Antigen glycosylation regulates efficacy of CAR T cells targeting CD19
Published 2022 View Full Article
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Title
Antigen glycosylation regulates efficacy of CAR T cells targeting CD19
Authors
Keywords
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Journal
Nature Communications
Volume 13, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-06-11
DOI
10.1038/s41467-022-31035-7
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- Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia
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- Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia
- (2018) Elena J. Orlando et al. NATURE MEDICINE
- Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1–2 trial
- (2018) Frederick L Locke et al. LANCET ONCOLOGY
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- (2018) Stephen J. Schuster et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2016) Avery D. Posey et al. IMMUNITY
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- (2016) Sabrina Jutz et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
- (2016) John G Doench et al. NATURE BIOTECHNOLOGY
- Secretome Analysis Identifies Novel Signal Peptide Peptidase-Like 3 (SPPL3) Substrates and Reveals a Role of SPPL3 in Multiple Golgi Glycosylation Pathways
- (2015) Peer-Hendrik Kuhn et al. MOLECULAR & CELLULAR PROTEOMICS
- Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia
- (2015) David L. Porter et al. Science Translational Medicine
- Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy
- (2015) E. Sotillo et al. Cancer Discovery
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- Easy quantitative assessment of genome editing by sequence trace decomposition
- (2014) Eva K. Brinkman et al. NUCLEIC ACIDS RESEARCH
- Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
- (2013) Ophir Shalem et al. SCIENCE
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