4.6 Review

Recombination in Coronaviruses, with a Focus on SARS-CoV-2

Journal

VIRUSES-BASEL
Volume 14, Issue 6, Pages -

Publisher

MDPI
DOI: 10.3390/v14061239

Keywords

Coronaviridae; recombination; superinfection; coinfection; PANGOLIN; SARS-CoV-2; COVID-19

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Recombination is a common evolutionary tool for RNA viruses, including coronaviruses. This review examines the evidence for recombination in SARS-CoV-2 and addresses the naming of recombinants, their origin and fitness, and speculates on their potential impact on the future of the COVID-19 pandemics.
Recombination is a common evolutionary tool for RNA viruses, and coronaviruses are no exception. We review here the evidence for recombination in SARS-CoV-2 and reconcile nomenclature for recombinants, discuss their origin and fitness, and speculate how recombinants could make a difference in the future of the COVID-19 pandemics.

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