Bone marrow mesenchymal stem cell-derived extracellular vesicles containing miR-181d protect rats against renal fibrosis by inhibiting KLF6 and the NF-κB signaling pathway

MiR-181d-5p Targets KLF6 to Improve Ischemia/Reperfusion-Induced AKI Through Effects on Renal Function, Apoptosis, and Inflammation

(2020) Yue Zhang et al.   Frontiers in Physiology

Extracellular vesicles produced by bone marrow mesenchymal stem cells attenuate renal fibrosis, in part by inhibiting the RhoA/ROCK pathway, in a UUO rat model

(2020) Zhengzhou Shi et al.   Stem Cell Research & Therapy

Krϋppel-like factors (KLFs) in renal physiology and disease

(2019) Madhavi J. Rane et al.   EBioMedicine

Tumor Mesenchymal Stromal Cells Regulate Cell Migration of Atypical Teratoid Rhabdoid Tumor through Exosome-Mediated miR155/SMARCA4 Pathway

(2019) Yi-Ping Yang et al.   Cancers

microRNA-328 in exosomes derived from M2 macrophages exerts a promotive effect on the progression of pulmonary fibrosis via FAM13A in a rat model

(2019) Meng-Ying Yao et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Rat Mesenchymal Stromal Cell Sheets Suppress Renal Fibrosis via Microvascular Protection

(2019) Aya Imafuku et al.   Stem Cells Translational Medicine

Telbivudine attenuates UUO-induced renal fibrosis via TGF-β/Smad and NF-κB signaling

(2018) Jie Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mesenchymal stem cell-derived extracellular vesicles affect disease outcomes via transfer of microRNAs

(2018) Guanguan Qiu et al.   Stem Cell Research & Therapy

Cisplatin-resistant lung cancer cell–derived exosomes increase cisplatin resistance of recipient cells in exosomal miR-100–5p-dependent manner

(2017) Xiaobing Qin et al.   International Journal of Nanomedicine

Exosomes derived from miR-181-5p-modified adipose-derived mesenchymal stem cells prevent liver fibrosis via autophagy activation

(2017) Ying Qu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mesenchymal stem cell–derived extracellular vesicles attenuate kidney inflammation

(2017) Alfonso Eirin et al.   KIDNEY INTERNATIONAL

Effects of Bone Marrow Mesenchymal Stem Cells on Plasminogen Activator Inhibitor-1 and Renal Fibrosis in Rats with Diabetic Nephropathy

(2016) Hong Lang et al.   ARCHIVES OF MEDICAL RESEARCH

Mesenchymal Stem Cells Deliver Exogenous MicroRNA-let7c via Exosomes to Attenuate Renal Fibrosis

(2016) Bo Wang et al.   MOLECULAR THERAPY

Mesenchymal stem cell therapy ameliorates diabetic nephropathy via the paracrine effect of renal trophic factors including exosomes

(2016) Kanna Nagaishi et al.   Scientific Reports

Serum miR-181b Is Correlated with Hepatitis B Virus Replication and Disease Progression in Chronic Hepatitis B Patients

(2015) Fujun Yu et al.   DIGESTIVE DISEASES AND SCIENCES

JAK3/STAT6 Stimulates Bone Marrow-Derived Fibroblast Activation in Renal Fibrosis

(2015) J. Yan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Targeting the NLRP3 Inflammasome to Reduce Diet-Induced Metabolic Abnormalities in Mice

(2015) Fausto Chiazza et al.   MOLECULAR MEDICINE

Renal fibrosis in feline chronic kidney disease: Known mediators and mechanisms of injury

(2015) Jack Lawson et al.   VETERINARY JOURNAL

EZH2-mediated loss of miR-622 determines CXCR4 activation in hepatocellular carcinoma

(2015) Haiou Liu et al.   Nature Communications

Combination of Active Components of Xiexin Decoction Ameliorates Renal Fibrosis Through the Inhibition of NF-κB and TGF-β1/Smad Pathways in db/db Diabetic Mice

(2015) Jia-Sheng Wu et al.   PLoS One

Krüppel-like Factor 6 Is a Co-activator of NF-κB That Mediates p65-dependent Transcription of Selected Downstream Genes

(2014) Yu Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kruppel-like Transcription Factor 6 Regulates Inflammatory Macrophage Polarization

(2014) Dipali Date et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular Vesicles Released from Mesenchymal Stromal Cells Modulate miRNA in Renal Tubular Cells and Inhibit ATP Depletion Injury

(2014) Rafael S. Lindoso et al.   STEM CELLS AND DEVELOPMENT

miR-21–Containing Microvesicles from Injured Tubular Epithelial Cells Promote Tubular Phenotype Transition by Targeting PTEN Protein

(2013) Yang Zhou et al.   AMERICAN JOURNAL OF PATHOLOGY

Endothelial cells require miR-214 to secrete exosomes that suppress senescence and induce angiogenesis in human and mouse endothelial cells

(2013) B. W. M. van Balkom et al.   BLOOD

Intraparenchymal Injection of Bone Marrow Mesenchymal Stem Cells Reduces Kidney Fibrosis after Ischemia-Reperfusion in Cyclosporine-Immunosuppressed Rats

(2012) C. Alfarano et al.   CELL TRANSPLANTATION

Bone marrow stem cells-derived microvesicles protect against renal injury in the mouse remnant kidney model

(2012) JUAN HE et al.   NEPHROLOGY