Valproate and Short-Chain Fatty Acids Activate Transcription of the Human Vitamin D Receptor Gene through a Proximal GC-Rich DNA Region Containing Two Putative Sp1 Binding Sites

Epistane, an anabolic steroid used for recreational purposes, causes cholestasis with elevated levels of cholic acid conjugates, by upregulating bile acid synthesis (CYP8B1) and cross-talking with nuclear receptors in human hepatocytes

(2020) Petar D. Petrov et al.   ARCHIVES OF TOXICOLOGY

The Vitamin D Receptor Regulates Glycerolipid and Phospholipid Metabolism in Human Hepatocytes

(2020) Teresa Martínez-Sena et al.   Biomolecules

Intestinal vitamin D receptor modulates lipid metabolism, adipose tissue inflammation and liver steatosis in obese mice

(2019) Daniel Jahn et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Valproic Acid and the Liver Injury in Patients with Epilepsy: An update

(2019) Hong-Li Guo et al.   CURRENT PHARMACEUTICAL DESIGN

Moving beyond sodium valproate: choosing the right anti-epileptic drug in children

(2019) Ganna Balagura et al.   EXPERT OPINION ON PHARMACOTHERAPY

Role of vitamin D receptor in the regulation of CYP3A gene expression

(2019) Xuan Qin et al.   Acta Pharmaceutica Sinica B

Fine tuning of vitamin D receptor (VDR) activity by post-transcriptional and post-translational modifications

(2017) Ondrej Zenata et al.   Oncotarget

New microRNA Biomarkers for Drug-Induced Steatosis and Their Potential to Predict the Contribution of Drugs to Non-alcoholic Fatty Liver Disease

(2017) Mireia López-Riera et al.   Frontiers in Pharmacology

Hepatocyte vitamin D receptor regulates lipid metabolism and mediates experimental diet-induced steatosis

(2016) Milica Bozic et al.   JOURNAL OF HEPATOLOGY

Human Upcyte Hepatocytes: Characterization of the Hepatic Phenotype and Evaluation for Acute and Long-Term Hepatotoxicity Routine Testing

(2016) Laia Tolosa et al.   TOXICOLOGICAL SCIENCES

Histone Deacetylase Inhibitors Modulate the Transcriptional Regulation of Guanylyl Cyclase/Natriuretic Peptide Receptor-A Gene

(2014) Prerna Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MMP28gene expression is regulated by Sp1 transcription factor acetylation

(2010) Tracey E. Swingler et al.   BIOCHEMICAL JOURNAL

Stimulation of 1,25-dihydroxyvitamin D3 receptor gene expression in cultured cells by serum and growth factors

(2010) Aruna V. Krishnan et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Valproic acid augments vitamin D receptor-mediated induction of CYP24 by vitamin D3: A possible cause of valproic acid-induced osteomalacia?

(2010) Radim Vrzal et al.   TOXICOLOGY LETTERS

Sp1 Phosphorylation and Its Regulation of Gene Transcription

(2009) N. Y. Tan et al.   MOLECULAR AND CELLULAR BIOLOGY

Sp1: Emerging roles—Beyond constitutive activation of TATA-less housekeeping genes

(2008) Inken Wierstra   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Attenuation of c-Jun and Sp1 expression and p300 recruitment to gene promoter confers the trichostatin A-induced inhibition of 12(S)-lipoxygenase expression in EGF-treated A431 cells

(2008) Ching-Jiunn Chen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY