iRGD-mediated core-shell nanoparticles loading carmustine and O6-benzylguanine for glioma therapy

A Novel Strategy through Combining iRGD Peptide with Tumor-Microenvironment-Responsive and Multistage Nanoparticles for Deep Tumor Penetration

(2015) Xingli Cun et al.   ACS Applied Materials & Interfaces

3D culture broadly regulates tumor cell hypoxia response and angiogenesis via pro-inflammatory pathways

(2015) Peter DelNero et al.   BIOMATERIALS

Co-culture of 3D tumor spheroids with fibroblasts as a model for epithelial–mesenchymal transition in vitro

(2015) Sun-Ah Kim et al.   EXPERIMENTAL CELL RESEARCH

MGMT inactivation and clinical response in newly diagnosed GBM patients treated with Gliadel

(2015) Rachel Grossman et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Nanoparticles coated with the tumor-penetrating peptide iRGD reduce experimental breast cancer metastasis in the brain

(2015) Amanda M. Hamilton et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Survival outcomes and safety of carmustine wafers in the treatment of high-grade gliomas: a meta-analysis

(2015) Sajeel A. Chowdhary et al.   JOURNAL OF NEURO-ONCOLOGY

Radioactive 198Au-Doped Nanostructures with Different Shapes for In Vivo Analyses of Their Biodistribution, Tumor Uptake, and Intratumoral Distribution

(2014) Kvar C. L. Black et al.   ACS Nano

Tumor penetrability and anti-angiogenesis using iRGD-mediated delivery of doxorubicin-polymer conjugates

(2014) Ke Wang et al.   BIOMATERIALS

A Phase III study of radiation therapy (RT) and O6-benzylguanine + BCNU versus RT and BCNU alone and methylation status in newly diagnosed glioblastoma and gliosarcoma: Southwest Oncology Group (SWOG) study S0001

(2014) Deborah T. Blumenthal et al.   International Journal of Clinical Oncology

Marked effects of combined TPGS and PVA emulsifiers in the fabrication of etoposide-loaded PLGA-PEG nanoparticles: In vitro and in vivo evaluation

(2014) Roonak Saadati et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

The influence of the penetrating peptide iRGD on the effect of paclitaxel-loaded MT1-AF7p-conjugated nanoparticles on glioma cells

(2013) Guangzhi Gu et al.   BIOMATERIALS

Cationic core–shell nanoparticles with carmustine contained within O6-benzylguanine shell for glioma therapy

(2013) Lili Qian et al.   BIOMATERIALS

Peptides as Targeting Elements and Tissue Penetration Devices for Nanoparticles

(2012) Erkki Ruoslahti   ADVANCED MATERIALS

RGD-Based Strategies To Target Alpha(v) Beta(3) Integrin in Cancer Therapy and Diagnosis

(2012) Fabienne Danhier et al.   MOLECULAR PHARMACEUTICS

RGD-Modified PEG-PAMAM-DOX Conjugate: In Vitro and In Vivo Targeting to Both Tumor Neovascular Endothelial Cells and Tumor Cells

(2011) Saijie Zhu et al.   ADVANCED MATERIALS

Microscale mechanisms of agarose-induced disruption of collagen remodeling

(2011) Theresa A. Ulrich et al.   BIOMATERIALS

Treatment of recurrent glioblastoma with intra-arterial BCNU [1, 3-bis (2-chloroethyl)-1-nitrosourea]

(2010) Eberval Gadelha Figueiredo et al.   ARQUIVOS DE NEURO-PSIQUIATRIA

Pore size variable type I collagen gels and their interaction with glioma cells

(2010) Ya-li Yang et al.   BIOMATERIALS

The effectiveness of a magnetic nanoparticle-based delivery system for BCNU in the treatment of gliomas

(2010) Mu-Yi Hua et al.   BIOMATERIALS

Targeting O 6-methylguanine-DNA methyltransferase with specific inhibitors as a strategy in cancer therapy

(2010) Bernd Kaina et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

New Angiopep-Modified Doxorubicin (ANG1007) and Etoposide (ANG1009) Chemotherapeutics With Increased Brain Penetration

(2010) Christian Ché et al.   JOURNAL OF MEDICINAL CHEMISTRY

Coadministration of a Tumor-Penetrating Peptide Enhances the Efficacy of Cancer Drugs

(2010) K. N. Sugahara et al.   SCIENCE

Probing cellular mechanobiology in three-dimensional culture with collagen–agarose matrices

(2009) Theresa A. Ulrich et al.   BIOMATERIALS

Tissue-Penetrating Delivery of Compounds and Nanoparticles into Tumors

(2009) Kazuki N. Sugahara et al.   CANCER CELL

Multicellular spheroids in ovarian cancer metastases: Biology and pathology

(2009) Kristy Shield et al.   GYNECOLOGIC ONCOLOGY

Delivery of temozolomide to the tumor bed via biodegradable gel matrices in a novel model of intracranial glioma with resection

(2009) Umar Akbar et al.   JOURNAL OF NEURO-ONCOLOGY

C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration

(2009) T. Teesalu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced electrostatic interaction between chitosan-modified PLGA nanoparticle and tumor

(2008) Rui Yang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS