Substrate binding in the mitochondrial ADP/ATP carrier is a step-wise process guiding the structural changes in the transport cycle
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Substrate binding in the mitochondrial ADP/ATP carrier is a step-wise process guiding the structural changes in the transport cycle
Authors
Keywords
-
Journal
Nature Communications
Volume 13, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-06-23
DOI
10.1038/s41467-022-31366-5
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Diseases Caused by Mutations in Mitochondrial Carrier Genes SLC25: A Review
- (2020) Ferdinando Palmieri et al. Biomolecules
- The mitochondrial ADP/ATP carrier exists and functions as a monomer
- (2020) Edmund R.S. Kunji et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- The SLC25 Carrier Family: Important Transport Proteins in Mitochondrial Physiology and Pathology
- (2020) Edmund R. S. Kunji et al. PHYSIOLOGY
- A Single Cysteine Residue in the Translocation Pathway of the Mitosomal ADP/ATP Carrier from Cryptosporidium parvum Confers a Broad Nucleotide Specificity
- (2020) Martin S. King et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier
- (2019) Jonathan J. Ruprecht et al. CELL
- The yeast mitochondrial pyruvate carrier is a hetero‐dimer in its functional state
- (2019) Sotiria Tavoulari et al. EMBO JOURNAL
- Structural changes in the transport cycle of the mitochondrial ADP/ATP carrier
- (2019) Jonathan J Ruprecht et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- The SLC25 Mitochondrial Carrier Family: Structure and Mechanism
- (2019) Jonathan J. Ruprecht et al. TRENDS IN BIOCHEMICAL SCIENCES
- Screening of candidate substrates and coupling ions of transporters by thermostability shift assays
- (2018) Homa Majd et al. eLife
- Atomistic modeling of alternating access of a mitochondrial ADP/ATP membrane transporter with molecular simulations
- (2017) Koichi Tamura et al. PLoS One
- Calcium regulation of the human mitochondrial ATP-Mg/Pi carrier SLC25A24 uses a locking pin mechanism
- (2017) Steven P. D. Harborne et al. Scientific Reports
- Recurrent De Novo Dominant Mutations in SLC25A4 Cause Severe Early-Onset Mitochondrial Disease and Loss of Mitochondrial DNA Copy Number
- (2016) Kyle Thompson et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Formation of a cytoplasmic salt bridge network in the matrix state is a fundamental step in the transport mechanism of the mitochondrial ADP/ATP carrier
- (2016) Martin S. King et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- The transport mechanism of the mitochondrial ADP/ATP carrier
- (2016) Edmund R.S. Kunji et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Trends in Thermostability Provide Information on the Nature of Substrate, Inhibitor, and Lipid Interactions with Mitochondrial Carriers
- (2015) Paul G. Crichton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structures of yeast mitochondrial ADP/ATP carriers support a domain-based alternating-access transport mechanism
- (2014) J. J. Ruprecht et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Calcium-induced conformational changes of the regulatory domain of human mitochondrial aspartate/glutamate carriers
- (2014) Chancievan Thangaratnarajah et al. Nature Communications
- The substrate specificity of the human ADP/ATP carrier AAC1
- (2012) John Mifsud et al. MOLECULAR MEMBRANE BIOLOGY
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- Mitochondrial carriers function as monomers
- (2010) Edmund R.S. Kunji et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- The ADP and ATP transport in mitochondria and its carrier
- (2008) Martin Klingenberg BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Binding of ADP in the Mitochondrial ADP/ATP Carrier Is Driven by an Electrostatic Funnel
- (2008) François Dehez et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Electrostatic funneling of substrate in mitochondrial inner membrane carriers
- (2008) Y. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The mechanism of transport by mitochondrial carriers based on analysis of symmetry
- (2008) A. J. Robinson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microscale Fluorescent Thermal Stability Assay for Membrane Proteins
- (2008) Alexander I. Alexandrov et al. STRUCTURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started