Development and optimization of pluronic® F127 and HPMC based thermosensitive gel for the skin delivery of metoprolol succinate

Title
Development and optimization of pluronic® F127 and HPMC based thermosensitive gel for the skin delivery of metoprolol succinate
Authors
Keywords
Metoprolol succinate, Central composite design, Penetration enhancers, Flux, Derringer's optimization tool, Hypotensive activity
Journal
Publisher
Elsevier BV
Online
2016-09-22
DOI
10.1016/j.jddst.2016.09.004

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