treatment resistant post-traumatic stress disorder (PTSD). The results showed that HBOT improved symptoms, brain microstructure, and functionality in these patients.
Article
Multidisciplinary Sciences
Amir Hadanny, Merav Catalogna, Slava Yaniv, Orit Stolar, Lynn Rothstein, Adi Shabi, Gil Suzin, Efrat Sasson, Erez Lang, Shachar Finci, Nir Polak, Gregory Fishlev, Ruth Tock Harpaz, Moran Adler, Ron-El Goldman, Yonatan Zemel, Yair Bechor, Shai Efrati
Summary: This study found that hyperbaric oxygen therapy (HBOT) significantly improves cognitive and behavioral function, reduces PPCS symptoms, and enhances the quality of life in pediatric patients with persistent post-concussion syndrome (PPCS), even years after the injury.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Mayssam Nehme, Olivia Braillard, Francois Chappuis, Idris Guessous
Summary: This study found that 10-35% of COVID-19 cases in outpatient settings develop post-COVID condition. The duration and severity of symptoms contribute to the complexity and heterogeneity of post-COVID condition. Patients with chronic symptoms experience increased healthcare utilization, treatment needs, functional impairment, and poorer quality of life. Having multiple symptoms and difficulty concentrating at 7 months after infection are associated with a chronicity of symptoms.
SCIENTIFIC REPORTS
(2022)
Article
Neuroimaging
Merav Catalogna, Efrat Sasson, Amir Hadanny, Yoav Parag, Shani Zilberman-Itskovich, Shai Efrati
Summary: This study aimed to evaluate the effect of hyperbaric oxygen therapy (HBOT) on brain connectivity in post-COVID-19 patients. The results showed that HBOT improved disruptions in white matter tracts and altered the functional connectivity organization of neural pathways in the brain, promoting cognitive and emotional recovery in post-COVID-19 patients.
NEUROIMAGE-CLINICAL
(2022)
Article
Biochemistry & Molecular Biology
Siddharth Srivastava, Booil Jo, Bo Zhang, Thomas Frazier, Anne Snow Gallagher, Fleming Peck, April R. Levin, Sangeeta Mondal, Zetan Li, Rajna Filip-Dhima, Gregory Geisel, Kira A. Dies, Amelia Diplock, Charis Eng, Rabi Hanna, Mustafa Sahin, Antonio Hardan
Summary: This study investigated the safety and efficacy of everolimus in patients with PTEN hamartoma tumor syndrome (PHTS) and found that everolimus did not result in significant improvement in cognition and behavior, but showed potential efficacy in certain secondary measures.
HUMAN MOLECULAR GENETICS
(2022)
Article
Cell & Tissue Engineering
Li Ma, Qing Chang, Fei Pei, Mengmeng Liu, Wei Zhang, Young -Kwon Hong, Yang Chai, Jian-Fu Chen
Summary: The skull and brain functionally integrate through the meningeal lymphatic system, which may be impaired in certain craniosynostosis. Transplanting skull progenitor cells and treating with VEGF-C can restore the function of the meningeal lymphatic system, reduce intracranial pressure, and improve brain perfusion and neurocognitive functions.
Article
Medicine, General & Internal
Zhiguo Liu, Xirui Wang, Zhiyou Wu, Gangfeng Yin, Haibin Chu, Pengyue Zhao
Summary: This study compares the cognitive outcomes of normobaric hyperoxia (NBH) and hyperbaric oxygen therapy (HBOT) in mild traumatic brain injury (TBI) patients. It found that both NBH and HBOT can improve cognitive outcome and reduce brain injury, with HBOT showing better results.
Article
Nursing
Marian Wilson, Ross J. Bindler, Karen Stanek, Matthew E. Layton, Raymond M. Quock
Summary: This pilot study investigated the feasibility of hyperbaric oxygen therapy (HBOT) as a potential treatment adjunct for adults receiving methadone for opioid use disorder. The study found that participants receiving full-dose HBOT treatment showed greater improvements in pain intensity and drug craving compared to those receiving sham treatments. The results suggest that further research into non-pharmacologic options like HBOT is essential to improve clinical outcomes for individuals with opioid use disorder.
PAIN MANAGEMENT NURSING
(2022)
Article
Sport Sciences
Amir Hadanny, Yafit Hachmo, Daniella Rozali, Merav Catalogna, Eldad Yaakobi, Marina Sova, Hadar Gattegno, Ramzia Abu Hamed, Erez Lang, Nir Polak, Mony Friedman, Shachar Finci, Yonatan Zemel, Yair Bechor, Noga Gal, Shai Efrati
Summary: This study evaluated the effect of intermittent hyperbaric oxygen therapy (HBOT) on maximal physical performance and mitochondrial function in middle-aged master athletes. The results showed that HBOT significantly increased maximal oxygen consumption and oxygen consumption at the anaerobic threshold, as well as improved mitochondrial respiration and increased mitochondrial mass in healthy middle-aged master athletes.
SPORTS MEDICINE-OPEN
(2022)
Article
Health Care Sciences & Services
Yu-Wan Ho, Ping-Yen Chung, Sen-Kuang Hou, Ming-Long Chang, Yi-No Kang
Summary: This study provides an overview of various hyperbaric oxygen therapies for carbon monoxide poisoning. The results suggest that hyperbaric oxygen therapy does not have better outcomes compared to normobaric oxygen therapy for CO poisoning. Additionally, two-session hyperbaric oxygen therapy might lead to higher rates of general fatigue, memory impairment, and concentration impairment compared to one-session hyperbaric oxygen therapy. Clinicians should carefully consider treatment options before recommending hyperbaric oxygen therapy to patients with CO poisoning.
Article
Neurosciences
Allison M. Plummer, Yvette L. Matos, Henry C. Lin, Sephira G. Ryman, Aleksandr Birg, Davin K. Quinn, Alisha N. Parada, Andrei A. Vakhtin
Summary: Approximately one third of non-hospitalized COVID-19 patients experience chronic symptoms after recovering from the acute stage. Cognitive issues, such as brain fog and deficits in executive function, working memory, attention, and processing speed, are common in these patients. The mechanisms behind these chronic cognitive sequelae are not yet understood, but may involve damage to cerebral blood vessels and the intestinal wall, as well as the production of neurotoxic substances in the gut due to post-COVID-19 dysbiosis.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Multidisciplinary Sciences
Marina Leitman, Shmuel Fuchs, Vladimir Tyomkin, Amir Hadanny, Shani Zilberman-Itskovich, Shai Efrati
Summary: Post-COVID-19 patients with ongoing symptoms may have cardiac dysfunction, but hyperbaric oxygen therapy (HBOT) can promote left ventricular systolic function recovery.
SCIENTIFIC REPORTS
(2023)
Article
Endocrinology & Metabolism
Theresia Sarabhai, Lucia Mastrototaro, Sabine Kahl, Gidon J. Boenhof, Marc Jonuscheit, Pavel Bobrov, Hisayuki Katsuyama, Rainer Guthoff, Martin Wolkersdorfer, Christian Herder, Sven G. Meuth, Sven Dreyer, Michael Roden
Summary: This study aimed to examine the effects of hyperbaric oxygen therapy on whole-body glucose metabolism in individuals with type 2 diabetes. The results showed that hyperbaric oxygen therapy decreased fasting blood glucose, improved whole-body insulin sensitivity, and achieved this improvement through decreasing endoplasmic reticulum stress and increasing mitochondrial function.
Article
Biochemistry & Molecular Biology
Soo-yeon Park, Yong Dae Kim, Min Seo Kim, Ki-Tae Kim, Ji Yeon Kim
Summary: Cinnamon water extract (CWE) intake improved diarrhea symptoms and changed the composition of stools and gut microbiota. It increased colonic transit time and fecal isobutyric acid and spermidine contents, while decreasing fecal indole and agmatine contents. CWE also showed significant changes in strains of Bifidobacterium longum ATCC 55813 and increased alpha diversity in the gut microbiota.
Article
Medicine, Research & Experimental
Napatsorn Imerb, Chanisa Thonusin, Wasana Pratchayasakul, Busarin Arunsak, Wichwara Nawara, Ratchaneevan Aeimlapa, Narattaphol Charoenphandhu, Nipon Chattipakorn, Siriporn C. Chattipakorn
Summary: The aim of this study was to investigate the effects of hyperbaric oxygen therapy (HBOT) on metabolic disturbance, aging, and bone remodeling in D-galactose-induced aging rats with and without obesity. The results showed that a high-fat diet exacerbated bone dysregulation in D-galactose-treated rats. However, HBOT restored bone remodeling and structure/strength, and ameliorated bone dysregulation in the obesity group. These findings suggest that HBOT has the potential to decrease the risk of osteoporosis and bone fractures in aging individuals with or without obesity.