Review
Biochemistry & Molecular Biology
Mengyu Hong, Ruilin Zhang, Yanan Liu, Zufang Wu, Peifang Weng
Summary: The interactions between tea polyphenols (TP) and intestinal microbiota play a significant role in ameliorating neurological diseases and enhancing host immunity. Based on the bidirectional relationship between the brain and the intestines, TP shows promise in improving host health through modulating intestinal bacteria.
JOURNAL OF FOOD BIOCHEMISTRY
(2022)
Review
Food Science & Technology
Qiao Xiang, Lu Cheng, Ruilin Zhang, Yanan Liu, Zufang Wu, Xin Zhang
Summary: This article summarizes the potential mechanism of how tea polyphenols influence COVID-19 through the intestinal microbiota. By reviewing and summarizing the latest research on tea polyphenols, the article suggests that tea polyphenols may inhibit the infection and life cycle of SARS-CoV-2, thus controlling and preventing COVID-19. These findings are of great significance for future specialized research in this field.
Article
Food Science & Technology
Van-Long Truong, Woo-Sik Jeong
Summary: Polyphenols, including phenolic acids, flavonoids, and procyanidins, are abundant in food and beverage derived from plants. Tea polyphenols have established antioxidant and anti-inflammatory properties, and their supplementation can prevent inflammatory conditions and improve the outcome of patients with inflammatory bowel diseases (IBD).
FOOD SCIENCE AND HUMAN WELLNESS
(2022)
Article
Food Science & Technology
Sarah Auguste, Bing Yan, Maolin Guo
Summary: Polyphenols found in tea can induce mitophagy in human fibroblast cells, and the induction of mitophagy may play an important role in the anti-aging mechanism of tea.
Article
Food Science & Technology
Ruonan Yan, Chi-Tang Ho, Xin Zhang
Summary: This article reviews the relationship between the host's circadian rhythm and microbiota and its influence on metabolic diseases, emphasizing the beneficial effects of the interaction between tea polyphenols and gut microbiota.
FOOD SCIENCE AND HUMAN WELLNESS
(2022)
Review
Food Science & Technology
Dan Song, Chung S. Yang, Xin Zhang, Ying Wang
Summary: The intestinal microbiota undergoes dietary-dependent fluctuations under the control of host circadian rhythms, playing a critical role in maintaining circadian rhythms and metabolic homeostasis. Interventions with prebiotics or probiotics may help alleviate circadian rhythm misalignment and related metabolic diseases. The interactions between tea polyphenols and intestinal microbiota can influence circadian rhythms, highlighting a potential area for further research.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2021)
Article
Food Science & Technology
Lei Xu, Rui Wang, Yanan Liu, Shengnan Zhan, Zufang Wu, Xin Zhang
Summary: Tea polyphenols have shown memory-enhancing activities and can effectively modulate the composition of the gut microbiota. The gut microbiota plays a critical role in the development of neurodegenerative diseases by regulating brain-gut axis function. Tea polyphenols have the advantage of multi-targeting and high safety profiles, making them potential neuroprotective substances with great potential in preventing and treating neurodegenerative diseases.
JOURNAL OF FUNCTIONAL FOODS
(2023)
Review
Nutrition & Dietetics
Jun Guo, Kai Li, Yajun Lin, Yinghua Liu
Summary: Aging is a key factor in cardiovascular diseases, which become more prevalent and severe with age. Understanding the mechanisms and interventions of cardiovascular aging is crucial for healthy aging. Tea polyphenols (TPs) are compounds found in tea leaves and have various effects on cardiovascular health. This article provides a detailed review of tea classification, composition, and its effects on cardiovascular diseases, including hypertension control, cholesterol reduction, antioxidant and anti-inflammatory abilities, as well as improving endothelial function and thrombosis prevention.
FRONTIERS IN NUTRITION
(2023)
Review
Food Science & Technology
Yuting Zhang, Lu Cheng, Yanan Liu, Zufang Wu, Peifang Weng
Summary: Negative emotions and sleep disorders are common health concerns in modern society. The relationship between gut microbiota and tea polyphenols (TP) in regulating mood and sleep is explored in this review. The gut microbiota can promote the metabolism and absorption of TP, while TP can modify the gut microbiota composition and inhibit harmful bacteria. Combining gut microbiota and TP in treatment options may be more effective than traditional pharmacological treatments, as gut microbiota can produce bioactive metabolites from dietary polyphenols that can regulate mood and sleep simultaneously to improve immunity.
FOOD REVIEWS INTERNATIONAL
(2023)
Review
Gastroenterology & Hepatology
Yanjiao Du, Yue Gao, Bo Zeng, Xiaolan Fan, Deying Yang, Mingyao Yang
Summary: Identifying ways to deal with the challenges of aging is crucial, with external factors like diet, exercise, and drug therapy, along with the intestinal microbiota, playing key roles in healthy aging. By regulating the homeostasis of intestinal flora and promoting a healthy intestinal environment, interventions based on intestinal microorganisms show great potential in combating aging and age-related diseases.
Review
Biochemistry & Molecular Biology
Yuting Zhang, Lu Cheng, Xin Zhang
Summary: Tea polyphenols (TP) are important functional components in tea, regulating human intestinal flora and being bio-transformed by intestinal microbiota into beneficial metabolites that protect nerves and promote neurocognition. Research highlights the significance of TP in protecting cerebral nerves through its effects on intestinal microflora and microbial degradation. Understanding the interaction between TP and intestinal microbiota, its implications for cerebral nerve protection, and the underlying mechanism can expand therapeutic applications of TP.
JOURNAL OF FOOD BIOCHEMISTRY
(2021)
Article
Agriculture, Multidisciplinary
Fang Zhou, Yi-Long Li, Xin Zhang, Kun-Bo Wang, Jian-An Huang, Zhong-Hua Liu, Ming-Zhi Zhu
Summary: The study found that FBTP supplementation effectively reduced obesity in HFD-fed rats by improving intestinal oxidative stress and barrier function, as well as attenuating gut microbiota dysbiosis induced by HFD. Specific core microbes, including Akkermansia muciniphila, Alloprevotella, Bacteroides, and Faecalibaculum, were improved by FBTPs. The antiobesity effect of FBTPs was shown to be dependent on gut microbiota, as demonstrated by a fecal microbiota transplantation experiment.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Review
Biochemistry & Molecular Biology
Xinzhou Wang, Yanan Liu, Zufang Wu, Peng Zhang, Xin Zhang
Summary: The intestinal flora plays a crucial role in maintaining human health, and tea polyphenols have the ability to regulate intestinal flora and potentially prevent and treat chronic diseases.
Review
Microbiology
Mengyu Hong, Lu Cheng, Yanan Liu, Zufang Wu, Peng Zhang, Xin Zhang
Summary: The hydroxyl groups and characteristic structural groups in tea polyphenols provide them with antioxidant activity, leading to anti-inflammatory effects and protection of intestinal flora and brain neurons. Microbial metabolites associated with the host have been identified as major regulators of the central nervous system. Studies on metabolites such as serotonin and short-chain fatty acids have identified multiple signaling pathways relevant to host health. However, the complexity and limitations of translating complex human diseases into animal models remain challenges. This article discusses several intestinal metabolites with research value, highlighting the interaction between tea polyphenols and chronic brain diseases mediated by the microbiota.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Agriculture, Multidisciplinary
Yuting Zhang, Lu Cheng, Yanan Liu, Ruilin Zhang, Zufang Wu, Kejun Cheng, Xin Zhang
Summary: Green tea polyphenols (GTP) have activities similar to prebiotics, which can improve circadian rhythm disturbances by regulating intestinal flora and related metabolites, as well as modifying circadian gene expression.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Integrative & Complementary Medicine
Ying Sun, Chi-Tang Ho, Yuting Zhang, Mengyu Hong, Xin Zhang
Summary: Considerable evidence suggests the important role of gut microbiota in human health by secreting metabolites that modulate essential biological processes. Cognitive impairment, commonly seen in psychiatric and neurological disorders, is closely related to gut microbiota. Intervention with plant polysaccharides to maintain intestinal micro-ecological balance has a significant impact on ameliorating cognitive impairment. This review focuses on the interaction between gut microbiota and plant polysaccharides, signaling pathogenesis of gut microbiota in cognitive impairment, and the effect of plant polysaccharides intervention on regulating gut microbiota as a promising strategy for ameliorating cognitive impairment.
JOURNAL OF TRADITIONAL AND COMPLEMENTARY MEDICINE
(2023)
Review
Agriculture, Multidisciplinary
Mei Yao, Xingfeng Shao, Yingying Wei, Xin Zhang, Hongfei Wang, Feng Xu
Summary: Dietary fiber plays a significant role in alleviating lead-induced neuroinflammation by regulating gut microbiota and the immune system, providing a potential dietary protective strategy.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Review
Agriculture, Multidisciplinary
Yuting Zhang, Lu Cheng, Yanan Liu, Shengnan Zhan, Zufang Wu, Songmei Luo, Xin Zhang
Summary: The relationship between diet, intestinal flora, and cognitive function is explored in this review. Dietary flavonoid supplementation is shown to have a protective effect against cognitive decline. The interaction between flavonoids and intestinal flora through the gut-brain axis is highlighted as a potential mechanism for improving cognitive impairment.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Review
Biochemistry & Molecular Biology
Qinghui He, Congcong Si, Zhenjiao Sun, Yuhui Chen, Xin Zhang
Summary: The imbalance of intestinal microbiota has a significant impact on human health, and the gut-brain axis plays a crucial role in improving depressive symptoms. Prebiotics such as plant polysaccharides and polyphenols can modulate the intestinal microbiota, offering potential for the prevention and treatment of depression.
Review
Food Science & Technology
Jiahao Yu, Xuwei Liu, Shanlin Xu, Ping Shao, Jiandong Li, Zhirong Chen, Xuanpeng Wang, Yang Lin, Catherine M. G. C. Renard
Summary: The development of polysaccharide-based films is driven by the problems with plastic materials and the film-forming properties of polysaccharides. In recent years, there has been a surge in research on using green solvents such as ionic liquids (ILs) and deep eutectic solvents (DESs) as alternatives to conventional solvents/plasticizers for preparing polysaccharide-based films. This review summarizes the properties and recovery of ILs and DESs, various green preparation strategies, and the characteristics of polysaccharide-based films with and without ILs and DESs. The advantages of these new solvents include high solubility for polysaccharides and better plasticizing ability compared to traditional plasticizers. They also possess antioxidant and antibacterial properties that are beneficial for applications in active food packaging films.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2023)
Review
Food Science & Technology
Zheyi Song, Renyi Song, Yanan Liu, Zufang Wu, Xin Zhang
Summary: The gut microbiota and the microbiota-gut-brain (MGB) axis have been a major focus of research in recent years. Ultra-processed foods (UPF) containing saturated fat, trans fat, added sugar, salt, and food additives have detrimental effects on gut and physical health. These components can disrupt gut microbiota functions and microbial metabolism, potentially affecting the neural network. Additionally, food additives, such as emulsifiers, artificial sweeteners, colorants, and preservatives, may be linked to metabolic diseases, inflammation, and alterations in gut microbiota composition and metabolites, thereby impacting cognition and behavior.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Food Science & Technology
Zheyi Song, Xin Zhang, Mengyu Hong, Zufang Wu, Songmei Luo, Kejun Cheng
Summary: Oolong tea polyphenols (OTP) have the potential to reduce cognitive dysfunction by modulating the gut microbiota. In a study on circadian rhythm disorder (CRD) mice, OTP treatment restored gut microbial disruption and improved cognitive impairments by up-regulating Akkermansia and Muribaculum and down-regulating Desulfovibrio.
JOURNAL OF FUNCTIONAL FOODS
(2023)
Review
Nutrition & Dietetics
Yidan Cai, Yanan Liu, Zufang Wu, Jing Wang, Xin Zhang
Summary: There is a close relationship between the intestinal microbiota and the circadian rhythm, regulated by the central-biological-clock system and the peripheral-biological-clock system. The intestinal flora also exhibits rhythmic oscillation. Poor diet and sedentary lifestyle can lead to immune and metabolic diseases. Numerous studies have shown that through diet, including fasting, and exercise, the human body can be influenced in its immune regulation, energy metabolism, and expression of biological-clock genes via the intestinal microbiota as the vector, resulting in reduced disease incidence rates. This article mainly discusses the effects of diet and exercise on the intestinal flora, immune, and metabolic systems from the perspective of the circadian rhythm, providing a more effective approach to prevent immune and metabolic diseases by modulating the intestinal microbiota.
Review
Nutrition & Dietetics
Li Zhang, Yuanshang Wang, Ying Sun, Xin Zhang
Summary: Metabolic disorders pose health risks and economic burdens. Gut microbiota plays a significant role in these disorders, influenced by diet and host activities. Unhealthy eating habits and sedentary lifestyles lead to harmful metabolite release, damaging the intestinal barrier and causing immune system and biochemical changes. Intermittent fasting and exercise interventions promote metabolic and inflammatory improvements, preventing metabolic disorders. This review discusses the link between gut microbiota and metabolic disorders, highlighting the effects of fasting and exercise on metabolic health.
Article
Food Science & Technology
Yuting Zhang, Junjie Pan, Yanan Liu, Xin Zhang, Kejun Cheng
Summary: More and more evidence supports the interaction between circadian rhythms and intestinal microbes, providing new insights into how dietary nutrition can improve host health. Our research showed that Ficus pandurata Hance var. angustifolia Cheng flavonoids (FCF) ameliorated colon damage and abnormal intestinal microflora in mice with circadian clock disorder and improved their exploration and memory behaviors. Mechanism studies revealed that FCF regulates metabolic pathways, tight junction protein expression in the colon, and levels of Aβ and inflammatory factors in the hippocampus.
Review
Food Science & Technology
Siyu Liu, Lu Cheng, Yanan Liu, Shengnan Zhan, Zufang Wu, Xin Zhang
Summary: Cognitive, mood, and sleep disorders are common and difficult to treat central nervous system disorders that significantly impact the lives of affected individuals. The gut-brain axis, which facilitates bidirectional information exchange between the gut microbiota and the nervous system, plays a vital role in the study of neurological disorders like neurodegenerative diseases. Dietary polyphenols have garnered attention due to their biological activity, diverse sources, structural variability, and low toxicity. Increasing the intake of dietary polyphenols is an emerging strategy for improving circadian rhythms and treating metabolic disorders by modulating the gut-brain axis.
Article
Food Science & Technology
Lei Xu, Rui Wang, Yanan Liu, Shengnan Zhan, Zufang Wu, Xin Zhang
Summary: Tea polyphenols have shown memory-enhancing activities and can effectively modulate the composition of the gut microbiota. The gut microbiota plays a critical role in the development of neurodegenerative diseases by regulating brain-gut axis function. Tea polyphenols have the advantage of multi-targeting and high safety profiles, making them potential neuroprotective substances with great potential in preventing and treating neurodegenerative diseases.
JOURNAL OF FUNCTIONAL FOODS
(2023)
Review
Food Science & Technology
Qiao Xiang, Yanan Liu, Zufang Wu, Rui Wang, Xin Zhang
Summary: Biological rhythm is a natural physiological phenomenon regulated by the biological rhythm system, including sleep cycle, body temperature fluctuation, endocrine level, and biological metabolism. Sleep disturbance, a main manifestation of circadian biological rhythm disorder, significantly affects work and quality of life. Research has shown that gut microbiota and circadian rhythms interact through the brain-gut pathway. Tea polyphenols can modulate the composition of intestinal microbiota, suggesting their potential use in improving sleep.
Article
Food Science & Technology
Xing Ge, Lu Cheng, Yanan Liu, Zufang Wu, Xin Zhang
Summary: The gut microbiota plays a critical role in regulating psychological behavior and improving cognition and emotion by regulating the integrity of the intestinal barrier.
